Regenerative Medicine & Tissue Bioengineering

BTB research lines can be divided in five blocks: amniotic membrane bank, cardiovascular bank, skin bank, ocular bank, and musculoskeletal bank. At the same time, these lines can be divided in three different sections: (1) new preservation techniques, (2) new processing technologies, and (3) therapeutic innovations. During the last years, part of the effort has been invested in the development of techniques to improve the methods and preservation times of the processed tissues, made available for clinical practice. Moreover, new processing methodologies such as decellularization have been addressed.

Main Lines of Research

• Tissue obtaining, clinical application, ethics and regulation. (Fariñas Barbera, Oscar; Savio Lopez, Andres).
• Preservation of living tissue. (Castells Sala, Cristina).
• Tissue decellularization. (Castells Sala, Cristina).
• Medical products of advanced therapies through the recellularization of decellularized tissues. (Castells Sala, Cristina).
• SoHo bioinks for 3D printing. (Fariñas Barbera, Oscar).
• Processing and products improvement. (Castells Sala, Cristina).
• Technical innovation for tissue processing. (Tabera Fernandez, Jaime).
• Extension of clinical indications of the grafts. (Fariñas Barbera, Oscar).
• Cellular therapy for eye diseases. (Castells Sala, Cristina).

Scientific Challenges

• Improvement and optimizations of the process related with the donor and tissue processing in clean rooms.
• Advances in the development of criteria, regulation and ethics for donors and tissues.
• Technical excellence related to the processing of cells, tissues and advanced therapy medical products (ATMP).
• Development of new approaches and medical products of advanced therapies for regenerative medicine.

Contact

Cristina Castells
ccastells@bst.cat