Search
01/11/2025
Defining molecular correlates of response using spatial transcriptomics in the SOGUG-AUREA trial
Ballesteros, PA, García-Carbonero, I, Gonzalez, EE, Marin, AP, Lorente, D, de Liaño, AG, Ortega, EM, Colomo, LJ, Puente, J, Gonzalez, I, Calvo, OF, Palacios, GA, Mendizabal, I, Navarro, EP, Domínguez, JID, Esteban-Villarrubia, J, Billalabeitia, EG, Oria, GAD. Defining molecular correlates of response using spatial transcriptomics in the SOGUG-AUREA trial. ANNALS OF ONCOLOGY. 2025; 36DOI:10.1016/j.annonc.2025.08.3696. PMID:. IF:65.400(Q1/1D).
01/11/2025
Characterization of locally advanced rectal cancer (LARC) patients (pt) in Spanish TTD-RETUD registry
España, MAG, Calle, SG, Flores, EG, Sosa, MM, Tocino, RV, Plazas, JG, Monteagudo, RF, Aguilera, MJS, Herrero, MDRM, Gargia, TG, Zafra, GM, Arévalo, MA, Orozco, EJ, Manrique, ACV, Alfonso, PG, Montes, AF, Ninerola, RQ, de Castro, EM, Verdaguer, H, García, RV. Characterization of locally advanced rectal cancer (LARC) patients (pt) in Spanish TTD-RETUD registry. ANNALS OF ONCOLOGY. 2025; 36DOI:10.1016/j.annonc.2025.08.1362. PMID:. IF:65.400(Q1/1D).
01/11/2025
Combined analysis of overall survival (OS) from the phase III CodeBreaK 300 and phase Ib CodeBreaK 101 studies of sotorasib 960 mg plus panitumumab (soto960+pani) therapy for chemorefractory KRAS G12C-mutated metastatic colorectal cancer (mCRC)
Kuboki, Y, Pietrantonio, F, Salvatore, L, Meriggi, FA, Modest, DP, Yaeger, R, Ruiz, E, Taieb, J, Karamouzis, MV, Esaki, T, Kim, TW, Cremolini, C, Strickler, JH, Masuishi, T, Paez, D, Chan, E, Chao, J, Tran, Q, Fakih, M, Hong, DS. Combined analysis of overall survival (OS) from the phase III CodeBreaK 300 and phase Ib CodeBreaK 101 studies of sotorasib 960 mg plus panitumumab (soto960+pani) therapy for chemorefractory KRAS G12C-mutated metastatic colorectal cancer (mCRC). ANNALS OF ONCOLOGY. 2025; 36DOI:10.1016/j.annonc.2025.08.1317. PMID:. IF:65.400(Q1/1D).
01/11/2025
Exploratory analysis of chromophobe renal cell carcinoma in the SUNNIFORECAST trial comparing Ipilimumab plus Nivolumab vs standard of care as first-line treatment
Ahrens, M, Haanen, JBAG, Albiges, L, Goupil, MG, Boleti, E, Gravis, G, Flechon, A, Grimm, MO, Bedke, J, Barthelemy, P, Gauna, DEC, Gonzalez, BM, Ivanyi, P, Rottey, S, Floercken, A, Rodriguez, CS, Rey, JPM, Burkholder, I, Hartmann, A, Bergmann, L. Exploratory analysis of chromophobe renal cell carcinoma in the SUNNIFORECAST trial comparing Ipilimumab plus Nivolumab vs standard of care as first-line treatment. ANNALS OF ONCOLOGY. 2025; 36DOI:10.1016/j.annonc.2025.08.3211. PMID:. IF:65.400(Q1/1D).
01/11/2025
Amivantamab-Chemotherapy in Non-Small Cell Lung Cancer with EGFR Exon 20 Insertions: Impact of Treatment Crossover and Other Endpoints from the Phase III PAPILLON Study
Sanborn, RE, Zhou, CC, Tang, KJ, Cho, BC, Cheng, S, Popat, S, Ono, A, Lu, S, Majem, M, Aguilar, A, Campelo, MDG, Hayashi, H, Lee, KY, Lee, SH, Delmonte, A, Alatorre-Alexander, J, Richardson, G, Santos, V, Dooms, C, Sabari, JK, Shu, CA, Girard, N, Mansfield, AS, Park, K, Xia, YC, Bhattacharya, A, Buyukkaramikli, N, Perualila, N, Diels, J, Acharya, S, Chandler, C, Proskorovsky, I, Dearden, L, Wortman-Vayn, H, Mahadevia, PJ, Knoblauch, RE, Agrawal, T, Baig, M, Felip, E. Amivantamab-Chemotherapy in Non-Small Cell Lung Cancer with EGFR Exon 20 Insertions: Impact of Treatment Crossover and Other Endpoints from the Phase III PAPILLON Study. Targeted Oncology. 2025; 20(6)DOI:10.1007/s11523-025-01182-0. PMID:41184595. IF:4.000(Q2/3D).
01/11/2025
Magnitude of clinical benefit demonstrated in trials supporting FDA and EMA Approval of drugs for hematological malignancies, 2020-2024
Cardozo, AR, Kesselheim, A, Tibau, A. Magnitude of clinical benefit demonstrated in trials supporting FDA and EMA Approval of drugs for hematological malignancies, 2020-2024. ANNALS OF ONCOLOGY. 2025; 36DOI:10.1016/j.annonc.2025.08.1886. PMID:. IF:65.400(Q1/1D).
01/11/2025
Real-world outcomes after immunotherapy discontinuation in advanced melanoma: Insights from the GEM1801 study
Muñoz-Couselo, E, Berciano-Guerrero, MA, Crespo, G, Castaño, AG, Manzano, JL, Miguel, PAD, Rosa, CA, Cerezuela-Fuentes, P, Puértolas, T, Sanz, LG, Medina, J, Cunquero-Tomás, A, Majem, M, Fernández, LA, Espinosa, E, Bellido, L, Soria, A, Bujosa, A, Algarra, SM, Marquez-Rodas, I. Real-world outcomes after immunotherapy discontinuation in advanced melanoma: Insights from the GEM1801 study. ANNALS OF ONCOLOGY. 2025; 36DOI:10.1016/j.annonc.2025.08.2263. PMID:. IF:65.400(Q1/1D).
01/11/2025
Relevance of the CPS score and tumor nephrectomy in the SUNNIFORECAST trial comparing ipilimumab/nivolumab versus standard of care in non-clear cell renal cell cancer
Bergmann, L, Albiges, L, Ahrens, M, Goupil, MG, Boleti, E, Gravis, G, Flechon, A, Grimm, MO, Bedke, J, Barthelemy, P, Gauna, DEC, Gonzalez, BM, Ivanyi, P, Floercken, A, Rodriguez, CS, Rey, JPM, Gruenwald, V, Burkholder, I, Hartmann, A, Haanen, JBAG. Relevance of the CPS score and tumor nephrectomy in the SUNNIFORECAST trial comparing ipilimumab/nivolumab versus standard of care in non-clear cell renal cell cancer. ANNALS OF ONCOLOGY. 2025; 36DOI:10.1016/j.annonc.2025.08.3216. PMID:. IF:65.400(Q1/1D).
01/11/2025
International multicenter retrospective study of spindle cell/ sclerosing rhabdomyosarcoma (S-RMS): A PUSH platform study
Chen, TWW, Giani, C, Ljevar, S, Reinhorn, D, Denu, R, Bhadri, VA, Jaeger, R, Ibrahim, T, D'Ambrosio, L, Bae, S, Han, I, Garcia, AS, Abreu, MH, Ribeiro, MFSA, Mariuk-Jarema, A, Yang, V, Sbaraglia, M, Antonescu, C, Baldi, GG, Stacchiotti, S. International multicenter retrospective study of spindle cell/ sclerosing rhabdomyosarcoma (S-RMS): A PUSH platform study. ANNALS OF ONCOLOGY. 2025; 36DOI:10.1016/j.annonc.2025.08.3306. PMID:. IF:65.400(Q1/1D).
01/11/2025
Molecular landscape of IDH1/2-mutant gliomas: A Spanish multicentric cohort
Cerna, JGY, Mirallas, O, Garces, VN, Puerto, DAG, Velilla, G, Pastor, PG, Puga, TG, Salgado, MAV, Martínez, A, Gonzalez, AH, Sorolla, MA, Di Muzio, A, González, M, Martinez-Garcia, MJ, Villacampa, G, Balana, C, Galceran, JC, Dienstmann, R, Sanchez, JMS, Vieito, M. Molecular landscape of IDH1/2-mutant gliomas: A Spanish multicentric cohort. ANNALS OF ONCOLOGY. 2025; 36DOI:10.1016/j.annonc.2025.08.1270. PMID:. IF:65.400(Q1/1D).
01/11/2025
Phase II of sunitinib plus nivolumab in advanced alveolar soft-part sarcoma results from the GEIS, ISG and UCL IMMUNOSARC II study
Muñiz, NH, Strauss, S, Redondo, A, Palmerini, E, Gaffaro, GJM, Chamberlain, FE, Martinez, V, Ibrahim, T, Trufero, JM, Morales, CMV, Billalabeitia, EG, Lleida, RT, Jiménez, CL, Mukherjee, U, Wan, S, Ramos, R, Garcia, AMG, Moura, DD, Martin-Broto, J. Phase II of sunitinib plus nivolumab in advanced alveolar soft-part sarcoma results from the GEIS, ISG and UCL IMMUNOSARC II study. ANNALS OF ONCOLOGY. 2025; 36DOI:10.1016/j.annonc.2025.08.3296. PMID:. IF:65.400(Q1/1D).
01/11/2025
Magnitude of clinical benefit of cancer medicines in curative setting and health technology assessment decisions in Europe
Hwang, T, Kesselheim, A, Tibau, A. Magnitude of clinical benefit of cancer medicines in curative setting and health technology assessment decisions in Europe. ANNALS OF ONCOLOGY. 2025; 36DOI:10.1016/j.annonc.2025.08.2893. PMID:. IF:65.400(Q1/1D).
01/11/2025
Assessing outcomes emerging after confirmatory trials of accelerated approval drugs, 1992-2021
Cardozo, AR, Tibau, A, Liu, I, Han, J, Cliff, E, Kesselheim, A. Assessing outcomes emerging after confirmatory trials of accelerated approval drugs, 1992-2021. ANNALS OF ONCOLOGY. 2025; 36DOI:10.1016/j.annonc.2025.08.2894. PMID:. IF:65.400(Q1/1D).
01/11/2025
Evaluation of a non-pharmacological skin care intervention for the prevention and treatment of skin toxicities induced by immunotherapy in oncology patients
Lopez, JS, Besora, CP, Malaret, M, Joaquín, AB, Recio, SM, Momblan, AM, Dalmau, GM, Majem, M. Evaluation of a non-pharmacological skin care intervention for the prevention and treatment of skin toxicities induced by immunotherapy in oncology patients. ANNALS OF ONCOLOGY. 2025; 36DOI:10.1016/j.annonc.2025.08.3451. PMID:. IF:65.400(Q1/1D).
01/11/2025
Navigating regulatory complexity in combined studies under clinical trial and in vitro diagnostic regulations: Lessons from the CHONQUER study on molecular prescreening for IDH1 mutation in chondrosarcoma
Blay, JY, Lleida, RT, Martin-Broto, J, Caetano, C, De Haan, JJ, Debruyne, C, Desar, I, Duffaud, F, Gelderblom, H, Gennigens, C, Italiano, A, Colomo, LJ, Lapeire, L, Mazzeo, F, Philip, J, Striefler, JK, Svobodova, M, Tala, I, Morales, CMV, Stacchiotti, S. Navigating regulatory complexity in combined studies under clinical trial and in vitro diagnostic regulations: Lessons from the CHONQUER study on molecular prescreening for IDH1 mutation in chondrosarcoma. ANNALS OF ONCOLOGY. 2025; 36DOI:10.1016/j.annonc.2025.08.3359. PMID:. IF:65.400(Q1/1D).
01/11/2025
CIRTUSARC: A multicenter, open-label phase II trial of cirtuvivint as second-line therapy in selected advanced soft-tissue sarcomas
Martin-Broto, J, Ospina, GM, Garcia, AS, Trufero, JM, Martinez-Garcia, J, Fidalgo, JAP, Morales, CMV, Jurado, JC, Ledesma, P, Grifman, M, Moura, DD, Muñiz, NH. CIRTUSARC: A multicenter, open-label phase II trial of cirtuvivint as second-line therapy in selected advanced soft-tissue sarcomas. ANNALS OF ONCOLOGY. 2025; 36DOI:10.1016/j.annonc.2025.08.3354. PMID:. IF:65.400(Q1/1D).
01/11/2025
Isocitrate dehydrogenase 1 (IDH1) mutation testing in the phase III study of ivosidenib vs placebo in IDH1-mutant conventional chondrosarcoma (CHONQUER)
Stacchiotti, S, Yonemori, K, Beato, CM, Campos, FAB, Conley, AP, Debruyne, C, Endo, M, Hiraga, H, Kichenadasse, G, Laptewicz, M, Lleida, RT, Morais, ANR, Yoshihiro, N, Pereira, C, Salawu, AT, Takenaka, S, Tanaka, K, Tinoco, G, Vianna, KM, Bovée, JVMG. Isocitrate dehydrogenase 1 (IDH1) mutation testing in the phase III study of ivosidenib vs placebo in IDH1-mutant conventional chondrosarcoma (CHONQUER). ANNALS OF ONCOLOGY. 2025; 36DOI:10.1016/j.annonc.2025.08.3355. PMID:. IF:65.400(Q1/1D).
01/11/2025
Personalizing antiemetic prophylaxis for patients at high emetic risk: Results from the MyRisk Trial
Molasiotis, A, Jordan, K, Karthaus, M, Dranitsaris, G, Roeland, EJ, Schwartzberg, LS, Bonizzoni, E, Vazquez, EB, Buchler, T, Cheng, Y, Christoph, DCC, Alfonso, PG, Lu, X, Majem, M, Mavroudis, D, Syrigos, K, Tomlins, E, Zhou, Z, Zimovjanova, M, Aapro, MS. Personalizing antiemetic prophylaxis for patients at high emetic risk: Results from the MyRisk Trial. ANNALS OF ONCOLOGY. 2025; 36DOI:10.1016/j.annonc.2025.08.3413. PMID:. IF:65.400(Q1/1D).
01/10/2025
Economic Burden of Disease Management and Recurrences After Complete Resection of Early-Stage ALK plus Non-Small Cell Lung Cancer (NSCLC) in Spain
Bernabé, R, De Castro, J, Collado, R, Escudero, V, Gutiérrez, F, Arranz, S, Gordo, R, Arroyo, I, Majem, M. Economic Burden of Disease Management and Recurrences After Complete Resection of Early-Stage ALK plus Non-Small Cell Lung Cancer (NSCLC) in Spain. Journal of Thoracic Oncology. 2025; 20(10)DOI:. PMID:. IF:20.800(Q1/1D).
01/10/2025
Phase 3 eVOLVE-Lung02 Trial of Volrustomig plus Chemotherapy (CT) vs Pembrolizumab plus CT in Metastatic NSCLC With PD-L1 TC <50%
Johnson, ML, Arriola, E, Kato, T, Girard, N, Gadgeel, S, Tarruella, MM, Newsom-Davis, T, Polaczek, M, Chen, X, Stefaniak, K, Lowery, C, Angra, N, Doherty, G, Ahn, MJ. Phase 3 eVOLVE-Lung02 Trial of Volrustomig plus Chemotherapy (CT) vs Pembrolizumab plus CT in Metastatic NSCLC With PD-L1 TC <50%. Journal of Thoracic Oncology. 2025; 20(10)DOI:. PMID:. IF:20.800(Q1/1D).
01/10/2025
Non-Pharmacological Dermatologic Care for the Prevention and Management of Immune-Related Skin Toxicities in Patients With Lung Cancer
Lopez, JS, Besora, CP, Verge, MM, Joaquin, AB, Recio, SM, Pastor, M, Fierro, JP, Martinez-Esparza, EH, Martinez-Momblan, MA, Majem, M. Non-Pharmacological Dermatologic Care for the Prevention and Management of Immune-Related Skin Toxicities in Patients With Lung Cancer. Journal of Thoracic Oncology. 2025; 20(10)DOI:. PMID:. IF:20.800(Q1/1D).
01/10/2025
NIVIPI-Brain: Phase 2 Study of Nivolumab plus Ipilimumab Combined With Chemotherapy in NSCLC With Synchronous Brain Metastases
Nadal, E, Cantero, A, Paz-Ares, L, Ortega, AL, Barba, A, Iranzo, P, Domine, M, Garcia, J, Blasco, A, Campelo, RG, Rodriguez-Abreu, D, Castro, RL, Vidal, OJ, Tena, I, Diz, P, Provencio, M, Simo, M, Vilariño, N, Navarro,, Bruna, J. NIVIPI-Brain: Phase 2 Study of Nivolumab plus Ipilimumab Combined With Chemotherapy in NSCLC With Synchronous Brain Metastases. Journal of Thoracic Oncology. 2025; 20(10)DOI:. PMID:. IF:20.800(Q1/1D).
01/10/2025
Histological Transformation as Resistance Mechanism in NSCLC: A Multicenter Study Exploring Clinico-Pathological and Molecular Features
Torresan, S, Torres, CSD, Caramella, C, Ambrosini, P, Gomez-Randulfe, I, Monaca, F, Ribera, A, Goudsmit, A, Michelini, A, Segui, V, Insa, A, Martorell, PM, Romero-Sola, G, Caro-Consuegra, R, Mirallas, O, Priano, I, Valdivia, A, Masfarré, L, Iranzo, P, Martinez-Marti, A, Cedres, S, Catot, S, Sequeira, T, Callejo, A, Bearz, A, Barba, A, Antoñanzas, M, Sais, E, Baena, J, Brandao, M, Mosteiro, M, Vilariño, N, Gambardella, V, Moran, T, Occhipinti, M, Califano, R, Pardo, N, Felip, E, Rocha, P. Histological Transformation as Resistance Mechanism in NSCLC: A Multicenter Study Exploring Clinico-Pathological and Molecular Features. Journal of Thoracic Oncology. 2025; 20(10)DOI:. PMID:. IF:20.800(Q1/1D).
01/10/2025
Benefits of Adjuvant Alectinib in ALK plus Early-Stage Non-Small Cell Lung Cancer, Recurrences Avoided and Savings for the Spanish Health System
De Castro, J, Bernabé, R, Escudero, V, Gutiérrez, F, Majem, M, Gordo, R, Arroyo, I, Arranz, S, Collado, R. Benefits of Adjuvant Alectinib in ALK plus Early-Stage Non-Small Cell Lung Cancer, Recurrences Avoided and Savings for the Spanish Health System. Journal of Thoracic Oncology. 2025; 20(10)DOI:. PMID:. IF:20.800(Q1/1D).
01/10/2025
ARIAN, Adjuvant Treatment With Sacituzumab and ZimberelimAb in Resected Patients: A Phase III Study-Trial in Progress
Provencio, M, Aguiar, D, Antoñanzas, M, Areses, MC, Azkárate, A, Barba, A, Bernabé, R, Blanco, R, Borregon, M, Campos, B, Coves, J, De Castro, J, Domènech, M, Domine, M, Campelo, RG, Gozálvez, CL, Huidobro, G, Insa, A, Juan-Vidal, O, Castro, RL, Martínez-Marti, A, Medina, S, Moreno, MA, Nadal, E, Olivares, A, Reguart, N, Sala, MA, Medina, K, Vilà, L, Massuti, B. ARIAN, Adjuvant Treatment With Sacituzumab and ZimberelimAb in Resected Patients: A Phase III Study-Trial in Progress. Journal of Thoracic Oncology. 2025; 20(10)DOI:. PMID:. IF:20.800(Q1/1D).
01/10/2025
IMscin002 Final Analysis: Patient Preference and Safety of Atezolizumab by Subcutaneous and Intravenous Administration
Cappuzzo, F, Zvirbule, Z, Korbenfeld, E, Kolb-Sielecki, J, Isla, D, Sanchez, AYC, Bustillos, A, Herraez-Baranda, L, Barata, T, Young, F, Majem, M. IMscin002 Final Analysis: Patient Preference and Safety of Atezolizumab by Subcutaneous and Intravenous Administration. Journal of Thoracic Oncology. 2025; 20(10)DOI:. PMID:. IF:20.800(Q1/1D).
01/10/2025
Early Treatment Discontinuation of Osimertinib in the Adjuvant Setting: Insights From the ADAURA Study
Grohé, C, Wu, YL, Tsuboi, M, Majem, M, John, T, Bolanos, A, Taylor, R, Sandelin, M, Herbst, RS. Early Treatment Discontinuation of Osimertinib in the Adjuvant Setting: Insights From the ADAURA Study. Journal of Thoracic Oncology. 2025; 20(10)DOI:. PMID:. IF:20.800(Q1/1D).
01/10/2025
A Multinational Phase 2 Randomized Pivotal Study of Sunvozertinib in Pretreated NSCLC With EGFR Exon 20 Insertion Mutations
Wang, M, Jänne, PA, Doucet, L, Fan, Y, Lv, D, Sun, M, Huang, D, Greillier, L, Planchard, D, Hong, Q, Mazieres, J, Felip, E, Li, X, Hu, Y, Fang, J, Bazhenova, L, Ghiringhelli, F, Dols, MAC, Rodriguez, LPA, Bearz, A, Ferreira, BP, Kim, YJ, Bosch-Barrera, J, Shim, BY, Luo, YH, Tiseo, M, Yang, TY, Carcereny, E, Memmott, R, Zalcman, G, Carpeño, JD, Di Noia, V, Parra, HS, Streich, G, Lee, D, Shum, E, Han, JY, Jaime, JC, Brungs, D, John, T, D'Arcangelo, M, Joaquín, AB, Liu, G, Antonuzzo, L, Fernandez-Hinojal, G, Le, X, Zheng, L, Yang, JCH. A Multinational Phase 2 Randomized Pivotal Study of Sunvozertinib in Pretreated NSCLC With EGFR Exon 20 Insertion Mutations. Journal of Thoracic Oncology. 2025; 20(10)DOI:. PMID:. IF:20.800(Q1/1D).
01/09/2025
Health-related quality of life in patients with KRASG12C-mutated chemorefractory metastatic colorectal cancer treated with sotorasib plus panitumumab or standard of care (CodeBreaK 300): results from a phase 3, randomised clinical trial
Modest, DP, Fakih, M, Salvatore, L, Esaki, T, Lopez-Bravo, DP, Taieb, J, Karamouzis, M, Ruiz-Garcia, E, Kim, TW, Kuboki, Y, Meriggi, F, Cunningham, D, Yeh, KH, Cremolini, C, Tran, Q, Chan, E, Chao, JS, Majer, IM, Pietrantonio, F. Health-related quality of life in patients with KRASG12C-mutated chemorefractory metastatic colorectal cancer treated with sotorasib plus panitumumab or standard of care (CodeBreaK 300): results from a phase 3, randomised clinical trial. LANCET ONCOLOGY. 2025; 26(9)DOI:10.1016/S1470-2045(25)00352-3. PMID:40812325. IF:35.900(Q1/1D).
01/09/2025
Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer
Audisio, A, Gallio, C, Velenik, V, Meillat, H, Ruiz-Garcia, E, Riesco, MC, Alecha, JS, Rasschaert, G, Carvalho, C, Randrian, V, Kirac, I, Hernando, J, Artac, M, O'Connor, JM, Waldhorn, I, Braam, PM, Shamseddine, A, Moretto, R, de la Pinta, C, De Felice, F, Dulskas, A, Lopez-Bravo, DP, Vanden Bulcke, A, Bock, F, Deleporte, A, van den Eynde, M, Geboes, KP, Loi, M, Messina, M, Houlze-Laroye, C, Puccini, A, Pastorino, A, Papamichael, D, Fiore, M, Sur, D, Eid, M, Antoun, C, Salati, M, Garajova, I, Jakubauskas, M, Tomasek, J, Pinto, CMS, Schwingel, J, Morano, F, Adams, RA, Dermine, A, Chau, A, Javed, MA, Ghidini, M, Fiorica, F, Montenegro, P, Petrillo, A, Spolverato, G, Margalef, NM, Diaz, M, Baratelli, C, Puleo, F, Karampeazis, A, Sert, F, Gilliaux, Q, De Stefano, A, Liberale, G, Moretti, L, Martinive, P, Thomas, VD, Staggs, V, Saad, ED, Van Laethem, JL, Sclafani, F. Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer. JAMA Oncology. 2025; 11(9)DOI:10.1001/jamaoncol.2025.2026. PMID:40638097. IF:20.100(Q1/1D).
10/02/2026
Subcutaneous administration of an endocrine-mimetic platform allows for prolonged tumor uptake of a tumor targeting protein
Alamo, P, López-Laguna, H, Favaro, MTP, Gallardo, A, Alba-Castellon, L, Villaverde, A, Mangues, R, Vázquez, E. Subcutaneous administration of an endocrine-mimetic platform allows for prolonged tumor uptake of a tumor targeting protein. INTERNATIONAL JOURNAL OF PHARMACEUTICS. 2026; 690DOI:10.1016/j.ijpharm.2026.126585. PMID:41521013. IF:5.200(Q1/2D).
01/03/2025
Surpassing protein specificity in biomimetics of bacterial amyloids
Sanchez, JM, Voltà-Durán, E, Parladé, E, Mangues, R, Villaverde, A, Vázquez, E, Unzueta, U. Surpassing protein specificity in biomimetics of bacterial amyloids. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 2025; 296DOI:10.1016/j.ijbiomac.2025.139635. PMID:39788253. IF:8.500(Q1/1D).
15/10/2023
High-precision targeting and destruction of cancer-associated PDGFR-ß(+) stromal fibroblasts through self-assembling, protein-only nanoparticles.
Voltà-Durán E, Alba-Castellón L, Serna N, Casanova I, López-Laguna H, Gallardo A, Sánchez-Chardi A, Villaverde A, Unzueta U, Vázquez E, Mangues R. High-precision targeting and destruction of cancer-associated PDGFR-ß(+) stromal fibroblasts through self-assembling, protein-only nanoparticles.. Acta Biomaterialia. 2023; 170DOI:10.1016/j.actbio.2023.09.001. PMID:37683965. IF:9.400(Q1/1D).
01/02/2026
Unravelling co-mutational patterns with prognostic implications in NPM1 mutated adult acute myeloid leukemia - a HARMONY study
Hernández-Sánchez, A, Ramiro, AV, Sträng, E, Turki, AT, Abáigar, M, Versluis, J, Thomas, I, Sobas, M, Elicegui, JM, Castellani, G, Benner, A, Azibeiro, R, Tettero, JM, Mecklenbrauck, R, Martínez-López, J, Pratcorona, M, Mills, KI, Sanz, G, Voso, MT, Sören, L, Röllig, C, Thiede, C, Metzeler, KH, Döhner, K, Heuser, M, Haferlach, T, Valk, PJM, Russell, N, Hernández-Rivas, JM, Huntly, B, Ossenkoppele, G, Döhner, H, Bullinger, L. Unravelling co-mutational patterns with prognostic implications in NPM1 mutated adult acute myeloid leukemia - a HARMONY study. LEUKEMIA. 2026; 40(2)DOI:10.1038/s41375-025-02851-9. PMID:41535568. IF:13.400(Q1/1D).
08/01/2026
Identification of two epitypes of IGHV unmutated chronic lymphocytic leukemia with distinct B-cell-related epigenetic imprinting and genetic alterations
Charalampopoulou, S, Ramos-Campoy, S, Duran-Ferrer, M, Puiggros, A, Kamaso, J, Nguyen-Khac, F, Rigolin, GM, Cuneo, A, Collado, R, García-Serra, R, Haferlach, C, Ortega, M, Abrisqueta, P, Bosch, F, Zenz, T, Blanco, ML, Salgado, R, García-Malo, MD, Gimeno, E, Lopez-Guillermo, A, Campo, E, Etter, L, Schoumans, J, Espinet, B, Martin-Subero, JI. Identification of two epitypes of IGHV unmutated chronic lymphocytic leukemia with distinct B-cell-related epigenetic imprinting and genetic alterations. Hemasphere. 2026; 10(1)DOI:10.1002/hem3.70211. PMID:41523081. IF:14.600(Q1/1D).
03/11/2025
Performance and clinical utility of germline genetic testing criteria for predisposition to myeloid neoplasms in adults
Torres-Esquius, S, Gabarros-Subira, M, Rivero, ME, López, GR, Mañó, LG, Lopez, F, Fernandez, C, Guijarro, F, Díaz-Beyá, M, Canela, MP, Acha, P, Jáuregui, SN, Tuset, E, Palomo, L, Valcarcel, D, Albareda, FB, Jerez, A, Montoro, MJ. Performance and clinical utility of germline genetic testing criteria for predisposition to myeloid neoplasms in adults. BLOOD. 2025; 146DOI:10.1182/blood-2025-4998. PMID:. IF:23.100(Q1/1D).
03/11/2025
Independent, international validation of the unsupervised harmony classification of Acute Myeloid Leukemia
Turki, A, Dall'Olio, D, Carota, L, Polizzi, S, Morote, M, Della Porta, M, Zhao, YM, Lanino, L, Sobas, M, Zhao, YQ, Sanchez, AH, Eric, S, Gimenez, LT, Abáigar, M, Elicegui, JM, Ramiro, AV, Dohner, K, Tettero, J, Esteve, J, Martinez-Lopez, J, Metzeler, K, Haferlach, T, Lehmann, S, Pratcorona, M, Thiede, C, Versluis, J, Mecklenbrauck, R, Heuser, M, Benner, A, Huntley, B, Rivas, JMH, Ossenkoppele, G, Döhner, H, Castellani, G, Bullinger, L. Independent, international validation of the unsupervised harmony classification of Acute Myeloid Leukemia. BLOOD. 2025; 146DOI:10.1182/blood-2025-451. PMID:. IF:23.100(Q1/1D).
01/05/2025
Comparative analysis of NGS and dPCR for measurable residual disease monitoring in intensively treated acute myeloid leukemia patients
Ramil, G, Artigas, A, Giné, A, Oñate, G, Castellet, H, Díaz-Beyá, M, Tormo, M, Cervera, M, Coll, R, Martínez-Serra, J, Vives, S, García-Guiñón, A, Mascaró, M, Gómez, L, García-Avila, S, Vall-Llovera, F, Gómez, R, Arnan, M, Salamero, O, Garrido, A, Esteve, J, Nomdedéu, J, Sierra, J, Pratcorona, M. Comparative analysis of NGS and dPCR for measurable residual disease monitoring in intensively treated acute myeloid leukemia patients. ANNALS OF HEMATOLOGY. 2025; 104(1)DOI:. PMID:. IF:2.400(Q2/5D).
01/10/2025
Complementary Role of IHC in ALK Fusion Detection: A Validation Study of NSCLC NGS-Based Screening in Seven Laboratories
Clavé, S, Montironi, C, Oliveras, G, Varela, M, Catasús, L, Sese, M, Hernández-Gallego, A, Teixido, C, Urbizu, A, González-Vidal, A, Pijuan, L, Sansano, I, Baixeras, N, Vásquez, C, Fuertes, B, Sánchez-Güerri, I, Lopez-Vilaro, L, Mate, JL, Bellosillo, B, Hernández-Losa, J, Muñoz-Mármol, AM. Complementary Role of IHC in ALK Fusion Detection: A Validation Study of NSCLC NGS-Based Screening in Seven Laboratories. Journal of Thoracic Oncology. 2025; 20(10)DOI:. PMID:. IF:20.800(Q1/1D).
01/09/2025
Prognostic significance of genetic biomarkers in glioblastoma IDH wild-type: a retrospective survival analysis
Herrera, IC, Fabregó, IE, Cols, LC, Lladó, MC, Vidal, AG, Martín, LF, Mariscal, IE, Arango, SMR, Metrallé, SCS, Alcañiz, AG. Prognostic significance of genetic biomarkers in glioblastoma IDH wild-type: a retrospective survival analysis. VIRCHOWS ARCHIV. 2025; 487DOI:. PMID:. IF:3.100(Q2/3D).