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01/11/2025
Self-disintegrating protein-leaking microparticles for topical protein delivery
Volta-Durán, E, Sánchez, JM, Favaro, MTP, Martinez-Cuentra, G, Contreras, E, di Somma, A, López-Laguna, H, Unzueta, U, Casanova, I, Mangues, R, Villaverde, A, Vázquez, E. Self-disintegrating protein-leaking microparticles for topical protein delivery. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 2025; 329DOI:10.1016/j.ijbiomac.2025.147730. PMID:40967544. IF:8.500(Q1/1D).
01/05/2025
Targeting the chemokine receptor CXCR4 for cancer therapies
Rueda, A, Serna, N, Mangues, R, Villaverde, A, Unzueta, U. Targeting the chemokine receptor CXCR4 for cancer therapies. Biomarker Research. 2025; 13(1)DOI:10.1186/s40364-025-00778-y. PMID:40307933. IF:11.500(Q1/1D).
11/03/2025
Trans-Mediated, Cis-Inhibited Paradoxal Activity of Clostridium perfringens Enterotoxin (c-CPE) in Modulating Epithelial Permeability
Sanchez, JM, Favaro, MTP, López-Laguna, H, Parladé, E, Di Somma, A, Casanova, I, Unzueta, U, Mangues, R, Vazquez, E, Voltà-Durán, E, Villaverde, A. Trans-Mediated, Cis-Inhibited Paradoxal Activity of Clostridium perfringens Enterotoxin (c-CPE) in Modulating Epithelial Permeability. MOLECULAR PHARMACEUTICS. 2025; 22(4)DOI:10.1021/acs.molpharmaceut.4c01205. PMID:40067325. IF:4.500(Q1/2D).
26/02/2025
Citrate-Assisted Regulation of Protein Stability and Secretability from Synthetic Amyloids
López-Laguna, H, Favaro, MTP, Chellou-Bakkali, S, Voltà-Durán, E, Parladé, E, Sánchez, J, Corchero, JL, Unzueta, U, Villaverde, A, Vázquez, E. Citrate-Assisted Regulation of Protein Stability and Secretability from Synthetic Amyloids. ACS Applied Materials & Interfaces. 2025; 17(10)DOI:10.1021/acsami.4c20784. PMID:40009529. IF:8.200(Q1/2D).
01/08/2024
Lyophilization of biomimetic amyloids preserves their regulatable, endocrine-like functions for nanoparticle release
Favaro, MTP, López-Laguna, H, Voltà-Durán, E, Alba-Castellon, L, Sánchez, JM, Casanova, I, Unzueta, U, Mangues, R, Villaverde, A, Vázquez, E. Lyophilization of biomimetic amyloids preserves their regulatable, endocrine-like functions for nanoparticle release. Applied Materials Today. 2024; 39DOI:10.1016/j.apmt.2024.102348. PMID:. IF:6.900(Q1/3D).
18/06/2024
Hybrid Micro-/Nanoprotein Platform Provides Endocrine-like and Extracellular Matrix-like Cell Delivery of Growth Factors
López-Laguna, H, Tsimbouri, PM, Jayawarna, V, Rigou, I, Serna, N, Voltà-Durán, E, Unzueta, U, Salmeron-Sanchez, M, Vázquez, E, Dalby, MJ, Villaverde, A. Hybrid Micro-/Nanoprotein Platform Provides Endocrine-like and Extracellular Matrix-like Cell Delivery of Growth Factors. ACS Applied Materials & Interfaces. 2024; 16(26)DOI:10.1021/acsami.4c01210. PMID:38888932. IF:8.200(Q1/2D).
19/03/2024
Structural Stabilization of Clinically Oriented Oligomeric Proteins During their Transit through Synthetic Secretory Amyloids
Sánchez, JM, López-Laguna, H, Parladé, E, Somma, AD, Livieri, AL, Alamo, P, Mangues, R, Unzueta, U, Villaverde, A, Vázquez, E. Structural Stabilization of Clinically Oriented Oligomeric Proteins During their Transit through Synthetic Secretory Amyloids. Advanced Science. 2024; 11(21)DOI:10.1002/advs.202309427. PMID:38501900. IF:14.100(Q1/1D).
01/11/2023
Efficient Delivery of Antimicrobial Peptides in an Innovative, Slow-Release Pharmacological Formulation
Serna, N, López-Laguna, H, Aceituno, P, Rojas-Peña, M, Parladé, E, Voltà-Durán, E, Martínez-Torró, C, Sánchez, JM, Di Somma, A, Carratalá, JV, Livieri, AL, Ferrer-Miralles, N, Vázquez, E, Unzueta, U, Roher, N, Villaverde, A. Efficient Delivery of Antimicrobial Peptides in an Innovative, Slow-Release Pharmacological Formulation. Pharmaceutics. 2023; 15(11)DOI:10.3390/pharmaceutics15112632. PMID:38004610. IF:4.900(Q1/2D).
13/03/2023
Biofabrication of Self-Assembling Covalent Protein Nanoparticles through Histidine-Templated Cysteine Coupling
López-Laguna H., Rueda A., Martínez-Torró C., Sánchez-Alba L., Carratalá J.V., Atienza-Garriga J., Parladé E., Sánchez J.M., Serna N., Voltà-Durán E., Ferrer-Miralles N., Reverter D., Mangues R., Villaverde A., Vázquez E., Unzueta U.. Biofabrication of Self-Assembling Covalent Protein Nanoparticles through Histidine-Templated Cysteine Coupling. ACS Sustainable Chemistry & Engineering. 2023; 11(10)DOI:10.1021/acssuschemeng.2c06635. PMID:. IF:7.100(Q1/2D).
01/01/2023
Endosomal escape for cell-targeted proteins. Going out after going in
Voltà-Durán E., Parladé E., Serna N., Villaverde A., Vazquez E., Unzueta U.. Endosomal escape for cell-targeted proteins. Going out after going in. BIOTECHNOLOGY ADVANCES. 2023; 63DOI:10.1016/j.biotechadv.2023.108103. PMID:36702197. IF:12.100(Q1/1D).
01/01/2023
Protein features instruct the secretion dynamics from metal-supported synthetic amyloids
Parladé E., Sánchez J.M., López-Laguna H., Unzueta U., Villaverde A., Vázquez E.. Protein features instruct the secretion dynamics from metal-supported synthetic amyloids. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 2023; 250DOI:10.1016/j.ijbiomac.2023.126164. PMID:37549767. IF:7.700(Q1/1D).
01/01/2023
Site-directed cysteine coupling of disulfide-containing non-antibody carrier proteins (THIOCAPs)
Rueda A., Mendoza J.I., Alba-Castellon L., Parladé E., Voltà-Durán E., Paez D., Aviño A., Eritja R., Vázquez E., Villaverde A., Mangues R., Unzueta U.. Site-directed cysteine coupling of disulfide-containing non-antibody carrier proteins (THIOCAPs). Science China-Materials. 2023; 66(10)DOI:10.1007/s40843-023-2571-6. PMID:. IF:6.800(Q1/3D).
01/12/2022
Protein scaffolds in human clinics
Cano-Garrido, O, Serna, N, Unzueta, U, Parlad, E, Mangues, R, Villaverde, A, Vazquez, E. Protein scaffolds in human clinics. BIOTECHNOLOGY ADVANCES. 2022; 61DOI:10.1016/j.biotechadv.2022.108032. PMID:36089254. IF:16.000(Q1/1D).
01/12/2022
The Diphtheria Toxin Translocation Domain Impairs Receptor Selectivity in Cancer Cell-Targeted Protein Nanoparticles
Volta-Duran, E, Sanchez, JM, Parlade, E, Serna, N, Vazquez, E, Unzueta, U, Villaverde, A. The Diphtheria Toxin Translocation Domain Impairs Receptor Selectivity in Cancer Cell-Targeted Protein Nanoparticles. Pharmaceutics. 2022; 14(12)DOI:10.3390/pharmaceutics14122644. PMID:36559138. IF:5.400(Q1/2D).
05/09/2022
Editorial: High added-value nanoparticles: Rethinking and recycling cell protein waste
Unzueta, U, Sanchez, JM, Garcia-Fruitos, E, Seras-Franzoso, J. Editorial: High added-value nanoparticles: Rethinking and recycling cell protein waste. Frontiers in Bioengineering and Biotechnology. 2022; 10DOI:10.3389/fbioe.2022.1018014. PMID:36131721. IF:5.700(Q1/3D).
01/07/2022
Involvement of the PI3K/AKT Intracellular Signaling Pathway in the AntiCancer Activity of Hydroxytyrosol, a Polyphenol from Olea europaea, in Hematological Cells and Implication of HSP60 Levels in Its Anti-Inflammatory Activity
Parra-Perez, AM, Perez-Jimenez, A, Gris-Cardenas, I, Bonel-Perez, GC, Carrasco-Diaz, LM, Mokhtari, K, Garcia-Salguero, L, Lupianez, JA, Rufino-Palomares, EE. Involvement of the PI3K/AKT Intracellular Signaling Pathway in the AntiCancer Activity of Hydroxytyrosol, a Polyphenol from Olea europaea, in Hematological Cells and Implication of HSP60 Levels in Its Anti-Inflammatory Activity. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022; 23(13)DOI:10.3390/ijms23137053. PMID:35806065. IF:5.600(Q1/3D).
01/11/2022
Predictors of thrombosis and bleeding in 1613 myelofibrosis patients from the Spanish Registry of Myelofibrosis
Hernandez-Boluda, JC, Pastor-Galan, I, Arellano-Rodrigo, E, Raya, JM, Perez-Encinas, M, Ayala, R, Ferrer-Marin, F, Velez, P, Mora, E, Fox, ML, Hernandez-Rivas, JM, Xicoy, B, Mata-Vazquez, MI, Garcia-Fortes, M, Perez-Lopez, R, Angona, A, Cuevas, B, Senin, A, Ramirez, MJ, Ramirez-Payer, A, Gomez-Casares, MT, Martinez-Valverde, C, Magro, E, Steegmann, JL, Duran, MA, Garcia-Hernandez, C, Gasior, M, de Villambrosia, SG, Alvarez-Larran, A, Pereira, A. Predictors of thrombosis and bleeding in 1613 myelofibrosis patients from the Spanish Registry of Myelofibrosis. BRITISH JOURNAL OF HAEMATOLOGY. 2022; 199(4)DOI:10.1111/bjh.18440. PMID:36089912. IF:6.500(Q1/3D).
01/10/2022
Low-risk polycythemia vera treated with phlebotomies: clinical characteristics, hematologic control and complications in 453 patients from the Spanish Registry of Polycythemia Vera
Triguero, A, Pedraza, A, Perez-Encinas, M, Mata-Vazquez, MI, Velez, P, Fox, L, Gomez-Calafat, M, Garcia-Delgado, R, Gasior, M, Ferrer-Marin, F, Garcia-Gutierrez, V, Angona, A, Gomez-Casares, MT, Cuevas, B, Martinez, C, Perez, R, Raya, JM, Guerrero, L, Murillo, I, Bellosillo, B, Hernandez-Boluda, JC, Sanz, C, Alvarez-Larran, A. Low-risk polycythemia vera treated with phlebotomies: clinical characteristics, hematologic control and complications in 453 patients from the Spanish Registry of Polycythemia Vera. ANNALS OF HEMATOLOGY. 2022; 101(10)DOI:10.1007/s00277-022-04963-z. PMID:36042023. IF:3.500(Q2/5D).
01/08/2022
Clonal heterogeneity and rates of specific chromosome gains are risk predictors in childhood high-hyperdiploid B-cell acute lymphoblastic leukemia
Ramos-Muntada, M, Trincado, JL, Blanco, J, Bueno, C, Rodriguez-Cortez, VC, Bataller, A, Lopez-Millan, B, Schwab, C, Ortega, M, Velasco, P, Blanco, ML, Nomdedeu, J, Ramirez-Orellana, M, Minguela, A, Fuster, JL, Cuatrecasas, E, Camos, M, Ballerini, P, Escherich, G, Boer, J, DenBoer, M, Hernandez-Rivas, JM, Calasanz, MJ, Cazzaniga, G, Harrison, CJ, Menendez, P, Molina, O. Clonal heterogeneity and rates of specific chromosome gains are risk predictors in childhood high-hyperdiploid B-cell acute lymphoblastic leukemia. Molecular Oncology. 2022; 16(16)DOI:10.1002/1878-0261.13276. PMID:35726693. IF:6.600(Q1/3D).
01/07/2022
Real-world analysis of main clinical outcomes in patients with polycythemia vera treated with ruxolitinib or best available therapy after developing resistance/intolerance to hydroxyurea
Alvarez-Larran, A, Garrote, M, Ferrer-Marin, F, Perez-Encinas, M, Mata-Vazquez, MI, Bellosillo, B, Arellano-Rodrigo, E, Gomez, M, Garcia, R, Garcia-Gutierrez, V, Gasior, M, Cuevas, B, Angona, A, Gomez-Casares, MT, Martinez, CM, Magro, E, Ayala, R, del Orbe-Barreto, R, Perez-Lopez, R, Fox, ML, Raya, JM, Guerrero, L, Garcia-Hernandez, C, Caballero, G, Murillo, I, Xicoy, B, Ramirez, MJ, Carreno-Tarragona, G, Hernandez-Boluda, JC, Pereira, A. Real-world analysis of main clinical outcomes in patients with polycythemia vera treated with ruxolitinib or best available therapy after developing resistance/intolerance to hydroxyurea. CANCER. 2022; 128(13)DOI:10.1002/cncr.34195. PMID:35417564. IF:6.200(Q1/3D).