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01/11/2025
Self-disintegrating protein-leaking microparticles for topical protein delivery
Volta-Durán, E, Sánchez, JM, Favaro, MTP, Martinez-Cuentra, G, Contreras, E, di Somma, A, López-Laguna, H, Unzueta, U, Casanova, I, Mangues, R, Villaverde, A, Vázquez, E. Self-disintegrating protein-leaking microparticles for topical protein delivery. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 2025; 329DOI:10.1016/j.ijbiomac.2025.147730. PMID:40967544. IF:8.500(Q1/1D).
01/05/2025
Targeting the chemokine receptor CXCR4 for cancer therapies
Rueda, A, Serna, N, Mangues, R, Villaverde, A, Unzueta, U. Targeting the chemokine receptor CXCR4 for cancer therapies. Biomarker Research. 2025; 13(1)DOI:10.1186/s40364-025-00778-y. PMID:40307933. IF:11.500(Q1/1D).
11/03/2025
Trans-Mediated, Cis-Inhibited Paradoxal Activity of Clostridium perfringens Enterotoxin (c-CPE) in Modulating Epithelial Permeability
Sanchez, JM, Favaro, MTP, López-Laguna, H, Parladé, E, Di Somma, A, Casanova, I, Unzueta, U, Mangues, R, Vazquez, E, Voltà-Durán, E, Villaverde, A. Trans-Mediated, Cis-Inhibited Paradoxal Activity of Clostridium perfringens Enterotoxin (c-CPE) in Modulating Epithelial Permeability. MOLECULAR PHARMACEUTICS. 2025; 22(4)DOI:10.1021/acs.molpharmaceut.4c01205. PMID:40067325. IF:4.500(Q1/2D).
26/02/2025
Citrate-Assisted Regulation of Protein Stability and Secretability from Synthetic Amyloids
López-Laguna, H, Favaro, MTP, Chellou-Bakkali, S, Voltà-Durán, E, Parladé, E, Sánchez, J, Corchero, JL, Unzueta, U, Villaverde, A, Vázquez, E. Citrate-Assisted Regulation of Protein Stability and Secretability from Synthetic Amyloids. ACS Applied Materials & Interfaces. 2025; 17(10)DOI:10.1021/acsami.4c20784. PMID:40009529. IF:8.200(Q1/2D).
01/08/2024
Lyophilization of biomimetic amyloids preserves their regulatable, endocrine-like functions for nanoparticle release
Favaro, MTP, López-Laguna, H, Voltà-Durán, E, Alba-Castellon, L, Sánchez, JM, Casanova, I, Unzueta, U, Mangues, R, Villaverde, A, Vázquez, E. Lyophilization of biomimetic amyloids preserves their regulatable, endocrine-like functions for nanoparticle release. Applied Materials Today. 2024; 39DOI:10.1016/j.apmt.2024.102348. PMID:. IF:6.900(Q1/3D).
18/06/2024
Hybrid Micro-/Nanoprotein Platform Provides Endocrine-like and Extracellular Matrix-like Cell Delivery of Growth Factors
López-Laguna, H, Tsimbouri, PM, Jayawarna, V, Rigou, I, Serna, N, Voltà-Durán, E, Unzueta, U, Salmeron-Sanchez, M, Vázquez, E, Dalby, MJ, Villaverde, A. Hybrid Micro-/Nanoprotein Platform Provides Endocrine-like and Extracellular Matrix-like Cell Delivery of Growth Factors. ACS Applied Materials & Interfaces. 2024; 16(26)DOI:10.1021/acsami.4c01210. PMID:38888932. IF:8.200(Q1/2D).
19/03/2024
Structural Stabilization of Clinically Oriented Oligomeric Proteins During their Transit through Synthetic Secretory Amyloids
Sánchez, JM, López-Laguna, H, Parladé, E, Somma, AD, Livieri, AL, Alamo, P, Mangues, R, Unzueta, U, Villaverde, A, Vázquez, E. Structural Stabilization of Clinically Oriented Oligomeric Proteins During their Transit through Synthetic Secretory Amyloids. Advanced Science. 2024; 11(21)DOI:10.1002/advs.202309427. PMID:38501900. IF:14.100(Q1/1D).
01/11/2023
Efficient Delivery of Antimicrobial Peptides in an Innovative, Slow-Release Pharmacological Formulation
Serna, N, López-Laguna, H, Aceituno, P, Rojas-Peña, M, Parladé, E, Voltà-Durán, E, Martínez-Torró, C, Sánchez, JM, Di Somma, A, Carratalá, JV, Livieri, AL, Ferrer-Miralles, N, Vázquez, E, Unzueta, U, Roher, N, Villaverde, A. Efficient Delivery of Antimicrobial Peptides in an Innovative, Slow-Release Pharmacological Formulation. Pharmaceutics. 2023; 15(11)DOI:10.3390/pharmaceutics15112632. PMID:38004610. IF:4.900(Q1/2D).
13/03/2023
Biofabrication of Self-Assembling Covalent Protein Nanoparticles through Histidine-Templated Cysteine Coupling
López-Laguna H., Rueda A., Martínez-Torró C., Sánchez-Alba L., Carratalá J.V., Atienza-Garriga J., Parladé E., Sánchez J.M., Serna N., Voltà-Durán E., Ferrer-Miralles N., Reverter D., Mangues R., Villaverde A., Vázquez E., Unzueta U.. Biofabrication of Self-Assembling Covalent Protein Nanoparticles through Histidine-Templated Cysteine Coupling. ACS Sustainable Chemistry & Engineering. 2023; 11(10)DOI:10.1021/acssuschemeng.2c06635. PMID:. IF:7.100(Q1/2D).
01/01/2023
Endosomal escape for cell-targeted proteins. Going out after going in
Voltà-Durán E., Parladé E., Serna N., Villaverde A., Vazquez E., Unzueta U.. Endosomal escape for cell-targeted proteins. Going out after going in. BIOTECHNOLOGY ADVANCES. 2023; 63DOI:10.1016/j.biotechadv.2023.108103. PMID:36702197. IF:12.100(Q1/1D).
01/01/2023
Protein features instruct the secretion dynamics from metal-supported synthetic amyloids
Parladé E., Sánchez J.M., López-Laguna H., Unzueta U., Villaverde A., Vázquez E.. Protein features instruct the secretion dynamics from metal-supported synthetic amyloids. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 2023; 250DOI:10.1016/j.ijbiomac.2023.126164. PMID:37549767. IF:7.700(Q1/1D).
01/01/2023
Site-directed cysteine coupling of disulfide-containing non-antibody carrier proteins (THIOCAPs)
Rueda A., Mendoza J.I., Alba-Castellon L., Parladé E., Voltà-Durán E., Paez D., Aviño A., Eritja R., Vázquez E., Villaverde A., Mangues R., Unzueta U.. Site-directed cysteine coupling of disulfide-containing non-antibody carrier proteins (THIOCAPs). Science China-Materials. 2023; 66(10)DOI:10.1007/s40843-023-2571-6. PMID:. IF:6.800(Q1/3D).
01/12/2022
Protein scaffolds in human clinics
Cano-Garrido, O, Serna, N, Unzueta, U, Parlad, E, Mangues, R, Villaverde, A, Vazquez, E. Protein scaffolds in human clinics. BIOTECHNOLOGY ADVANCES. 2022; 61DOI:10.1016/j.biotechadv.2022.108032. PMID:36089254. IF:16.000(Q1/1D).
01/12/2022
The Diphtheria Toxin Translocation Domain Impairs Receptor Selectivity in Cancer Cell-Targeted Protein Nanoparticles
Volta-Duran, E, Sanchez, JM, Parlade, E, Serna, N, Vazquez, E, Unzueta, U, Villaverde, A. The Diphtheria Toxin Translocation Domain Impairs Receptor Selectivity in Cancer Cell-Targeted Protein Nanoparticles. Pharmaceutics. 2022; 14(12)DOI:10.3390/pharmaceutics14122644. PMID:36559138. IF:5.400(Q1/2D).
05/09/2022
Editorial: High added-value nanoparticles: Rethinking and recycling cell protein waste
Unzueta, U, Sanchez, JM, Garcia-Fruitos, E, Seras-Franzoso, J. Editorial: High added-value nanoparticles: Rethinking and recycling cell protein waste. Frontiers in Bioengineering and Biotechnology. 2022; 10DOI:10.3389/fbioe.2022.1018014. PMID:36131721. IF:5.700(Q1/3D).
01/07/2022
Involvement of the PI3K/AKT Intracellular Signaling Pathway in the AntiCancer Activity of Hydroxytyrosol, a Polyphenol from Olea europaea, in Hematological Cells and Implication of HSP60 Levels in Its Anti-Inflammatory Activity
Parra-Perez, AM, Perez-Jimenez, A, Gris-Cardenas, I, Bonel-Perez, GC, Carrasco-Diaz, LM, Mokhtari, K, Garcia-Salguero, L, Lupianez, JA, Rufino-Palomares, EE. Involvement of the PI3K/AKT Intracellular Signaling Pathway in the AntiCancer Activity of Hydroxytyrosol, a Polyphenol from Olea europaea, in Hematological Cells and Implication of HSP60 Levels in Its Anti-Inflammatory Activity. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022; 23(13)DOI:10.3390/ijms23137053. PMID:35806065. IF:5.600(Q1/3D).
01/11/2022
Predictors of thrombosis and bleeding in 1613 myelofibrosis patients from the Spanish Registry of Myelofibrosis
Hernandez-Boluda, JC, Pastor-Galan, I, Arellano-Rodrigo, E, Raya, JM, Perez-Encinas, M, Ayala, R, Ferrer-Marin, F, Velez, P, Mora, E, Fox, ML, Hernandez-Rivas, JM, Xicoy, B, Mata-Vazquez, MI, Garcia-Fortes, M, Perez-Lopez, R, Angona, A, Cuevas, B, Senin, A, Ramirez, MJ, Ramirez-Payer, A, Gomez-Casares, MT, Martinez-Valverde, C, Magro, E, Steegmann, JL, Duran, MA, Garcia-Hernandez, C, Gasior, M, de Villambrosia, SG, Alvarez-Larran, A, Pereira, A. Predictors of thrombosis and bleeding in 1613 myelofibrosis patients from the Spanish Registry of Myelofibrosis. BRITISH JOURNAL OF HAEMATOLOGY. 2022; 199(4)DOI:10.1111/bjh.18440. PMID:36089912. IF:6.500(Q1/3D).
01/10/2022
Low-risk polycythemia vera treated with phlebotomies: clinical characteristics, hematologic control and complications in 453 patients from the Spanish Registry of Polycythemia Vera
Triguero, A, Pedraza, A, Perez-Encinas, M, Mata-Vazquez, MI, Velez, P, Fox, L, Gomez-Calafat, M, Garcia-Delgado, R, Gasior, M, Ferrer-Marin, F, Garcia-Gutierrez, V, Angona, A, Gomez-Casares, MT, Cuevas, B, Martinez, C, Perez, R, Raya, JM, Guerrero, L, Murillo, I, Bellosillo, B, Hernandez-Boluda, JC, Sanz, C, Alvarez-Larran, A. Low-risk polycythemia vera treated with phlebotomies: clinical characteristics, hematologic control and complications in 453 patients from the Spanish Registry of Polycythemia Vera. ANNALS OF HEMATOLOGY. 2022; 101(10)DOI:10.1007/s00277-022-04963-z. PMID:36042023. IF:3.500(Q2/5D).
01/08/2022
Clonal heterogeneity and rates of specific chromosome gains are risk predictors in childhood high-hyperdiploid B-cell acute lymphoblastic leukemia
Ramos-Muntada, M, Trincado, JL, Blanco, J, Bueno, C, Rodriguez-Cortez, VC, Bataller, A, Lopez-Millan, B, Schwab, C, Ortega, M, Velasco, P, Blanco, ML, Nomdedeu, J, Ramirez-Orellana, M, Minguela, A, Fuster, JL, Cuatrecasas, E, Camos, M, Ballerini, P, Escherich, G, Boer, J, DenBoer, M, Hernandez-Rivas, JM, Calasanz, MJ, Cazzaniga, G, Harrison, CJ, Menendez, P, Molina, O. Clonal heterogeneity and rates of specific chromosome gains are risk predictors in childhood high-hyperdiploid B-cell acute lymphoblastic leukemia. Molecular Oncology. 2022; 16(16)DOI:10.1002/1878-0261.13276. PMID:35726693. IF:6.600(Q1/3D).
01/07/2022
Real-world analysis of main clinical outcomes in patients with polycythemia vera treated with ruxolitinib or best available therapy after developing resistance/intolerance to hydroxyurea
Alvarez-Larran, A, Garrote, M, Ferrer-Marin, F, Perez-Encinas, M, Mata-Vazquez, MI, Bellosillo, B, Arellano-Rodrigo, E, Gomez, M, Garcia, R, Garcia-Gutierrez, V, Gasior, M, Cuevas, B, Angona, A, Gomez-Casares, MT, Martinez, CM, Magro, E, Ayala, R, del Orbe-Barreto, R, Perez-Lopez, R, Fox, ML, Raya, JM, Guerrero, L, Garcia-Hernandez, C, Caballero, G, Murillo, I, Xicoy, B, Ramirez, MJ, Carreno-Tarragona, G, Hernandez-Boluda, JC, Pereira, A. Real-world analysis of main clinical outcomes in patients with polycythemia vera treated with ruxolitinib or best available therapy after developing resistance/intolerance to hydroxyurea. CANCER. 2022; 128(13)DOI:10.1002/cncr.34195. PMID:35417564. IF:6.200(Q1/3D).
01/02/2022
The PML-RARA fusion is not detectable in historical blood samples of acute promyelocytic leukaemia patients
Dunn, WG, Gu, MXS, Fabre, MA, Cooper, J, Nomdedeu, JF, Koumas, L, Nicolaou, K, Chi, JX, Costeas, P, Vassiliou, GS. The PML-RARA fusion is not detectable in historical blood samples of acute promyelocytic leukaemia patients. ANNALS OF HEMATOLOGY. 2022; 101(2)DOI:10.1007/s00277-021-04472-5. PMID:33650061. IF:3.500(Q2/5D).
14/12/2021
Engraftment characterization of risk-stratified AML in NSGS mice
de la Guardia, RD, Velasco-Hernandez, T, Gutierrez-Aguera, F, Roca-Ho, H, Molina, O, Nombela-Arrieta, C, Bataller, A, Fuster, JL, Anguita, E, Vives, S, Zamora, L, Nomdedeu, J, Gomez-Casares, MT, Ramirez-Orellana, M, Lapillonne, H, Ramos-Mejia, V, Rodriguez-Manzaneque, JC, Bueno, C, Lopez-Millan, B, Menendez, P. Engraftment characterization of risk-stratified AML in NSGS mice. Blood Advances. 2021; 5(23)DOI:10.1182/bloodadvances.2020003958. PMID:34470043. IF:7.642(Q1/3D).
10/08/2021
The evolution of hematopoietic cells under cancer therapy
Pich, O, Cortes-Bullich, A, Muinos, F, Pratcorona, M, Gonzalez-Perez, A, Lopez-Bigas, N. The evolution of hematopoietic cells under cancer therapy. Nature Communications. 2021; 12(1)DOI:10.1038/s41467-021-24858-3. PMID:34376657. IF:17.694(Q1/1D).
01/08/2021
Myelodysplastic syndromes with 20q deletion: incidence, prognostic value and impact on response to azacitidine of ASXL1 chromosomal deletion and genetic mutations
Martin, I, Villamon, E, Abellan, R, Calasanz, MJ, Irigoyen, A, Sanz, G, Such, E, Mora, E, Gutierrez, M, Collado, R, Garcia-Serra, R, Vara, M, Blanco, ML, Oiartzabal, I, Alvarez, S, Bernal, T, Granada, I, Xicoy, B, Jerez, A, Calabuig, M, Diez, R, Gil, A, Diez-Campelo, M, Solano, C, Tormo, M. Myelodysplastic syndromes with 20q deletion: incidence, prognostic value and impact on response to azacitidine of ASXL1 chromosomal deletion and genetic mutations. BRITISH JOURNAL OF HAEMATOLOGY. 2021; 194(4)DOI:10.1111/bjh.17675. PMID:34296432. IF:8.615(Q1/2D).
01/07/2021
Sickle cell nephropathy. Clinical manifestations and new mechanisms involved in kidney injury
Payan-Pernia, S, Llobet, AR, Sevilla, AFR, Egido, J, Castan, JAB, Moreno, JA. Sickle cell nephropathy. Clinical manifestations and new mechanisms involved in kidney injury. NEFROLOGIA. 2021; 41(4)DOI:10.1016/j.nefro.2020.10.012. PMID:33714630. IF:3.084(Q2/5D).
01/10/2025
Diagnostic Value of Botryoid Nuclei as a Biomarker of Severe Hyperthermia and Systemic Inflammation in Heatstroke and Neuroleptic Malignant Syndrome: A Challenge of Climate Change
Verdú, G, Vallvé, M, San-José, P, Molina, A, Merino, A. Diagnostic Value of Botryoid Nuclei as a Biomarker of Severe Hyperthermia and Systemic Inflammation in Heatstroke and Neuroleptic Malignant Syndrome: A Challenge of Climate Change. International Journal of Laboratory Hematology. 2025; 47(5)DOI:10.1111/ijlh.14500. PMID:40391693. IF:2.300(Q2/5D).
01/09/2025
Telomere attrition becomes an instrument for clonal selection in aging hematopoiesis and leukemogenesis
Mcloughlin, MA, Kovilakam, SC, Dunn, WG, Gu, MX, Tobin, J, Pershad, Y, Williams, N, Leongamornlert, D, Dawson, K, Bond, L, Marando, L, Wen, S, Wilson, R, Valenzano, G, Symeonidou, V, Rak, J, Damaskou, A, Gozdecka, M, Liu, XX, Barcena, C, Nomdedeu, J, Costeas, P, Dimitriou, ID, Fiorillo, E, Orrù, V, de Almeida, JG, Mckerrell, T, Cullen, M, Mohorianu, I, Foukaneli, T, Warren, AJ, Wong, C, Follows, G, Godfrey, AL, Gudgin, E, Cucca, F, Mckinney, E, Baxter, EJ, Gerstung, M, Mitchell, J, Wiseman, D, Bick, AG, Fabre, M, Quiros, PM, Nangalia, J, Kar, S, Vassiliou, GS. Telomere attrition becomes an instrument for clonal selection in aging hematopoiesis and leukemogenesis. NATURE GENETICS. 2025; 57(9)DOI:10.1038/s41588-025-02296-x. PMID:40877435. IF:29.000(Q1/1D).
01/05/2025
D816V KIT mutation induces mitochondrial morphologic and functional changes through BNIP3 downregulation in human myeloid cell lines ROSA and TF-1
Wieczorek, SC, Hernández-Alvarez, MI, Parreño, M, Muñoz, JP, Bussaglia, E, Carricondo, M, Ubeda, J, Dubreuil, P, Zorzano, A, Brenet, F, Nomdedeu, JF. D816V KIT mutation induces mitochondrial morphologic and functional changes through BNIP3 downregulation in human myeloid cell lines ROSA and TF-1. EXPERIMENTAL HEMATOLOGY. 2025; 145DOI:10.1016/j.exphem.2025.104748. PMID:39986568. IF:2.100(Q3/6D).
19/08/2024
Genomic characterization of AML with aberrations of chromosome 7: a multinational cohort of 519 patients
Halik, A, Tilgner, M, Silva, P, Estrada, N, Altwasser, R, Jahn, E, Heuser, M, Hou, HA, Pratcorona, M, Hills, RK, Metzeler, KH, Fenwarth, L, Dolnik, A, Terre, C, Kopp, K, Blau, O, Szyska, M, Christen, F, Krönke, J, Vasseur, L, Löwenberg, B, Esteve, J, Valk, PJM, Duchmann, M, Chou, WC, Linch, DC, Döhner, H, Gale, RE, Döhner, K, Bullinger, L, Yoshida, K, Damm, F. Genomic characterization of AML with aberrations of chromosome 7: a multinational cohort of 519 patients. Journal of Hematology & Oncology. 2024; 17(1)DOI:10.1186/s13045-024-01590-1. PMID:39160538. IF:40.400(Q1/1D).
04/07/2024
Rearrangements involving 11q23.3/KMT2A in adult AML: mutational landscape and prognostic implications - a HARMONY study
Hernández-Sánchez, A, González, T, Sobas, M, Sträng, E, Castellani, G, Abáigar, M, Valk, PJM, Ramiro, AV, Benner, A, Metzeler, KH, Azibeiro, R, Tettero, JM, Martínez-López, J, Pratcorona, M, Elicegui, JM, Mills, KI, Thiede, C, Sanz, G, Döhner, K, Heuser, M, Haferlach, T, Turki, AT, Reinhardt, D, Schulze-Rath, R, Barbus, M, Hernández-Rivas, JM, Huntly, B, Ossenkoppele, G, Döhner, H, Bullinger, L. Rearrangements involving 11q23.3/KMT2A in adult AML: mutational landscape and prognostic implications - a HARMONY study. LEUKEMIA. 2024; 38(9)DOI:10.1038/s41375-024-02333-4. PMID:38965370. IF:13.400(Q1/1D).
03/06/2024
Titers of IgG and IgA against SARS-CoV-2 proteins and their association with symptoms in mild COVID-19 infection
Abril, AG, Alejandre, J, Mariscal, A, Alserawan, L, Rabella, N, Roman, E, Lopez-Contreras, J, Navarro, F, Serrano, E, Nomdedeu, JM, Vidal, S. Titers of IgG and IgA against SARS-CoV-2 proteins and their association with symptoms in mild COVID-19 infection. Scientific Reports. 2024; 14(1)DOI:10.1038/s41598-024-59634-y. PMID:38830902. IF:3.900(Q1/2D).
01/06/2024
Be aware of the X: BCOR mutations in myeloid neoplasms
Ramil, G, Pratcorona, M, Nomdedéu, JF. Be aware of the X: BCOR mutations in myeloid neoplasms. HAEMATOLOGICA. 2024; 109(6)DOI:10.3324/haematol.2023.284748. PMID:38328862. IF:10.100(Q1/2D).
01/04/2024
Validation of the Artificial Intelligence Prognostic Scoring System for Myelodysplastic Syndromes in chronic myelomonocytic leukaemia: A novel approach for improved risk stratification
Orgueira, AM, Encinas, MMP, Varela, ND, Wang, YH, Mora, E, Diaz-Beya, M, Montoro, MJ, Marin, HP, Ortega, FR, Tormo, M, Jerez, A, Nomdedeu, J, Sanchez, CD, Arenillas, L, Carcel, P, Romero, MTC, Cirici, BX, Arango, ER, Barreto, RAD, Benlloch, L, Lin, CC, Tien, HF, Míguez, CP, Crucitti, D, Campelo, MD, Valcárcel, D. Validation of the Artificial Intelligence Prognostic Scoring System for Myelodysplastic Syndromes in chronic myelomonocytic leukaemia: A novel approach for improved risk stratification. BRITISH JOURNAL OF HAEMATOLOGY. 2024; 204(4)DOI:10.1111/bjh.19341. PMID:38411250. IF:3.800(Q1/3D).
01/10/2023
Machine Learning Improves Risk Stratification in Myelodysplastic Neoplasms: An Analysis of the Spanish Group of Myelodysplastic Syndromes
Orgueira, AM, Encinas, MMP, Varela, NAD, Mora, E, Díaz-Beyá, M, Montoro, MJ, Pomares, H, Ramos, F, Tormo, M, Jerez, A, Nomdedeu, JF, Sanchez, CD, Leonor, A, Cárcel, P, Romero, MTC, Xicoy, B, Rivero, E, Barreto, RAD, Diez-Campelo, M, Benlloch, LE, Crucitti, D, Valcárcel, D. Machine Learning Improves Risk Stratification in Myelodysplastic Neoplasms: An Analysis of the Spanish Group of Myelodysplastic Syndromes. Hemasphere. 2023; 7(10)DOI:10.1097/HS9.0000000000000961. PMID:37841754. IF:11.900(Q1/1D).
01/08/2023
Incidence and prognostic impact of U2AF1 mutations and other gene alterations in myelodysplastic neoplasms with isolated 20q deletion
Castillo M.I., Ribate V.E., Muñoz C.M., Santillana S.G., Taboada S.E., Casterá M.E., Abinzano C.M.J., Barranco I.A., Nieto C.R., Pampliega V.M., Blanco M.L., de Andrés Á.S., de Oteyza P.J., del Castillo B.T., Font G.I., Cayuela J.A., Díez-Campelo M., Sánchez A.R., Vercet S.C., Díaz T.M.. Incidence and prognostic impact of U2AF1 mutations and other gene alterations in myelodysplastic neoplasms with isolated 20q deletion. Cancer Medicine. 2023; 12(16)DOI:10.1002/cam4.6300. PMID:37403747. IF:2.900(Q2/5D).
01/01/2023
Machine Learning Improves Risk Stratification in Myelofibrosis: An Analysis of the Spanish Registry of Myelofibrosis
Mosquera-Orgueira, A, Perez-Encinas, M, Hernandez-Sanchez, A, Gonzalez-Martinez, T, Arellano-Rodrigo, E, Martinez-Elicegui, J, Villaverde-Ramiro, A, Raya, JM, Ayala, R, Ferrer-Marin, F, Fox, ML, Velez, P, Mora, E, Xicoy, B, Mata-Vazquez, MI, Garcia-Fortes, M, Angona, A, Cuevas, B, Senin, MA, Ramirez-Payer, A, Ramirez, MJ, Perez-Lopez, R, de Villambrosia, SG, Martinez-Valverde, C, Gomez-Casares, MT, Garcia-Hernandez, C, Gasior, M, Bellosillo, B, Steegmann, JL, Alvarez-Larran, A, Hernandez-Rivas, JM, Hernandez-Boluda, JC. Machine Learning Improves Risk Stratification in Myelofibrosis: An Analysis of the Spanish Registry of Myelofibrosis. Hemasphere. 2023; 7(1)DOI:10.1097/HS9.0000000000000818. PMID:36570691. IF:11.900(Q1/1D).
01/01/2023
Epigenome profiling reveals aberrant DNA methylation signature in GATA2 deficiency
Marin-Bejar O., Romero-Moya D., Rodriguez-Ubreva J., Distefano M., Lessi F., Aretini P., Liquori A., Castaño J., Kozyra E., Kotmayer L., Bueno C., Cervera J., Rodriguez-Gallego J.C., Nomdedeu J.F., Murillo-Sanjuán L., De Heredia C.D., Pérez-Martinez A., López-Cadenas F., Martínez-Laperche C., Dorado-Herrero N., Marco F.M., Prósper F., Menendez P., Valcárcel D., Ballestar E., Bödör C., Bigas A., Catalá A., Wlodarski M.W., Giorgetti A.. Epigenome profiling reveals aberrant DNA methylation signature in GATA2 deficiency. HAEMATOLOGICA. 2023; 108(9)DOI:10.3324/haematol.2022.282305. PMID:36815365. IF:10.100(Q1/2D).
11/08/2022
Clinical, histological and molecular profiling of different stages of alcohol-related liver disease
Ventura-Cots, M, Argemi, J, Jones, PD, Lackner, C, El Hag, M, Abraldes, JG, Alvarado, E, Clemente, A, Ravi, S, Alves, A, Alboraie, M, Altamirano, J, Barace, S, Bosques, F, Brown, R, Caballeria, J, Cabezas, J, Carvalhana, S, Cortez-Pinto, H, Costa, A, Degre, D, Fernandez-Carillo, C, Ganne-Carrie, N, Garcia-Tsao, G, Genesca, J, Koskinas, J, Lanthier, N, Louvet, A, Lozano, JJ, Lucey, MR, Masson, S, Mathurin, P, Mendez-Sanchez, N, Miquel, R, Moreno, C, Mounajjed, T, Odena, G, Kim, W, Sancho-Bru, P, Sands, RW, Szafranska, J, Verset, L, Schnabl, B, Sempoux, C, Shah, VJ, Shawcross, DL, Stauber, RE, Straub, BK, Verna, E, Tiniakos, D, Trepo, E, Vargas, V, Villanueva, C, Woosley, JT, Ziol, M, Mueller, S, Starkel, P, Bataller, R. Clinical, histological and molecular profiling of different stages of alcohol-related liver disease. GUT. 2022; 71(9)DOI:10.1136/gutjnl-2021-324295. PMID:34992134. IF:24.500(Q1/1D).
03/07/2022
Multimodality imaging evaluation of a primary cardiac epithelioid hemangioendothelioma
Marsico, S, Orellana-Fernandez, R, Tizon-Marcos, H, Mas-Stachurska, A, Solano, A, Zuccarino, F. Multimodality imaging evaluation of a primary cardiac epithelioid hemangioendothelioma. ACTA CARDIOLOGICA. 2022; 77(6)DOI:10.1080/00015385.2021.1908704. PMID:33827376. IF:1.600(Q4/9D).
01/02/2022
Urinary Proteomic Signature in Acute Decompensated Heart Failure: Advances into Molecular Pathophysiology
Diaz-Riera, E, Garcia-Arguinzonis, M, Lopez, L, Garcia-Moll, X, Badimon, L, Padro, T. Urinary Proteomic Signature in Acute Decompensated Heart Failure: Advances into Molecular Pathophysiology. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022; 23(4)DOI:10.3390/ijms23042344. PMID:35216460. IF:5.600(Q1/3D).
01/01/2022
Neoadjuvant chemotherapy in high-risk soft tissue sarcomas: A Sarculator-based risk stratification analysis of the ISG-STS 1001 randomized trial
Pasquali, S, Palmerini, E, Quagliuolo, V, Martin-Broto, J, Lopez-Pousa, A, Grignani, G, Brunello, A, Blay, JY, Tendero, O, Diaz-Beveridge, R, Ferraresi, V, Lugowska, I, Infante, G, Braglia, L, Merlo, DF, Fontana, V, Marchesi, E, Donati, DM, Palassini, E, Bianchi, G, Marrari, A, Morosi, C, Stacchiotti, S, Bague, S, Coindre, JM, Dei Tos, AP, Picci, P, Bruzzi, P, Miceli, R, Casali, PG, Gronchi, A. Neoadjuvant chemotherapy in high-risk soft tissue sarcomas: A Sarculator-based risk stratification analysis of the ISG-STS 1001 randomized trial. CANCER. 2022; 128(1)DOI:10.1002/cncr.33895. PMID:34643947. IF:6.200(Q1/3D).
01/12/2021
A DNA damage repair gene-associated signature predicts responses of patients with advanced soft-tissue sarcoma to treatment with trabectedin
Moura, DS, Pena-Chilet, M, Varela, JAC, Alvarez-Alegret, R, Agra-Pujol, C, Izquierdo, F, Ramos, R, Ortega-Medina, L, Martin-Davila, F, Castilla-Ramirez, C, Hernandez-Leon, CN, Romagosa, C, Salgado, MAV, Lavernia, J, Bague, S, Mayodormo-Aranda, E, Vicioso, L, Barcelo, JEH, Rubio-Casadevall, J, de Juan, A, Fiano-Valverde, MC, Hindi, N, Lopez-Alvarez, M, Lacerenza, S, Dopazo, J, Gutierrez, A, Alvarez, R, Valverde, C, Martinez-Trufero, J, Martin-Broto, J. A DNA damage repair gene-associated signature predicts responses of patients with advanced soft-tissue sarcoma to treatment with trabectedin. Molecular Oncology. 2021; 15(12)DOI:10.1002/1878-0261.12996. PMID:33983674. IF:7.449(Q1/3D).
01/12/2021
Predictive Value of MRP-1 in Localized High-Risk Soft Tissue Sarcomas: A Translational Research Associated to ISG-STS 1001 Randomized Phase III Trial
Martin-Broto, J, Lopez-Alvarez, M, Moura, DS, Ramos, R, Collini, P, Romagosa, C, Bague, S, Renne, SL, Barisella, M, Velasco, V, Coindre, JM, Lopez-Lopez, D, Dopazo, J, Gambarotti, M, Braglia, L, Merlo, DF, Palmerini, E, Stacchiotti, S, Quagliuolo, VL, Lopez-Pousa, A, Grignani, G, Blay, JY, Brunello, A, Gutierrez, A, Valverde, C, Hindi, N, Dei Tos, AP, Picci, P, Casali, PG, Gronchi, A. Predictive Value of MRP-1 in Localized High-Risk Soft Tissue Sarcomas: A Translational Research Associated to ISG-STS 1001 Randomized Phase III Trial. MOLECULAR CANCER THERAPEUTICS. 2021; 20(12)DOI:10.1158/1535-7163.MCT-21-0315. PMID:34552008. IF:6.011(Q2/3D).
01/08/2021
Rational engineering of a human GFP-like protein scaffold for humanized targeted nanomedicines
Alamo, P, Cedano, J, Conchillo-Sole, O, Cano-Garrido, O, Alba-Castellon, L, Serna, N, Avino, A, Carrasco-Diaz, LM, Sanchez-Chardi, A, Martinez-Torro, C, Gallardo, A, Cano, M, Eritja, R, Villaverde, A, Mangues, R, Vazquez, E, Unzueta, U. Rational engineering of a human GFP-like protein scaffold for humanized targeted nanomedicines. Acta Biomaterialia. 2021; 130DOI:10.1016/j.actbio.2021.06.001. PMID:34116228. IF:10.633(Q1/2D).
01/07/2021
Atypical Endometrial Hyperplasia, Low-grade "Much ADO About Nothing"
D'Angelo, E, Espinosa, I, Cipriani, V, Szafranska, J, Barbareschi, M, Prat, J. Atypical Endometrial Hyperplasia, Low-grade "Much ADO About Nothing". AMERICAN JOURNAL OF SURGICAL PATHOLOGY. 2021; 45(7)DOI:10.1097/PAS.0000000000001705. PMID:34105519. IF:6.298(Q1/1D).
01/07/2021
A Novel NFIX-STAT6 Gene Fusion in Solitary Fibrous Tumor: A Case Report
Moura, DS, Diaz-Martin, J, Bague, S, Orellana-Fernandez, R, Sebio, A, Mondaza-Hernandez, JL, Salguero-Aranda, C, Rojo, F, Hindi, N, Fletcher, CDM, Martin-Broto, J. A Novel NFIX-STAT6 Gene Fusion in Solitary Fibrous Tumor: A Case Report. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021; 22(14)DOI:10.3390/ijms22147514. PMID:34299133. IF:6.208(Q1/3D).
01/07/2021
Predictive and prognostic value of total tumor load in sentinel lymph nodes in breast cancer patients after neoadjuvant treatment using one-step nucleic acid amplification: the NEOVATTL study
Vieites, B, Lopez-Garcia, MA, Martin-Salvago, MD, Ramirez-Tortosa, CL, Rezola, R, Sancho, M, Lopez-Vilaro, L, Villardell, F, Burgues, O, Fernandez-Rodriguez, B, Alfaro, L, Peg, V. Predictive and prognostic value of total tumor load in sentinel lymph nodes in breast cancer patients after neoadjuvant treatment using one-step nucleic acid amplification: the NEOVATTL study. Clinical & Translational Oncology. 2021; 23(7)DOI:10.1007/s12094-020-02530-4. PMID:33517542. IF:3.340(Q3/7D).
01/03/2025
CT-FIRE a Novel Technique in Quantitative Image Analysis of Collagen Fibers in Chronic Liver Disease Regression Animal Model
Szafranska, J, Batto, V, Alcaraz, J, Guinart-Cuadra, A, Brujats, A, Fajardo, J, Acin, V, Garcia, H, Casani, L, Villanueva, C, Ferré, M, del Olmo, TV, Tapias, EA. CT-FIRE a Novel Technique in Quantitative Image Analysis of Collagen Fibers in Chronic Liver Disease Regression Animal Model. LABORATORY INVESTIGATION. 2025; 105(3)DOI:10.1016/j.labinv.2024.103704. PMID:. IF:4.200(Q1/1D).
01/03/2025
Clinical Significance and Morphologic Characteristics of Non-Amyloid Heavy and Light Chain Deposition Disease in Gastrointestinal Mucosal Biopsy Specimens
Kelley, J, Hissong, E, Szafranska, J, Qin, LH, Lamps, L, Jessurun, J. Clinical Significance and Morphologic Characteristics of Non-Amyloid Heavy and Light Chain Deposition Disease in Gastrointestinal Mucosal Biopsy Specimens. LABORATORY INVESTIGATION. 2025; 105(3)DOI:10.1016/j.labinv.2024.102849. PMID:. IF:4.200(Q1/1D).
01/03/2025
Digital Spatial Profiling (DSP) Identifies Different Molecular Signatures Between Uterine Atypical Polyps and Adenosarcomas
D'Angelo, E, Kingsley, L, Espinosa, I, Cipriani, V, Marotta, A, Nasr, S, Zdravkovic, S, Howitt, B, Prat, J. Digital Spatial Profiling (DSP) Identifies Different Molecular Signatures Between Uterine Atypical Polyps and Adenosarcomas. LABORATORY INVESTIGATION. 2025; 105(3)DOI:10.1016/j.labinv.2024.103197. PMID:. IF:4.200(Q1/1D).
01/01/2025
A Targeted Nanotoxin Inhibits Colorectal Cancer Growth Through Local Tumor Pyroptosis and Eosinophil Infiltration and Degranulation
Carrasco-Díaz, LM, Gallardo, A, Voltà-Durán, E, Virgili, AC, Paez, D, Villaverde, A, Vazquez, E, Alamo, P, Unzueta, U, Casanova, I, Mangues, R, Alba-Castellon, L. A Targeted Nanotoxin Inhibits Colorectal Cancer Growth Through Local Tumor Pyroptosis and Eosinophil Infiltration and Degranulation. International Journal of Nanomedicine. 2025; 20DOI:10.2147/IJN.S499192. PMID:40034221. IF:6.500(Q1/1D).
01/12/2024
HMGA1 regulates trabectedin sensitivity in advanced soft-tissue sarcoma (STS): A Spanish Group for Research on Sarcomas (GEIS) study
Moura, DS, Mondaza-Hernandez, JL, Sanchez-Bustos, P, Peña-Chilet, M, Cordero-Varela, JA, Lopez-Alvarez, M, Carrillo-Garcia, J, Martin-Ruiz, M, Romero-Gonzalez, P, Renshaw-Calderon, M, Ramos, R, Marcilla, D, Alvarez-Alegret, R, Agra-Pujol, C, Izquierdo, F, Ortega-Medina, L, Martin-Davila, F, Hernandez-Leon, CN, Romagosa, C, Salgado, MAV, Lavernia, J, Bagué, S, Mayodormo-Aranda, E, Alvarez, R, Valverde, C, Martinez-Trufero, J, Castilla-Ramirez, C, Gutierrez, A, Dopazo, J, Hindi, N, Garcia-Foncillas, J, Martin-Broto, J. HMGA1 regulates trabectedin sensitivity in advanced soft-tissue sarcoma (STS): A Spanish Group for Research on Sarcomas (GEIS) study. CELLULAR AND MOLECULAR LIFE SCIENCES. 2024; 81(1)DOI:10.1007/s00018-024-05250-y. PMID:38758230. IF:6.200(Q1/2D).
01/10/2024
From the Rare to the Extraordinary Pancreatic Serous Cystadenocarcinoma With Hepatic and Bone Dissemination: A Letter to the Editor
Cardozo, A, Lleida, R, Szafranska, J, Piñol, D, Serdà, P, Martin-Cullell, B, Manrique, A, López-Bravo, D, Mateo, FJ. From the Rare to the Extraordinary Pancreatic Serous Cystadenocarcinoma With Hepatic and Bone Dissemination: A Letter to the Editor. PANCREAS. 2024; 53(9)DOI:10.1097/MPA.0000000000002362. PMID:39250559. IF:1.700(Q3/8D).
01/10/2024
RET overexpression in absence of fusions or mutations associates with sensitivity to RET TKIs in lung cancer
Sullivan, I, Aguado, C, Baroni, M, Teixeira, S, Bertran, J, Giménez, A, Aldeguer, E, Román, R, Reguart, N, López, L, Cavagna, R, Marín, E, García, B, Rodriguez, S, Rosell, R, Ferro, L, Chae, Y, Reis, R, Molina, MA. RET overexpression in absence of fusions or mutations associates with sensitivity to RET TKIs in lung cancer. EUROPEAN JOURNAL OF CANCER. 2024; 211DOI:10.1016/j.ejca.2024.114800. PMID:. IF:7.100(Q1/2D).
01/09/2024
ERCC1 and ERCC2 Polymorphisms Predict the Efficacy and Toxicity of Platinum-Based Chemotherapy in Small Cell Lung Cancer
Barba, A, López-Vilaró, L, Ferre, M, Majem, M, Martinez-Recio, S, Bell, O, Arranz, MJ, Salazar, J, Sullivan, I. ERCC1 and ERCC2 Polymorphisms Predict the Efficacy and Toxicity of Platinum-Based Chemotherapy in Small Cell Lung Cancer. Pharmaceutics. 2024; 16(9)DOI:10.3390/pharmaceutics16091121. PMID:39339159. IF:5.500(Q1/1D).
01/09/2024
Pancreatic adenocarcinoma associated with intraductal papillary mucinous neoplasm: a case series
Prat, A, Piñol, D, Espadaler, I, Campazas, I, Espinosa, I, Fusté, V, Szafranska, J, Fumagalli, C. Pancreatic adenocarcinoma associated with intraductal papillary mucinous neoplasm: a case series. VIRCHOWS ARCHIV. 2024; 485DOI:. PMID:. IF:3.100(Q2/3D).
01/09/2024
NKX2.2 expression in Ewing sarcoma: differences in sensitivity between pre-treatment biopsy and surgical specimen - a case series
Prat, A, Di Muro, MA, Acosta, SF, Vazquez, T, Rosell, SB, Orellana, R, Fumagalli, C. NKX2.2 expression in Ewing sarcoma: differences in sensitivity between pre-treatment biopsy and surgical specimen - a case series. VIRCHOWS ARCHIV. 2024; 485DOI:. PMID:. IF:3.100(Q2/3D).
01/09/2024
Prognostic impact of tumor location and gene expression profile in sporadic desmoid tumor
Carrillo-García, J, Hindi, N, Conceicao, M, Sala, MA, Ugalde, A, López-Pousa, A, Bagué, S, Sevilla, I, Vicioso, L, Ramos, R, Martínez-Trufero, J, Mateo, MCG, Cruz, J, Hernández-León, CN, Redondo, A, Mendiola, M, García, JM, Hernández, JE, Alvarez, R, Agra, C, de Juan-Ferré, A, Valverde, C, Cano, JM, de Sande, LM, Pérez-Fidalgo, JA, Lavernia, J, Marcilla, D, Gutiérrez, A, Moura, DS, Martín-Broto, J. Prognostic impact of tumor location and gene expression profile in sporadic desmoid tumor. EUROPEAN JOURNAL OF CANCER. 2024; 209DOI:10.1016/j.ejca.2024.114270. PMID:39142211. IF:7.100(Q1/2D).
01/08/2024
Spatial distribution of tumour immune in fi ltrate predicts outcomes of patients with high-risk soft tissue sarcomas after neoadjuvant chemotherapy
Pasquali, S, Vallacchi, V, Lalli, L, Collini, P, Barisella, M, Romagosa, C, Bague, S, Coindre, JM, Dei Tos, AP, Palmerini, E, Quagliuolo, V, Martin-Broto, J, Lopez-Pousa, A, Grignani, G, Blay, JY, Beveridge, RD, Casiraghi, E, Brich, S, Renne, SL, Bergamaschi, L, Vergani, B, Sbaraglia, M, Casali, PG, Rivoltini, L, Stacchiotti, S, Gronchi, A. Spatial distribution of tumour immune in fi ltrate predicts outcomes of patients with high-risk soft tissue sarcomas after neoadjuvant chemotherapy. EBioMedicine. 2024; 106DOI:10.1016/j.ebiom.2024.105220. PMID:39018755. IF:10.800(Q1/1D).
01/07/2024
Endometrial carcinoma: 10 years of TCGA (the cancer genome atlas): A critical reappraisal with comments on FIGO 2023 staging
Espinosa, I, D'Angelo, E, Prat, J. Endometrial carcinoma: 10 years of TCGA (the cancer genome atlas): A critical reappraisal with comments on FIGO 2023 staging. GYNECOLOGIC ONCOLOGY. 2024; 186DOI:10.1016/j.ygyno.2024.04.008. PMID:38615479. IF:4.100(Q1/1D).