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01/09/2025
Recommended Phase 2 Dose (RP2D) Determination of Bleximenib in Combination With Venetoclax plus Azacitidine (VEN plus AZA): Phase Ib Study in Newly Diagnosed (ND) and Relapsed/ Refractory (R/R) Acute Myeloid Leukemia (AML) With KMT2A or NPM1 Alterations
Wei, AH, Reyner, JE, Garciaz, S, Aldoss, I, Piérola, A, Allred, A, Dominguez, JMA, Barreyro, L, Bories, P, Daskalakis, N, Porta, MGD, Döhner, H, D'Souza, A, Dugan, J, Fathi, A, Fedele, P, Ferrante, L, Kobos, R, Gaj, S, Diaz, AG, Paniagua, SG, Guttke, C, Gyan, E, Hiebert, B, Jabbour, E, Trancucci, D, Bamidele, T, Jentzsch, M, Kantarjian, H, Konopleva, M, Krönke, J, Hütter-Krönke, ML, Loefgren, C, Lomas, O, Mancini, V, Mantzaris, I, Morillo, D, O'Nions, J, Packman, K, Papayannidis, C, Récher, C, Roellig, C, Salamero, O, Nagarajahastri, P, Sauer, T, Searle, E, Tovar, N, Vallet, N, Vaughan, L, Vega, G, Vyas, P, Platzbecker, U. Recommended Phase 2 Dose (RP2D) Determination of Bleximenib in Combination With Venetoclax plus Azacitidine (VEN plus AZA): Phase Ib Study in Newly Diagnosed (ND) and Relapsed/ Refractory (R/R) Acute Myeloid Leukemia (AML) With KMT2A or NPM1 Alterations. Clinical Lymphoma Myeloma & Leukemia. 2025; 25DOI:. PMID:. IF:2.700(Q2/4D).
01/09/2025
Phase 1b Study of Menin-KMT2A Inhibitor Bleximenib in Combination With Intensive Chemotherapy (IC) in Newly Diagnosed (ND) Acute Myeloid Leukemia (AML) with KMT2Ar or NPM1 Alterations
Jabbour, E, Recher, C, O'Nions, J, Aldoss, I, Pierola, A, Allred, A, Alonso-Dominguez, JM, Barreyro, L, Bories, P, Curtis, M, Daskalakis, N, Della Porta, MG, Döhner, H, D'Souza, A, Dugan, JP, Reyner, JE, Exum, M, Fathi, AT, Fedele, PL, Ferrante, L, Gaj, S, Garciaz, S, Garrido, A, Paniagua, SG, Guttke, C, Gyan, E, Hiebert, B, Jentzsch, M, Kantarjian, HM, Konopleva, M, Krönke, J, Kwon, MC, Loefgren, C, Lomas, O, Mancini, V, Mantzaris, I, Martinelli, G, Giles, DM, Murphy, J, Packman, K, Papayannidis, C, Philippar, U, Platzbecker, U, Rangaraju, S, Röllig, C, Salamero, O, Sanga, M, Sauer, T, Searle, E, Tovar, N, Tucker, T, Vallet, N, Vaughan, L, Vega, G, Vyas, P, Wei, A. Phase 1b Study of Menin-KMT2A Inhibitor Bleximenib in Combination With Intensive Chemotherapy (IC) in Newly Diagnosed (ND) Acute Myeloid Leukemia (AML) with KMT2Ar or NPM1 Alterations. Clinical Lymphoma Myeloma & Leukemia. 2025; 25DOI:. PMID:. IF:2.700(Q2/4D).
01/06/2025
Regression of pre-existing white matter hyperintensities after CD19 CAR Tcell induced ICANS: A case series
Borrell-Pichot, M, Lozano, A, Granell, E, Caballero, A, Briones-Mejide, J, Caballero-Avila, M, Vidal-Jordana, A, Querol, L, Mart n-Aguilar, L. Regression of pre-existing white matter hyperintensities after CD19 CAR Tcell induced ICANS: A case series. EUROPEAN JOURNAL OF NEUROLOGY. 2025; 32DOI:. PMID:. IF:3.900(Q1/3D).
01/05/2025
RNA-Seq analysis of the tumor microenvironment reveals prognostic subgroups in Acute Myeloid Leukemia with myelodysplasia-related gene mutations
Cortés-Bullich, A, Guijarro, F, Jiménez-Vicente, C, Bataller, A, Martínez-Roca, A, Triguero, A, Guerra, ML, Castaño-Diez, S, Oñate, G, Díaz-Beyá, M, Pich-Roselló, O, Esteve, J. RNA-Seq analysis of the tumor microenvironment reveals prognostic subgroups in Acute Myeloid Leukemia with myelodysplasia-related gene mutations. ANNALS OF HEMATOLOGY. 2025; 104(1)DOI:. PMID:. IF:2.400(Q2/5D).