Sant Pau - Institut de Recerca

Principales líneas investigación

Atención farmacéutica.
Nutrición artificial.
Oncohematología.
Ensayos clínicos independientes.

Retos

Evaluar el impacto en la eficacia y seguridad de los tratamientos farmacológicos en diferentes programas de atención farmacéutica: farmacocinética clínica, educación sanitaria de los pacientes ambulatorios, reconciliación e identificación de la medicación y prevención de los problemas relacionados con la medicación.
Evaluar el impacto de la nutrición artificial en la evolución clínica de los pacientes.
Estudio de la estabilidad de citostáticos en diferentes condiciones de uso.
Predecir la respuesta al tratamiento anti-tumoral en un número de procesos tumorales.
Desarrollar inhibidores de adhesión focal, por ejemplo, agentes antitumorales.
Cooperar activamente en los ensayos clínicos independientes realizados por nuestro Instituto.

Coordinación del grupo

FELIU RIBERA, ANNA FGS
afeliu@santpau.cat

Miembros

Amoros Reboredo, Patricia FGS
Berga Garrote, Nuria IR
Borrazas Olveira, Maria Belen FGS
Cardenete Ornaque, Juana FGS
De Dios Lopez, Anna FGS
De Pourcq, Jan Thomas FGS
Edo Peñarrocha, Josep FGS
Fernandez de Gamarra Martinez, Edurne FGS
Fuset Gonzalez, Marina IR
Gamez Lechuga, Maria FGS
Garin Escriva, Noe FGS
Gaso Gago, Ingrid FGS
Gavilan Rubio, Martina IR
Gonzalez Moraga, Marta IR
Gras Martin, Laura IR
Jorba Cortada, Celia IR
Juanes Borrego, Ana Maria FGS
Juanes Borrego, Maria Elena IR
Marcos Fendian, Angel FGS
Masip Torne, Montserrat FGS
Medina Catalan, David FGS
Moreno Martinez, Maria Estela FGS
Pages Puigdemont, Neus FGS
Pelegrin Cruz, Rebeca FGS
Plaza Diaz, Adrian FGS
Rey Vecino, Pau FGS
Riba Sole, Mireia FGS
Rodriguez Murphy, Esther FGS
Rodriguez-Arias Pal, Ainhoa IR
Rovira Medina, Teresa FGS
Ruiz Ramos, Jesus FGS
Vallez Valero, Lucia FGS
Vila Gallego, Clara FGS
Villamarin Vallejo, Laura FGS
Zafri Kasas, Nabila IR
Zarate Tamames, Borja FGS

Publicaciones 2023

(JIF 2023)

-Aguilar R, Gispert MA, de Gamarra EF, Martinez L, Garcia M, Pi N, Salgado E, Nogue S. An antidote network in Spain, a tool to improve antidote availability in hospitals. EUROPEAN JOURNAL OF HOSPITAL PHARMACY. 2023; 30(2):e03328. DOI:10.1136/ejhpharm-2022-003328. PMID:35501035. IF:1,600 (Q3/8D). Document type: Letter.

-Calleja MA, Albanell J, Aranda E, García J, Feliu A, Rivera F, Oyagüez I, Salinas L, Alvarez JS. Budget impact analysis of bevacizumab biosimilars for cancer treatment in adult patients in Spain. EUROPEAN JOURNAL OF HOSPITAL PHARMACY. 2023; 30(1):002955. DOI:10.1136/ejhpharm-2021-002955. PMID:34810173. IF:1,600 (Q3/8D). Document type: Article.

-De Pourcq JT, Riera P. Critical Commentary on the paper: Compatibility of prolonged infusion antibiotics during Y-site administration with parenteral nutrition. Nursing in Critical Care. 2023; 28(6). DOI:10.1111/nicc.12910. PMID:37232328. IF:3,000 (Q1/1D). Document type: Editorial Material.

-Domingo C, Fernandez M, Garin N, Milara J, Moran I, Muerza I, Pacheco A, Teruel C, Bentley R, Subiran R, Gil A. Determining What Represents Value in the Treatment of Refractory or Unexplained Chronic Cough from the Perspective of Key Stakeholders in Spain Using Multi-Criteria Decision Analysis. Applied Health Economics and Health Policy. 2023; 21(1). DOI:10.1007/s40258-022-00770-9. PMID:36319945. IF:3,100 (Q1/2D). Document type: Article.

-Duncan N, Moreno ME, Pires V, Domingos V, Bonnin A, Nezvalova K, Admiraal R, Bauters T, Langebrake C, Pharmacist E. Role and competencies of the EBMT clinical pharmacists and clinical pharmacologists: a pan-European survey. BONE MARROW TRANSPLANTATION. 2023; 58(7). DOI:10.1038/s41409-023-01983-9. PMID:37029183. IF:4,500 (Q1/2D). Document type: Letter.

-Garin N, Zarate B, Gras L, Mila R, Crespo A, Curto E, Hernandez M, Mestres C, Plaza V. Clinical Impact of Electronic Monitoring Devices of Inhalers in Adults with Asthma or COPD: A Systematic Review and Meta-Analysis. Pharmaceuticals. 2023; 16(3):414. DOI:10.3390/ph16030414. PMID:36986513. IF:4,300 (Q1/2D). Document type: Review.

-Garrido G, Saborit G, Guarga L, de Pando T, Umbria M, Oriol A, Feliu A, Pontes C, Vallano A. Evolution of Pharmacological Treatments and Associated Costs for Multiple Myeloma in the Public Healthcare System of Catalonia: A Retrospective Observational Study. Cancers. 2023; 15(22):5338. DOI:10.3390/cancers15225338. PMID:38001598. IF:4,500 (Q1/3D). Document type: Article.

-Gomis M, Perez SM, Lopez AD, Loidi VB, Lopez LL, Cruz RP, Bafalluy M. Does an eHealth Intervention Reduce Complications and Healthcare Resources? A mHeart Single-Center Randomized-Controlled Trial. Journal of Cardiovascular Development and Disease. 2023; 10(2):77. DOI:10.3390/jcdd10020077. PMID:36826572. IF:2,400 (Q2/5D). Document type: Article.

-González CGR, Vega EC, Martínez SV, Minero MV, Urbón JMG, Manzorro ÁG, Martínez EFG, Sacristán SC, Santiago EB, Alonso AH, Paredes PMG, Sáez MS; DAPTOMISE Study Group (DAPTOMIcina: eStudio de su uso clínico en España). A critical view on the current use of daptomycin in Spain: The daptomise study. J Infect Public Health. 2023; 16(7):1115-1122. DOI: 10.1016/j.jiph.2023.05.008. PMID: 37220712. IF:4,700 (Q1/1D). Document type: Article.

-Juanes A, Ruiz J, Puig M, Blazquez M, Gilabert A, Lopez L, Baena MI, Guiu JM, Mangues MA. The Effect of the Drug-Related Problems Prevention Bundle on Early Readmissions in Patients From the Emergency Department: A Randomized Clinical Trial. ANNALS OF PHARMACOTHERAPY. 2023; 57(9). DOI:10.1177/10600280221143237. PMID:36539949. IF:2,300 (Q3/6D). Document type: Article.

-Mir JF, Rodriguez C, Estrada M, de Gamarra EF, Mangues MA, Bagaria G, Riera P. An Integrated Multidisciplinary Circuit Led by Hospital and Community Pharmacists to Implement Clopidogrel Pharmacogenetics in Clinical Practice. Pharmacy. 2023; 11(2):76. DOI:10.3390/pharmacy11020076. PMID:37104082. IF:2,000 (Q3/7D). Document type: Article.

-Navarro AJ, Ramos JR, Alquezar A, Gil SO, Baena SP, Andreu OM. Association between polypharmacy and mortality in patients aged over 64 years attended in hospital emergency departments: results of the EDEN project. Emergencias. 2023; 35(3). IF:5,400 (Q1/1D). Document type: Letter.

-Nezvalova K, Langebrake C, Bauters T, Moreno M-E, Ahnfelt E, Ekelund H, Domingos V, Pires V, Bonnin A, Bojanic I, Cabrerizo Y, Terwel S, Tam A. Implementation and operational management of marketed chimeric antigen receptor T cell (CAR-T Cell) therapy-a guidance by the GoCART Coalition Pharmacist Working Group. BONE MARROW TRANSPLANTATION. 2023; 58(10). DOI:10.1038/s41409-023-02072-7. PMID:37528237. IF:4,500 (Q1/2D). Document type: Article.

-Plaza V, Alobid I, Álvarez C, Blanco M, Ferreira J, García G, Gómez A, Garín N, Gómez F, Hidalgo A, Korta J, Molina J, Pellegrini FJ, Plaza J, Praena M, Quirce S, Sanz J, Soto JG. GEMA 5.3. Spanish Guideline on the Management of Asthma. Open Respiratory Archives. 2023; 5(4):100277. DOI:10.1016/j.opresp.2023.100277. PMID:37886027. Document type: Article.

-Ramos JR, Hernanz BC, Clemente YC, Sanchez MB, Alcon EV, Perrin M, Martin M, Pinto A, Campana JMR, Rodriguez JR, Blanco CC, Pelaez MG, Ramos HA, Ruiz JA, Serrano PS, Cerezuela MM, Parraga LP, Borrego A, Fernandez BS, Camacho JMR, Campmany MP, Blanco IM, Vecina ST, Galmes CN, Marco JP. Pharmacist care in hospital emergency departments: a consensus paper from the Spanish hospital pharmacy and emergency medicine associations. Emergencias. 2023; 35(3). PMID:37350603. IF:5,400 (Q1/1D). Document type: Article.

-Ramos JR, Hernanz BC. [Translated article] Pharmaceutical care in emergency department [Atención Farmacéutica en los servicios de urgencias]. Farmacia Hospitalaria. 2023; 47(3):T97-T99. DOI:10.1016/j.farma.2023.05.001. PMID:37236837. IF:1,000 (Q4/9D). Document type: Editorial Material.

-Ramos JR, Puig MS, Vinardell LL, Pons M, Carbo EG, Campmany MP, Mangues MA, Borrego AJ. Usefulness of ICD-10 diagnosis triggers to identify adverse drug events in emergency care. Farmacia Hospitalaria. 2023; 47(2). DOI:10.1016/j.farma.2023.01.001. PMID:36702641. IF:1,000 (Q4/9D). Document type: Article.

-Ramos JR, Puig MS, Vinardell LL, Ponsa M, Carbo EG, Campmany MP, Mangues MA, Borrego AJ. [Translated article] Usefulness of ICD-10 diagnostic triggers to identify adverse drug events in emergency care. Farmacia Hospitalaria. 2023; 47(2):T75-T79. DOI:10.1016/j.farma.2023.02.004. PMID:36934016. IF:1,000 (Q4/9D). Document type: Article.

-Ruiz Ramos J, Calderón Hernanz B. Pharmaceutical care in the emergency department. Farm Hosp. 2023 May-Jun;47(3):97-99. DOI: 10.1016/j.farma.2023.02.006. PMID: 37088598. IF:1,000 (Q4/9D). Document type: Editorial Material.

-Redondo S, De Dios A, Gomis M, Esquirol A, Aso O, Triquell M, Moreno ME, Riba M, Ruiz J, Blasco A, Tobajas E, Gonzalez I, Sierra J, Martino R, Garcia I. Feasibility of a New Model of Care for Allogeneic Stem Cell Transplantation Recipients Facilitated by eHealth: The MY-Medula Pilot Study. Transplantation And Cellular Therapy. 2023; 29(6):385.e1-385.e8. DOI:10.1016/j.jtct.2023.03.016. PMID:36948273. IF:3,600 (Q1/3D). Document type: Article.

-Ruiz J, Escolà L, Monje AE, Herrera S, Rivera A. The Interventions and Challenges of Antimicrobial Stewardship in the Emergency Department. Antibiotics-Basel. 2023; 12(10):1522. DOI:10.3390/antibiotics12101522. PMID:37887223. IF:4,300 (Q1/2D). Document type: Review.

-Ruiz J, Gras L, Ramirez P. Antimicrobial Pharmacokinetics and Pharmacodynamics in Critical Care: Adjusting the Dose in Extracorporeal Circulation and to Prevent the Genesis of Multiresistant Bacteria. Antibiotics-Basel. 2023; 12(3):475. DOI:10.3390/antibiotics12030475. PMID:36978342. IF:4,300 (Q1/2D). Document type: Review.

-Ruiz J, Herrera S, Rivera MA, Monje AE, Hernández H, Pereia CS, Martinez YM, Puig M. Programa de optimización de antibioterapia en infección urinaria por cepas multirresistentes en el servicio de urgencias. Revista Espanola de Quimioterapia. 2023; 36(5). DOI:10.37201/req/009.2023. PMID:37458335. IF:1,900 (Q3/7D). Document type: Article.

-Ruiz J, Monje AE, Medina D, Herrera S, Hernandez H, Rivera MA, Pereira CS, Puig M. PREDICTION OF MULTIDRUG-RESISTANT BACTERIA IN URINARY TRACT INFECTIONS IN THE EMERGENCY DEPARTMENT. JOURNAL OF EMERGENCY MEDICINE. 2023; 65(1). DOI:10.1016/j.jemermed.2023.04.004. PMID:37385920. IF:1,200 (Q3/7D). Document type: Article.

-Ruiz J, Ramírez P. Antimicrobial stewardship programs in the intensive care unit in patients with infections caused by multidrug-resistant gram-negative bacilli. Medicina Intensiva. 2023; 47(2). DOI:10.1016/j.medin.2022.07.007. PMID:36319534. IF:2,700 (Q2/5D). Document type: Article.

-Ruiz J. Drug-related problems as reason for emergency department visit: 3 years of the FARM-URG registry. International Journal Of Pharmacy Practice. 2023; 31(4). DOI:10.1093/ijpp/riad022. PMID:37029923. IF:1,500 (Q3/8D). Document type: Article.

-Vallez L, Gasó I, Marcos Á, Garrido G, Riera A, Plaza A, Martinez C, Mangues MA, Corominas H. Are all JAK inhibitors for the treatment of rheumatoid arthritis equivalent? An adjusted indirect comparison of the efficacy of tofacitinib, baricitinib, upadacitinib, and filgotinib. CLINICAL RHEUMATOLOGY. 2023; DOI:10.1007/s10067-023-06787-2. PMID:37831336. IF:2,900 (Q2/4D). Document type: Article.

-Walsh DJ, Kantilal K, Herledan C, Nightingale G, Slavova V, Moreno ME, Penn S, Chien J, Kantilal K. Medication assessment in older adults with cancer-Current practices in clinical pharmacy. Journal of Geriatric Oncology. 2023; 14(5):101531. DOI:10.1016/j.jgo.2023.101531. PMID:37211515. IF:3,000 (Q2/5D). Document type: Article.

Publicaciones 2022

(JIF 2022)

Chazan G, Jupp J, Bauters T, Duncan N, Weddle KJ, Nomura H, O’Connor S, Chan A, Alkhudair N, Alsamrani M, Buie LW, Chambers P, Chieh TW, DeRemer DL, Duvivier F, Katabalo D, McFarlane T, Mckavanagh D, Mensah K, Martinez EM, Rowan G, Sae M, Tadesse TA, Weru I, Alexander M. Impact of coronavirus of 2019 on the delivery of pharmacy services to patients with cancer: An international survey of oncology pharmacy practitioners. JOURNAL OF ONCOLOGY PHARMACY PRACTICE. 2022; 28(8):10781552211048892. DOI:10.1177/10781552211048892. PMID:34693814. IF:1,3 (Q4/10D). Document type: Article.
Conejo I, Mas N, Riera P, Cardenete J, Puig R, Blanco MR, De Pourcq JT. Hernia enlargement and pancreatitis in a patient with short bowel syndrome treated with teduglutide. Nutricion Hospitalaria. 2022; 39(1):03879. DOI:10.20960/nh.03879. PMID:34903028. IF:1,2 (Q4/9D). Document type: Article.
Crespo A, Curto E, Garin N, Piera A, Plaza V, Sanchez S. Criterios de derivación del paciente asmático adulto entre neumología, atención primaria y urgencias. Ed: Hospital de la Santa Creu i Sant Pau. 2022. Document type: Practice guideline.
Crespo A, Curto E, Garin N, Piera A, Plaza V, Sanchez S. Guía Rápida para el Manejo del asma. Ed: Hospital de la Santa Creu i Sant Pau. 2022. Document type: Practice guideline.
De Dios A, Masip M, Pagès N, Riera P, Mateo MG, Del Mar M, Mangues MA, Gomis M. Desarrollo de una intervención mHealth para rediseñar la ruta asistencial de las personas que viven con VIH: Estudio cualitativo. Farmacia Hospitalaria. 2022; 46. DOI:10.7399/fh.13249. PMID:36520560. Document type: Article.
Galassi M, Moreno-Martínez ME. Chapter 41 Role of The EBMT/EHA CAR-T Cell Handbook. Ed Nicolaus Kröger, John Gribben, ChristianChabannon, IbrahimYakoub-Agha, Hermann Einsele. ISBN 978-3-030-94352-3 ISBN 978-3-030-94353-0 (eBook) https://doi.org/10.1007/978-3-030-94353-0. Document type: Book chapter.
Garin N (Comité Ejecutivo). Guía Española para el Manejo del Asma (GEMA 5.2). Editorial luzan5. Madrid 2022. ISBN: 978-84-19069-13-9. Document type: Practice guideline.
Garin N (Coordinator, co-author). Boletín Grupo NEUMO: Actualización en patología respiratòria. Vol 2. n1, Vol 2. n2, Vol 2. n3, Vol 2. N4. 2022. ISSN: 2792-8365.
Gutierrez JM, Arenere M, Fernandez E, Fernandez A, Gonzalez S, Nicolas J, Rodriguez ME, Sanchez E. PAUSATE Study: Prevalence and appropriateness of the use of antimicrobials in Spanish hospitals. Farmacia Hospitalaria. 2022; 46(5). DOI:10.7399/fh.13152. PMID:36183227. Document type: Article.
Mangues MA. La Metamorfosis de la Farmàcia de Sant Pau (1950-2022). Capítol del llibre “ Hospital de Sant Pau: Història i Vivències 1965-2009”. Associació Amics i Alumnes Hospital de Sant Pau. P. 323-335. 2022. ISBN: 977-84-09-41086-6. Document type: Book chapter.
Mas N, Ruiz J, Juanes AM, Agra I, Vega L, López L, Puig M, Mangues MA. Risk factors associated with emergency service re-visits in frailty diabetic patients who consult for hypoglycaemia. Medicina De Familia-Semergen. 2022; 48(3). DOI:10.1016/j.semerg.2021.09.011. PMID:34848135. Document type: Article.
Medina D, Riera P, Pages N, Masip M, Lopez A, Vilarrasa E, Puig L. A cohort study of guselkumab in the treatment of psoriasis refractory to previous biologic therapies: effectiveness, safety and adherence. International Journal of Clinical Pharmacy. 2022; 44(3). DOI:10.1007/s11096-022-01400-z. PMID:35380392. IF:2,4 (Q3/8D). Document type: Article.
Moreno E, de la Serna J, Escudero V, Hernandez JA, Sanchez M, Sanchez R. Cost-utility analysis of venetoclax in combination with obinutuzumab as first-line treatment of chronic lymphocytic leukaemia in Spain. Farmacia Hospitalaria. 2022; 46(3). DOI:10.7399/fh.11829. PMID:36183205. Document type: Article.
Moreno Martínez ME, Rodríguez-Lescure A, Felip Font E, Delgado Sánchez O (Coordinators). 10 desafíos comunes para farmacia hospitalaria y oncología. Coordinadores: Libro. ISBN: 978-84-09-38417-4. Depósito legal: M-6987-2022. Document type: Book chapter.
Morillo R, Collado R, Arrondo A, Domínguez M, Fernández A, González E, Gutiérrez E, Linares A, de los Ángeles Parro M, Rodríguez MÁ, Gomis M. Guía de implementación de la atención farmacéutica mediante Telefarmacia para profesionales y pacientes. Farmacia Hospitalaria. 2022; 46. DOI:10.7399/fh.13260. PMID:36520566. Document type: Article.
Riera P, Sole N, Suarez JC, Lopez PA, Fonts N, Rodriguez N, de Gamarra EF, Moran I. Drug-drug interactions in an intensive care unit and comparison of updates in two databases. Farmacia Hospitalaria. 2022; 46(5). DOI:10.7399/fh.13180. PMID:36183229. Document type: Article.
Rodríguez F, Caruana P, De la Fuente N, Español P, Gámez M, Balart J, Llurba E, RAMON N, Ruiz R, Martín C, Corchero JL, Céspedes MV. Nano-Based Approved Pharmaceuticals for Cancer Treatment: Present and Future Challenges. Biomolecules. 2022; 12(6):784. DOI:10.3390/biom12060784. PMID:35740909. IF:5,5 (Q1/3D). Document type: Review.
Rodriguez L, Rodriguez A, Mejias M, Beobide I, Juanes AM, Saavedra V, Carrion IM. Validation protocol of the LESS-CHRON deprescription tool in multimorbidity patients. LESS-CHRON-VALIDATION Project. Farmacia Hospitalaria. 2022; 46(5). DOI:10.7399/fh.13268. PMID:36183233. Document type: Article.
Ruiz J, Herrera S, Lopez L, Juanes A, Puig M, Mangues MA. Cefepime Dosing Requirements in Elderly Patients Attended in the Emergency Rooms. Dose-Response. 2022; 20(1):15593258221078393. DOI:10.1177/15593258221078393. PMID:35237115. IF:2,5 (Q3/6D). Document type: Article.
Ruiz J, Juanes A, Puig M, Blazquez M, Lopez L, Gilabert A, Guiu JM, Mangues MA. Cost-effectiveness analysis of implementing a secondary prevention programme in those patients who visited an emergency department for drug-related problems. International Journal Of Pharmacy Practice. 2022; 30(5). DOI:10.1093/ijpp/riac061. PMID:35849346. Document type: Article.
Ruiz J, López L, Juanes A, Riera A, Puig M, Mangues MA. Risk factors for emergency department revisit in elderly patients with gastrointestinal bleeding secondary to anticoagulant therapy. EUROPEAN JOURNAL OF HOSPITAL PHARMACY. 2022; 29(5). DOI:10.1136/ejhpharm-2020-002426. IF:1,7 (Q4/9D). Document type: Article.
Serda PC, Teres R, Sebio A, Bague S, Orellana R, Moreno ME, Riba M, Lopez A. Single-Center Experience with Trabectedin for the Treatment of Non-L-sarcomas. ADVANCES IN THERAPY. 2022; 39(4). DOI:10.1007/s12325-022-02051-2. PMID:35129790. IF:3,8 (Q2/4D). Document type: Article.
Serra S, López L, Sisinni L, Serna JV, Martínez L, Fernández de Gamarra E, de la Calle O, Badell I. Chronic hypogammaglobulinemia after allogeneic stem cell transplantation and their treatment with subcutanaeos inmunoglobulin in pediatric patients. ANALES DE PEDIATRIA. 2022; 97(2). DOI:10.1016/j.anpedi.2021.08.011. PMID:35869014. IF:2,1 (Q3/6D). Document type: Article.
Trigueros JA, Garin N, Baloira A, Aceituno S, Calvo A, Prades M, Touron C, Martinez A, Torres C. Cost-Effectiveness Analysis of Triple Therapy with Budesonide/ Glycopyrronium/ Formoterol Fumarate versus Dual Therapy in Patients with Chronic Obstructive Pulmonary Disease in Spain. International Journal of Chronic Obstructive Pulmonary Disease. 2022; 17. DOI:10.2147/COPD.S384591. PMID:36411773. IF:2,8 (Q3/7D). Document type: Article.

Publicaciones 2021

Castro V, Garin N, Jaen A, Casado JL, Leal L, Cenoz S, Fuster MJ. Recreational Drug Use in People Living with HIV in Spain: Factors Associated with Drug Use and the Impact on Clinical Outcomes. AIDS AND BEHAVIOR. 2021; 25(12). DOI:10.1007/s10461-021-03271-3. PMID:33932187. IF:4,852.
Castro V, Garin N, Jaen A, Cenoz S, Galindo MJ, Apodaca MJFR. Prevalence, beliefs and impact of drug-drug interactions between antiretroviral therapy and illicit drugs among people living with HIV in Spain. PLoS One. 2021; 16(11):e0260334. DOI:10.1371/journal.pone.0260334. PMID:34797882. IF:3,752.
Corominas H, Castellvi I, Diaz C, Matas L, de la Rosa D, Mangues MA, Moya P, Pomar V, Benito N, Moga E, Hernandez N, Casademont J, Domingo P. Sarilumab (IL-6R antagonist) in critically ill patients with cytokine release syndrome by SARS-CoV2. MEDICINE. 2021; 100(19):e25923. DOI:10.1097/MD.0000000000025923. PMID:34106658. IF:1,817.
Corominas H, Castellvi I, Pomar V, Antonijoan R, Mur I, Matas L, Gich I, de Benito N, Laiz A, Castillo D, Villamarin L, Filella D, Mill AM, Quijada MA, Puig M, Casademont J, Domingo P. Effectiveness and safety of intravenous tocilizumab to treat COVID-19-associated hyperinflammatory syndrome: Covizumab-6 observational cohort. CLINICAL IMMUNOLOGY. 2021; 223:108631. DOI:10.1016/j.clim.2020.108631. PMID:33189888. IF:10,190.
Falgas A, Pallares V, Unzueta U, Nunez Y, Sierra J, Gallardo A, Alba L, Mangues MA, Alamo P, Villaverde A, Vazquez E, Mangues R, Casanova I. Specific Cytotoxic Effect of an Auristatin Nanoconjugate Towards CXCR4(+) Diffuse Large B-Cell Lymphoma Cells. International Journal of Nanomedicine. 2021; 16. DOI:10.2147/IJN.S289733. PMID:33716502. IF:7,033.
Garin N, Sole N, Lucas B, Matas L, Moras D, Rodrigo A, Gras L, Fonts N. Drug related problems in clinical practice: a cross-sectional study on their prevalence, risk factors and associated pharmaceutical interventions. Scientific Reports. 2021; 11(1):883. DOI:10.1038/s41598-020-80560-2. PMID:33441854. IF:4,996.
Gomis M, Perez SM, Minguell ER, Loidi VB, Lopez LL, Abarca SR, Tugas EG, Mas N, Bafalluy M. Mobile Health to Improve Adherence and Patient Experience in Heart Transplantation Recipients: The mHeart Trial. Healthcare. 2021; 9(4):463. DOI:10.3390/healthcare9040463. PMID:33919899. IF:3,160.
Hernandez MH, Juanes AM, Mila R, Mangues MA, Mestres C. The Impact of Pharmaceutical Care in Multidisciplinary Teams on Health Outcomes: Systematic Review and Meta-Analysis. Journal of the American Medical Directors Association. 2021; 22(12). DOI:10.1016/j.jamda.2021.05.0381525-8610. PMID:34228962. IF:7,802.
Ruiz J, Alcon EV, Ramos FM, Santolaya R, Tey JMG. Antimicrobial stewardship programs in emergency departments: how do we measure antimicrobial use? A systematic review. Revista Espanola de Quimioterapia. 2021; 34(6). DOI:10.37201/req/028.2021. PMID:34523327. IF:7,802.

Presentación

Principales líneas investigación

Atención farmacéutica.
Nutrición artificial.
Oncohematología.
Ensayos clínicos independientes.

Retos

Evaluar el impacto en la eficacia y seguridad de los tratamientos farmacológicos en diferentes programas de atención farmacéutica: farmacocinética clínica, educación sanitaria de los pacientes ambulatorios, reconciliación e identificación de la medicación y prevención de los problemas relacionados con la medicación.
Evaluar el impacto de la nutrición artificial en la evolución clínica de los pacientes.
Estudio de la estabilidad de citostáticos en diferentes condiciones de uso.
Predecir la respuesta al tratamiento anti-tumoral en un número de procesos tumorales.
Desarrollar inhibidores de adhesión focal, por ejemplo, agentes antitumorales.
Cooperar activamente en los ensayos clínicos independientes realizados por nuestro Instituto.

Equipo

Coordinación del grupo

FELIU RIBERA, ANNA FGS
afeliu@santpau.cat

Miembros

Producción científica

Publicaciones 2023

(JIF 2023)

Publicaciones 2022

(JIF 2022)

Chazan G, Jupp J, Bauters T, Duncan N, Weddle KJ, Nomura H, O’Connor S, Chan A, Alkhudair N, Alsamrani M, Buie LW, Chambers P, Chieh TW, DeRemer DL, Duvivier F, Katabalo D, McFarlane T, Mckavanagh D, Mensah K, Martinez EM, Rowan G, Sae M, Tadesse TA, Weru I, Alexander M. Impact of coronavirus of 2019 on the delivery of pharmacy services to patients with cancer: An international survey of oncology pharmacy practitioners. JOURNAL OF ONCOLOGY PHARMACY PRACTICE. 2022; 28(8):10781552211048892. DOI:10.1177/10781552211048892. PMID:34693814. IF:1,3 (Q4/10D). Document type: Article.
Conejo I, Mas N, Riera P, Cardenete J, Puig R, Blanco MR, De Pourcq JT. Hernia enlargement and pancreatitis in a patient with short bowel syndrome treated with teduglutide. Nutricion Hospitalaria. 2022; 39(1):03879. DOI:10.20960/nh.03879. PMID:34903028. IF:1,2 (Q4/9D). Document type: Article.
Crespo A, Curto E, Garin N, Piera A, Plaza V, Sanchez S. Criterios de derivación del paciente asmático adulto entre neumología, atención primaria y urgencias. Ed: Hospital de la Santa Creu i Sant Pau. 2022. Document type: Practice guideline.
Crespo A, Curto E, Garin N, Piera A, Plaza V, Sanchez S. Guía Rápida para el Manejo del asma. Ed: Hospital de la Santa Creu i Sant Pau. 2022. Document type: Practice guideline.
De Dios A, Masip M, Pagès N, Riera P, Mateo MG, Del Mar M, Mangues MA, Gomis M. Desarrollo de una intervención mHealth para rediseñar la ruta asistencial de las personas que viven con VIH: Estudio cualitativo. Farmacia Hospitalaria. 2022; 46. DOI:10.7399/fh.13249. PMID:36520560. Document type: Article.
Galassi M, Moreno-Martínez ME. Chapter 41 Role of The EBMT/EHA CAR-T Cell Handbook. Ed Nicolaus Kröger, John Gribben, ChristianChabannon, IbrahimYakoub-Agha, Hermann Einsele. ISBN 978-3-030-94352-3 ISBN 978-3-030-94353-0 (eBook) https://doi.org/10.1007/978-3-030-94353-0. Document type: Book chapter.
Garin N (Comité Ejecutivo). Guía Española para el Manejo del Asma (GEMA 5.2). Editorial luzan5. Madrid 2022. ISBN: 978-84-19069-13-9. Document type: Practice guideline.
Garin N (Coordinator, co-author). Boletín Grupo NEUMO: Actualización en patología respiratòria. Vol 2. n1, Vol 2. n2, Vol 2. n3, Vol 2. N4. 2022. ISSN: 2792-8365.
Gutierrez JM, Arenere M, Fernandez E, Fernandez A, Gonzalez S, Nicolas J, Rodriguez ME, Sanchez E. PAUSATE Study: Prevalence and appropriateness of the use of antimicrobials in Spanish hospitals. Farmacia Hospitalaria. 2022; 46(5). DOI:10.7399/fh.13152. PMID:36183227. Document type: Article.
Mangues MA. La Metamorfosis de la Farmàcia de Sant Pau (1950-2022). Capítol del llibre “ Hospital de Sant Pau: Història i Vivències 1965-2009”. Associació Amics i Alumnes Hospital de Sant Pau. P. 323-335. 2022. ISBN: 977-84-09-41086-6. Document type: Book chapter.
Mas N, Ruiz J, Juanes AM, Agra I, Vega L, López L, Puig M, Mangues MA. Risk factors associated with emergency service re-visits in frailty diabetic patients who consult for hypoglycaemia. Medicina De Familia-Semergen. 2022; 48(3). DOI:10.1016/j.semerg.2021.09.011. PMID:34848135. Document type: Article.
Medina D, Riera P, Pages N, Masip M, Lopez A, Vilarrasa E, Puig L. A cohort study of guselkumab in the treatment of psoriasis refractory to previous biologic therapies: effectiveness, safety and adherence. International Journal of Clinical Pharmacy. 2022; 44(3). DOI:10.1007/s11096-022-01400-z. PMID:35380392. IF:2,4 (Q3/8D). Document type: Article.
Moreno E, de la Serna J, Escudero V, Hernandez JA, Sanchez M, Sanchez R. Cost-utility analysis of venetoclax in combination with obinutuzumab as first-line treatment of chronic lymphocytic leukaemia in Spain. Farmacia Hospitalaria. 2022; 46(3). DOI:10.7399/fh.11829. PMID:36183205. Document type: Article.
Moreno Martínez ME, Rodríguez-Lescure A, Felip Font E, Delgado Sánchez O (Coordinators). 10 desafíos comunes para farmacia hospitalaria y oncología. Coordinadores: Libro. ISBN: 978-84-09-38417-4. Depósito legal: M-6987-2022. Document type: Book chapter.
Morillo R, Collado R, Arrondo A, Domínguez M, Fernández A, González E, Gutiérrez E, Linares A, de los Ángeles Parro M, Rodríguez MÁ, Gomis M. Guía de implementación de la atención farmacéutica mediante Telefarmacia para profesionales y pacientes. Farmacia Hospitalaria. 2022; 46. DOI:10.7399/fh.13260. PMID:36520566. Document type: Article.
Riera P, Sole N, Suarez JC, Lopez PA, Fonts N, Rodriguez N, de Gamarra EF, Moran I. Drug-drug interactions in an intensive care unit and comparison of updates in two databases. Farmacia Hospitalaria. 2022; 46(5). DOI:10.7399/fh.13180. PMID:36183229. Document type: Article.
Rodríguez F, Caruana P, De la Fuente N, Español P, Gámez M, Balart J, Llurba E, RAMON N, Ruiz R, Martín C, Corchero JL, Céspedes MV. Nano-Based Approved Pharmaceuticals for Cancer Treatment: Present and Future Challenges. Biomolecules. 2022; 12(6):784. DOI:10.3390/biom12060784. PMID:35740909. IF:5,5 (Q1/3D). Document type: Review.
Rodriguez L, Rodriguez A, Mejias M, Beobide I, Juanes AM, Saavedra V, Carrion IM. Validation protocol of the LESS-CHRON deprescription tool in multimorbidity patients. LESS-CHRON-VALIDATION Project. Farmacia Hospitalaria. 2022; 46(5). DOI:10.7399/fh.13268. PMID:36183233. Document type: Article.
Ruiz J, Herrera S, Lopez L, Juanes A, Puig M, Mangues MA. Cefepime Dosing Requirements in Elderly Patients Attended in the Emergency Rooms. Dose-Response. 2022; 20(1):15593258221078393. DOI:10.1177/15593258221078393. PMID:35237115. IF:2,5 (Q3/6D). Document type: Article.
Ruiz J, Juanes A, Puig M, Blazquez M, Lopez L, Gilabert A, Guiu JM, Mangues MA. Cost-effectiveness analysis of implementing a secondary prevention programme in those patients who visited an emergency department for drug-related problems. International Journal Of Pharmacy Practice. 2022; 30(5). DOI:10.1093/ijpp/riac061. PMID:35849346. Document type: Article.
Ruiz J, López L, Juanes A, Riera A, Puig M, Mangues MA. Risk factors for emergency department revisit in elderly patients with gastrointestinal bleeding secondary to anticoagulant therapy. EUROPEAN JOURNAL OF HOSPITAL PHARMACY. 2022; 29(5). DOI:10.1136/ejhpharm-2020-002426. IF:1,7 (Q4/9D). Document type: Article.
Serda PC, Teres R, Sebio A, Bague S, Orellana R, Moreno ME, Riba M, Lopez A. Single-Center Experience with Trabectedin for the Treatment of Non-L-sarcomas. ADVANCES IN THERAPY. 2022; 39(4). DOI:10.1007/s12325-022-02051-2. PMID:35129790. IF:3,8 (Q2/4D). Document type: Article.
Serra S, López L, Sisinni L, Serna JV, Martínez L, Fernández de Gamarra E, de la Calle O, Badell I. Chronic hypogammaglobulinemia after allogeneic stem cell transplantation and their treatment with subcutanaeos inmunoglobulin in pediatric patients. ANALES DE PEDIATRIA. 2022; 97(2). DOI:10.1016/j.anpedi.2021.08.011. PMID:35869014. IF:2,1 (Q3/6D). Document type: Article.
Trigueros JA, Garin N, Baloira A, Aceituno S, Calvo A, Prades M, Touron C, Martinez A, Torres C. Cost-Effectiveness Analysis of Triple Therapy with Budesonide/ Glycopyrronium/ Formoterol Fumarate versus Dual Therapy in Patients with Chronic Obstructive Pulmonary Disease in Spain. International Journal of Chronic Obstructive Pulmonary Disease. 2022; 17. DOI:10.2147/COPD.S384591. PMID:36411773. IF:2,8 (Q3/7D). Document type: Article.

Publicaciones 2021

Castro V, Garin N, Jaen A, Casado JL, Leal L, Cenoz S, Fuster MJ. Recreational Drug Use in People Living with HIV in Spain: Factors Associated with Drug Use and the Impact on Clinical Outcomes. AIDS AND BEHAVIOR. 2021; 25(12). DOI:10.1007/s10461-021-03271-3. PMID:33932187. IF:4,852.
Castro V, Garin N, Jaen A, Cenoz S, Galindo MJ, Apodaca MJFR. Prevalence, beliefs and impact of drug-drug interactions between antiretroviral therapy and illicit drugs among people living with HIV in Spain. PLoS One. 2021; 16(11):e0260334. DOI:10.1371/journal.pone.0260334. PMID:34797882. IF:3,752.
Corominas H, Castellvi I, Diaz C, Matas L, de la Rosa D, Mangues MA, Moya P, Pomar V, Benito N, Moga E, Hernandez N, Casademont J, Domingo P. Sarilumab (IL-6R antagonist) in critically ill patients with cytokine release syndrome by SARS-CoV2. MEDICINE. 2021; 100(19):e25923. DOI:10.1097/MD.0000000000025923. PMID:34106658. IF:1,817.
Corominas H, Castellvi I, Pomar V, Antonijoan R, Mur I, Matas L, Gich I, de Benito N, Laiz A, Castillo D, Villamarin L, Filella D, Mill AM, Quijada MA, Puig M, Casademont J, Domingo P. Effectiveness and safety of intravenous tocilizumab to treat COVID-19-associated hyperinflammatory syndrome: Covizumab-6 observational cohort. CLINICAL IMMUNOLOGY. 2021; 223:108631. DOI:10.1016/j.clim.2020.108631. PMID:33189888. IF:10,190.
Falgas A, Pallares V, Unzueta U, Nunez Y, Sierra J, Gallardo A, Alba L, Mangues MA, Alamo P, Villaverde A, Vazquez E, Mangues R, Casanova I. Specific Cytotoxic Effect of an Auristatin Nanoconjugate Towards CXCR4(+) Diffuse Large B-Cell Lymphoma Cells. International Journal of Nanomedicine. 2021; 16. DOI:10.2147/IJN.S289733. PMID:33716502. IF:7,033.
Garin N, Sole N, Lucas B, Matas L, Moras D, Rodrigo A, Gras L, Fonts N. Drug related problems in clinical practice: a cross-sectional study on their prevalence, risk factors and associated pharmaceutical interventions. Scientific Reports. 2021; 11(1):883. DOI:10.1038/s41598-020-80560-2. PMID:33441854. IF:4,996.
Gomis M, Perez SM, Minguell ER, Loidi VB, Lopez LL, Abarca SR, Tugas EG, Mas N, Bafalluy M. Mobile Health to Improve Adherence and Patient Experience in Heart Transplantation Recipients: The mHeart Trial. Healthcare. 2021; 9(4):463. DOI:10.3390/healthcare9040463. PMID:33919899. IF:3,160.
Hernandez MH, Juanes AM, Mila R, Mangues MA, Mestres C. The Impact of Pharmaceutical Care in Multidisciplinary Teams on Health Outcomes: Systematic Review and Meta-Analysis. Journal of the American Medical Directors Association. 2021; 22(12). DOI:10.1016/j.jamda.2021.05.0381525-8610. PMID:34228962. IF:7,802.
Ruiz J, Alcon EV, Ramos FM, Santolaya R, Tey JMG. Antimicrobial stewardship programs in emergency departments: how do we measure antimicrobial use? A systematic review. Revista Espanola de Quimioterapia. 2021; 34(6). DOI:10.37201/req/028.2021. PMID:34523327. IF:7,802.

GRUPOS ASOCIADOS

Farmacia

Principales líneas investigación

Retos

Coordinación del grupo

Miembros

Publicaciones 2023

Publicaciones 2022

Publicaciones 2021

Principales líneas investigación

Retos

Coordinación del grupo

Miembros

Publicaciones 2023

Publicaciones 2022

Publicaciones 2021

Institut de Recerca de l’Hospital de la Santa Creu i Sant Pau