A multidisciplinary team of researchers from the University of Calgary, the Sant Pau Research Institute (IIB Sant Pau) and the Institute of Biomedical Research of Barcelona (IIBB-CSIC), and the Polytechnic University of Catalonia – BarcelonaTech (UPC) has identified one of the molecular mechanisms responsible for cardiac alternans, an alteration of the heart rhythm that facilitates the induction of ventricular fibrillation, a potentially lethal type of arrhythmia. This discovery, published today, February 19, in the journal Circulation Research (AHA Journals), opens the door to the development of new pharmacological treatments.