Sant Pau - Institut de Recerca

Main lines of research

The medical approach to hormonally induced or controlled gynaecological diseases: Endometriosis, fibroids, menstrual disorders.
Explore non-contraceptive benefits of hormonal contraception.
Develop tools for the early diagnosis and management of heavy menstrual bleeding.
Polycystic Ovarian Syndrome, premature and normal menopause, amenorrhea.

Challenges

To develop and test in the clinical settings easy tools to identify heavy menstrual bleeding.
To evaluate the impact of the different contraceptive methods on the characteristics of menstruation.
To evaluate the cost/benefit ratio of using non-surgical approaches for hormonemediated organic gynecologic diseases.
To build up a nationwide registry of Premature Ovarian insufficiency (POI).

Group coordination

CALAF ALSINA, JOAQUIM UAB
jcalaf@santpau.cat

Members

Estadella Tarriel, Josep Ramon FGS
Guinot Gasull, Misericordia FGS
Mayordomo Bofill, Isabet
Miarons Ferre, Bruna FGS
Perello Capo, Josep FGS

Publications 2023

(JIF 2022)

-Calaf J, Cano A, Guañabens N, Palacios S, Cancelo MJ, Castelo C, Larrainzar R, Neyro JL, Nogues X, Diez A. Sequential management of postmenopausal health and osteoporosis: An update. MATURITAS. 2023; 177:107846. DOI:10.1016/j.maturitas.2023.107846. PMID:37738717. IF:4,900 (Q1/2D). Document type: Review.

-Estadella J, Perelló J, Muñoz R. Update on the possibilities of hormonal medical treatment for heavy menstrual bleeding. Clinica E Investigacion En Ginecologia Y Obstetricia. 2023; 50(1):100819. DOI:10.1016/j.gine.2022.100819. Document type: Review.

-Perelló J, Estadella J, Gich I, Bailón M, Llurba E, Calaf J. Bleeding profile and safety of a levonorgestrel 13.5 mg intrauterine device versus Nova T copper 380 mm(2) intrauterine device: Results of a 3-year, single-center, randomized phase 4 study. CONTRACEPTION. 2023; 127:110127. DOI:10.1016/j.contraception.2023.110127. PMID:37487868. IF:2,900 (Q2/5D). Document type: Article.

-Perelló J, Quílez JC, Gutiérrez J, Lobo P, Parra I, Cristóbal I, Andeyro M, Herrero M, Rius J, Calaf J. Use of Contraceptive Methods Among Women in the General Population and Female Gynecologists in Spain: the ELEGIAN Survey. WOMENS HEALTH REPORTS. 2023; 4(1)DOI:10.1089/whr.2023.0048. PMID:37818182. Document type: Article.

-Perelló J, Quílez JC, Lobo P, Andeyro M, Cristóbal I, Gutiérrez J, Herrero M, Parra I, Estadella J, Rius J, Calaf J. Prevalence and impact of heavy menstrual bleeding in Spain: Results of a national survey. Clinica E Investigacion En Ginecologia Y Obstetricia. 2023; 50(3):100877. DOI:10.1016/j.gine.2023.100877. Document type: Article.

-Perello J, Rius J, Andeyro M, Calaf J. Sensitivity to Change of the SAMANTA Questionnaire, a Heavy Menstrual Bleeding Diagnostic Tool, After 1 Year of Hormonal Treatment. JOURNAL OF WOMENS HEALTH. 2023; 32(2)DOI:10.1089/jwh.2022.0155. PMID:36576860. IF:3,500 (Q1/2D). Document type: Article.

-Quílez JC, Perelló J, Parra I, Andeyro M, Cristóbal I, Gutiérrez J, Herrero M, Lobo P, Rius J. Desarrollo de una herramienta de evaluación objetiva de la habilidad técnica en la inserción de dispositivos intrauterinos liberadores de levonorgestrel con sistema de inserción Evoinserter®. Progresos De Obstetricia Y Ginecologia. 2023; 66(3) Document type: Article.

-Sanger N, Menabrito M, Sardo AD, Estadella J, Verguts J. Fertility preservation counselling for women with endometriosis: a European online survey. ARCHIVES OF GYNECOLOGY AND OBSTETRICS. 2023; 307(1)DOI:10.1007/s00404-022-06616-y. PMID:35829767. IF:2,600 (Q3/6D). Document type: Article.

-Silva AL, Catherino WH, Estrade JP, Koga K, Singh SS, Vannuccini S, Yang X, Lahav A, Caetano C, Calaf J. The HOPE study: evaluating the impact of an online educational resource for heavy menstrual bleeding on the patient-physician dynamic. WOMEN & HEALTH. 2023; 63(5)DOI:10.1080/03630242.2023.2220806. PMID:37291687. IF:1,600 (Q2/5D). Document type: Article.

-von S, Bauerfeind A, Becker K, Franke C, Fruzzetti F, Calaf J, Keck C, Heinemann K. NOMAC-E2 shows a better contraceptive effectiveness than LNG combined oral contraceptives in women under 25: real-world PRO-E2 study. GYNECOLOGICAL ENDOCRINOLOGY. 2023; 39(1):2162036. DOI:10.1080/09513590.2022.2162036. PMID:36617423. IF:2,000 (Q3/8D). Document type: Article.

Publications 2022

(JIF 2022)

Blanch L, Simó M, Vanrell C, Parés P, Dosouto C, Porta O, Estadella J. Why do we still perform hysteriscopies in the Operating Room?. World Journal of Gynecology & Women’s Health. 2022; (5) 4: 1-4. DOI:10.33552/WJGWH.2022.05.000618. Document type: Article.
Capítulo: ESTRÓGENOS: LA GÉNESIS DEL TROMBOEMBOLISMO. In: WHC Exeltis Day. Madrid: Canal Editorial, 2022. ISBN:978-84-18568-91-6. Document type: Book chapter.
Capo JP, Gonzalez GL, Rius J, Alsina JC. Real-world satisfaction and menstrual bleeding pattern with available LNG-IUD among Spanish young women. EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE. 2022; 27(6). DOI:10.1080/13625187.2022.2112562. PMID:36148980. IF:1,7 (Q4/9D). Document type: Article.
Fidecicchi T, Fruzzetti F, Lasa L, Calaf J. COVID-19, gender and estroprogestins, what do we know?. EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE. 2022; 27(1). DOI:10.1080/13625187.2021.2000959. PMID:34842025. IF:1,7 (Q4/9D). Document type: Review.
Haile L, van de Roemer N, Gemzell K, Capo JP, Lasa IL, Vannuccini S, Koch MC, Hildebrandt T, Calaf J. The global pandemic and changes in women’s reproductive health: an observational study. EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE. 2022; 27(2). DOI:10.1080/13625187.2021.2024161. PMID:35040737. IF:1,7 (Q4/9D). Document type: Article.
Mendoza N, Ramirez I, de la Viuda E, Coronado P, Baquedano L, Llaneza P, Nieto V, Otero B, Sanchez S, de Frutos VA, Andraca L, Barriga P, Benitez Z, Bombas T, Cancelo MJ, Cano A, Branco CC, Correa M, Doval JL, Fasero M, Fiol G, Garello NC, Genazzani AR, Gomez AI, Gomez MA, Gonzalez S, Goulis DG, Guinot M, Hernandez LR, Herrero S, Iglesias E, Jurado AR, Lete I, Lubian D, Martinez M, Nieto A, Nieto L, Palacios S, Pedreira M, Perez E, Pla MJ, Presa J, Quereda F, Ribes M, Romero P, Roca B, Sanchez A, Sanchez R, Santaballa A, Santamaria A, Simoncini T, Tinahones F, Calaf J. Eligibility criteria for Menopausal Hormone Therapy (MHT): a position statement from a consortium of scientific societies for the use of MHT in women with medical conditions. MHT Eligibility Criteria Group. MATURITAS. 2022; 166. DOI:10.1016/j.maturitas.2022.08.008. PMID:36081216. IF:4,9 (Q1/2D). Document type: Review/Practice guideline.
Perello J, Pujol P, Perez M, Artes M, Calaf J. Heavy Menstrual Bleeding-Visual Analog Scale, an Easy-to-Use Tool for Excessive Menstrual Blood Loss That Interferes with Quality-of-Life Screening in Clinical Practice. WOMENS HEALTH REPORTS. 2022; 3(1). DOI:10.1089/whr.2021.0139. PMID:35651998. Document type: Article.
Singh SS, Alsina JC, Vannuccini S, Koga K, Silva AL, Yang X, Estrade JP, Catherino W. Clinical perspectives on the menstrual pictogram for the assessment of heavy menstrual bleeding. Human Reproduction Open. 2022; 2022(4):hoac048. DOI:10.1093/hropen/hoac048. PMID:36382010. IF:8,3 (Q1/1D). Document type: Editorial material.

Publications 2021

Balcells L, Fabra P, Polo A, Calaf J. Putting reproductive rights into practice. The profile of the demand in a publicly sponsored ART program for single or female partner women in Catalonia. EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE. 2021; 26(4). DOI:10.1080/13625187.2021.1891410. PMID:33724129. IF:1,752.
Perello J, Tarruella JR, Calaf J. Heavy menstrual bleeding and its detection in clinical practice. MEDICINA CLINICA. 2021; 157(7). DOI:10.1016/j.medcli.2021.02.006. PMID:33840528. IF:3,200.

Introduction

Main lines of research

The medical approach to hormonally induced or controlled gynaecological diseases: Endometriosis, fibroids, menstrual disorders.
Explore non-contraceptive benefits of hormonal contraception.
Develop tools for the early diagnosis and management of heavy menstrual bleeding.
Polycystic Ovarian Syndrome, premature and normal menopause, amenorrhea.

Challenges

To develop and test in the clinical settings easy tools to identify heavy menstrual bleeding.
To evaluate the impact of the different contraceptive methods on the characteristics of menstruation.
To evaluate the cost/benefit ratio of using non-surgical approaches for hormonemediated organic gynecologic diseases.
To build up a nationwide registry of Premature Ovarian insufficiency (POI).

Team

Group coordination

CALAF ALSINA, JOAQUIM UAB
jcalaf@santpau.cat

Members

Estadella Tarriel, Josep Ramon FGS
Guinot Gasull, Misericordia FGS
Mayordomo Bofill, Isabet
Miarons Ferre, Bruna FGS
Perello Capo, Josep FGS

Scientific output

Publications 2023

(JIF 2022)

Publications 2022

(JIF 2022)

Blanch L, Simó M, Vanrell C, Parés P, Dosouto C, Porta O, Estadella J. Why do we still perform hysteriscopies in the Operating Room?. World Journal of Gynecology & Women’s Health. 2022; (5) 4: 1-4. DOI:10.33552/WJGWH.2022.05.000618. Document type: Article.
Capítulo: ESTRÓGENOS: LA GÉNESIS DEL TROMBOEMBOLISMO. In: WHC Exeltis Day. Madrid: Canal Editorial, 2022. ISBN:978-84-18568-91-6. Document type: Book chapter.
Capo JP, Gonzalez GL, Rius J, Alsina JC. Real-world satisfaction and menstrual bleeding pattern with available LNG-IUD among Spanish young women. EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE. 2022; 27(6). DOI:10.1080/13625187.2022.2112562. PMID:36148980. IF:1,7 (Q4/9D). Document type: Article.
Fidecicchi T, Fruzzetti F, Lasa L, Calaf J. COVID-19, gender and estroprogestins, what do we know?. EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE. 2022; 27(1). DOI:10.1080/13625187.2021.2000959. PMID:34842025. IF:1,7 (Q4/9D). Document type: Review.
Haile L, van de Roemer N, Gemzell K, Capo JP, Lasa IL, Vannuccini S, Koch MC, Hildebrandt T, Calaf J. The global pandemic and changes in women’s reproductive health: an observational study. EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE. 2022; 27(2). DOI:10.1080/13625187.2021.2024161. PMID:35040737. IF:1,7 (Q4/9D). Document type: Article.
Mendoza N, Ramirez I, de la Viuda E, Coronado P, Baquedano L, Llaneza P, Nieto V, Otero B, Sanchez S, de Frutos VA, Andraca L, Barriga P, Benitez Z, Bombas T, Cancelo MJ, Cano A, Branco CC, Correa M, Doval JL, Fasero M, Fiol G, Garello NC, Genazzani AR, Gomez AI, Gomez MA, Gonzalez S, Goulis DG, Guinot M, Hernandez LR, Herrero S, Iglesias E, Jurado AR, Lete I, Lubian D, Martinez M, Nieto A, Nieto L, Palacios S, Pedreira M, Perez E, Pla MJ, Presa J, Quereda F, Ribes M, Romero P, Roca B, Sanchez A, Sanchez R, Santaballa A, Santamaria A, Simoncini T, Tinahones F, Calaf J. Eligibility criteria for Menopausal Hormone Therapy (MHT): a position statement from a consortium of scientific societies for the use of MHT in women with medical conditions. MHT Eligibility Criteria Group. MATURITAS. 2022; 166. DOI:10.1016/j.maturitas.2022.08.008. PMID:36081216. IF:4,9 (Q1/2D). Document type: Review/Practice guideline.
Perello J, Pujol P, Perez M, Artes M, Calaf J. Heavy Menstrual Bleeding-Visual Analog Scale, an Easy-to-Use Tool for Excessive Menstrual Blood Loss That Interferes with Quality-of-Life Screening in Clinical Practice. WOMENS HEALTH REPORTS. 2022; 3(1). DOI:10.1089/whr.2021.0139. PMID:35651998. Document type: Article.
Singh SS, Alsina JC, Vannuccini S, Koga K, Silva AL, Yang X, Estrade JP, Catherino W. Clinical perspectives on the menstrual pictogram for the assessment of heavy menstrual bleeding. Human Reproduction Open. 2022; 2022(4):hoac048. DOI:10.1093/hropen/hoac048. PMID:36382010. IF:8,3 (Q1/1D). Document type: Editorial material.

Publications 2021

Balcells L, Fabra P, Polo A, Calaf J. Putting reproductive rights into practice. The profile of the demand in a publicly sponsored ART program for single or female partner women in Catalonia. EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE. 2021; 26(4). DOI:10.1080/13625187.2021.1891410. PMID:33724129. IF:1,752.
Perello J, Tarruella JR, Calaf J. Heavy menstrual bleeding and its detection in clinical practice. MEDICINA CLINICA. 2021; 157(7). DOI:10.1016/j.medcli.2021.02.006. PMID:33840528. IF:3,200.

ASSOCIATED GROUPS

Reproductive Health

Main lines of research

Challenges

Group coordination

Members

Publications 2023

Publications 2022

Publications 2021

Main lines of research

Challenges

Group coordination

Members

Publications 2023

Publications 2022

Publications 2021

Institut de Recerca de l’Hospital de la Santa Creu i Sant Pau