Sant Pau - Institut de Recerca

Main lines of research

Involvement of brain areas and release of substances in acute and chronic neuropathic pain.
Sleep disturbance on initiating systemic opioid treatment in patients with severe chronic pain and altered sleep patterns.
Influence of herniated lumbar disc anatomy on the effectiveness of epidural corticosteroids by the interlaminal, paramedial, transforaminal and caudal routes.
Profile in terms of demographics, comorbidities, kind of pain, physical and mental status and disability of patients.

Challenges

Establish the possible differences in brain area involvement between acute and chronic pain.
Establish the different brain substances expressed in patients affected by acute and chronic neuropathic pain.
Determine the extent of chronic pain according to the involvement of different brain areas.
Determine whether the intensity of chronic neuropathic pain assessed by the patient is correlated with the patient’s psychopathology, essentially anxiety, depression and catastrophizing.
Determine the profile of patients who would benefit from treatment with major systemic opioids in relation to night rest and establish the recommendable opioid.

Group coordination

GENOVÉ CORTADA, MARIA MERCÈ FGS
mgenove@santpau.cat

Members

Diaz Jover, Ruben FGS
Ferrandiz Mach, Marta FGS
Heredia Carques, Cristina FGS
Melo Cruz, Martha Cristina FGS
Muñoz Hernandez, Isabel FGS
Piñeiro Rebolo, Maria Angeles FGS
Revuelta Rizo, Miren Eli FGS
Roses Alvarez, Laia FGS
Santeularia Verges, Maria Teresa FGS
Sarmiento Luque, Teresa Eugenia FGS

Publications 2023

(JIF 2023)

-Labandeyra H, Heredia C, Campoy JC, Váldes LF, Prats A, Sala X. Clavipectoral fascia plane block spread: an anatomical study. REGIONAL ANESTHESIA AND PAIN MEDICINE. 2023; :rapm-2023-104785. DOI:10.1136/rapm-2023-104785. PMID:37699731. IF:5,100 (Q1/1D). Document type: Article.

-Popova E, Paniagua P, Álvarez J, Vives M, González A, García Á, Rivas M, Hermenegildo G, Diaz R, Azparren G, Barceló M, Moustafa A-H, Aguilar R, Ordonez J, Alonso P. The Relevance of Implementing the Systematic Screening of Perioperative Myocardial Injury in Noncardiac Surgery Patients. Journal of Clinical Medicine. 2023; 12(16):5371. DOI:10.3390/jcm12165371. PMID:37629413. IF:3,000 (Q1/2D). Document type: Article.

Publications 2022

(JIF 2022)

Devereaux PJ, Marcucci M, Painter TW, Conen D, Lomivorotov V, Sessler DI, Chan MTV, Borges FK, Martínez-Zapata MJ, Wang CY, Xavier D, Ofori SN, Wang MK, Efremov S, Landoni G, Kleinlugtenbelt YV, Szczeklik W, Schmartz D, Garg AX, Short TG, Wittmann M, Meyhoff CS, Amir M, Torres D, Patel A, Duceppe E, Ruetzler K, Parlow JL, Tandon V, Fleischmann E, Polanczyk CA, Lamy A, et al. [Paniagua P], POISE-3 INVESTIGATORS [Díaz-Jover R]. Tranexamic Acid in Patients Undergoing Noncardiac Surgery. NEW ENGLAND JOURNAL OF MEDICINE. 2022; 386(21). DOI:10.1056/NEJMoa2201171. PMID:35363452. IF:158,5 (Q1/1D). Document type: Article.
Heredia C, Díaz-Jover R, Melo M, Revuelta M. Radiofrecuencia pulsada cervical multinivel mediante catéter epidural estimulable.¿ Qué nos puede aportar este abordaje?. Investigación Clínica & Terapéutica. 2020; 37(1):pp.12-16. Document type: Article.
Labandeyra H, Heredia C, Váldes LF, Sala X. Clavipectoral Fascia Plane Block: Is This Hyperreality?. ANESTHESIA AND ANALGESIA. 2022; 135(4). DOI:10.1213/ANE.0000000000006150. PMID:36108196. IF:5,7 (Q1/2D). Document type: Letter.
Medel J, Serrano A, Batet C, Lorente L, Bella S, Ferrandiz M, Monerris MD, Boada S, Villoria J, Ribera MV, Montes A, Videla S. Advances and Pitfalls of Specialized Pain Care through Public and Private Health Care Providers in Catalonia and the Balearic Islands: A Physician’s Survey. Pain Research & Management. 2022; 2022:4077139. DOI:10.1155/2022/4077139. PMID:35637851. IF:2,9 (Q3/6D). Document type: Article.
Melo MC, Santeularia MT, Rius C, Gich IJ, Català E. Influence of comorbidities on pain intensity in patients with chronic low back pain. MEDICINA CLINICA. 2022; 159(2). DOI:10.1016/j.medcli.2021.09.023. PMID:34879972. IF:3,9 (Q2/4D). Document type: Article.

Publications 2021

Calderon-Mediavilla M, Vila-Badia R, Dolz M, Butjosa A, Barajas A, Del Cacho N, Sánchez B, Pardo M, Baños I, Usall J, Ochoa S; GENIPE Group; PROFEP Group [Santos A, Nuñez C]. Depressive symptoms and their relationship with negative and other psychotic symptoms in early onset psychosis. EUROPEAN CHILD & ADOLESCENT PSYCHIATRY. 2021;30(9):1383-1390. DOI:10.1007/s00787-020-01618-0. PMID: 32865655. IF:5,349.
de La Piscina IM, Najera NP, Rica I, Gaztambide S, Webb SM, Santos A, Moure MD, Fano MP, Hernandez MI, Chueca MJ, Hernandez LC, Soto A, Valdes N, Castano L, Hispanic A. Clinical and genetic characteristics in patients under 30 years with sporadic pituitary adenomas. EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2021; 185(4). DOI:10.1530/EJE-21-0075. PMID:34313605. IF:6,558.
Gil J, Marques M, Jorda M, Fajardo C, Garcia A, Sampedro M, Serra G, Salinas I, Blanco A, Valassi E, Sesmilo G, Carrato C, Camara R, Lamas C, Casano P, Alvarez CV, Bernabeu I, Webb SM, Pico A, Marazuela M, Puig M, Santos A, Vida JI. Molecular determinants of enhanced response to somatostatin receptor ligands after debulking in large GH-producing adenomas. CLINICAL ENDOCRINOLOGY. 2021; 94(5). DOI:10.1111/cen.14339. PMID:32978826. IF:3,523.
Koller T, Ruiz AP, Diaz M, Caro A. Role of fibrinogen concentrates for treatment of critical perioperative hemorrhage. DRUGS OF TODAY. 2021; 57(3). DOI:10.1358/dot.2021.57.3.3250287. PMID:33729219. IF:2,436.
Lee RS, Zandi PP, Santos A, Aulinas A, Carey JL, Webb SM, McCaul ME, Resmini E, Wand GS. Cross-species Association Between Telomere Length and Glucocorticoid Exposure. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2021; 106(12). DOI:10.1210/clinem/dgab519. PMID:34265046. IF:6,134.
Santos A, Webb SM, Resmini E. Psychological complications of Cushing’s syndrome. Current Opinion in Endocrinology Diabetes and Obesity. 2021; 28(3). DOI:10.1097/MED.0000000000000633. PMID:33764929. IF:3,626.
Webb SM, Kristensen J, Vitali D, van S, van C, Santos A, Nordenstrom A. EndoERN patient survey on their perception of health care experience and of unmet needs for rare endocrine diseases. ENDOCRINE. 2021; 71(3). DOI:10.1007/s12020-021-02625-0. PMID:33544353. IF:3,925.

Introduction

Main lines of research

Involvement of brain areas and release of substances in acute and chronic neuropathic pain.
Sleep disturbance on initiating systemic opioid treatment in patients with severe chronic pain and altered sleep patterns.
Influence of herniated lumbar disc anatomy on the effectiveness of epidural corticosteroids by the interlaminal, paramedial, transforaminal and caudal routes.
Profile in terms of demographics, comorbidities, kind of pain, physical and mental status and disability of patients.

Challenges

Establish the possible differences in brain area involvement between acute and chronic pain.
Establish the different brain substances expressed in patients affected by acute and chronic neuropathic pain.
Determine the extent of chronic pain according to the involvement of different brain areas.
Determine whether the intensity of chronic neuropathic pain assessed by the patient is correlated with the patient’s psychopathology, essentially anxiety, depression and catastrophizing.
Determine the profile of patients who would benefit from treatment with major systemic opioids in relation to night rest and establish the recommendable opioid.

Team

Group coordination

GENOVÉ CORTADA, MARIA MERCÈ FGS
mgenove@santpau.cat

Members

Scientific output

Publications 2023

(JIF 2023)

Publications 2022

(JIF 2022)

Devereaux PJ, Marcucci M, Painter TW, Conen D, Lomivorotov V, Sessler DI, Chan MTV, Borges FK, Martínez-Zapata MJ, Wang CY, Xavier D, Ofori SN, Wang MK, Efremov S, Landoni G, Kleinlugtenbelt YV, Szczeklik W, Schmartz D, Garg AX, Short TG, Wittmann M, Meyhoff CS, Amir M, Torres D, Patel A, Duceppe E, Ruetzler K, Parlow JL, Tandon V, Fleischmann E, Polanczyk CA, Lamy A, et al. [Paniagua P], POISE-3 INVESTIGATORS [Díaz-Jover R]. Tranexamic Acid in Patients Undergoing Noncardiac Surgery. NEW ENGLAND JOURNAL OF MEDICINE. 2022; 386(21). DOI:10.1056/NEJMoa2201171. PMID:35363452. IF:158,5 (Q1/1D). Document type: Article.
Heredia C, Díaz-Jover R, Melo M, Revuelta M. Radiofrecuencia pulsada cervical multinivel mediante catéter epidural estimulable.¿ Qué nos puede aportar este abordaje?. Investigación Clínica & Terapéutica. 2020; 37(1):pp.12-16. Document type: Article.
Labandeyra H, Heredia C, Váldes LF, Sala X. Clavipectoral Fascia Plane Block: Is This Hyperreality?. ANESTHESIA AND ANALGESIA. 2022; 135(4). DOI:10.1213/ANE.0000000000006150. PMID:36108196. IF:5,7 (Q1/2D). Document type: Letter.
Medel J, Serrano A, Batet C, Lorente L, Bella S, Ferrandiz M, Monerris MD, Boada S, Villoria J, Ribera MV, Montes A, Videla S. Advances and Pitfalls of Specialized Pain Care through Public and Private Health Care Providers in Catalonia and the Balearic Islands: A Physician’s Survey. Pain Research & Management. 2022; 2022:4077139. DOI:10.1155/2022/4077139. PMID:35637851. IF:2,9 (Q3/6D). Document type: Article.
Melo MC, Santeularia MT, Rius C, Gich IJ, Català E. Influence of comorbidities on pain intensity in patients with chronic low back pain. MEDICINA CLINICA. 2022; 159(2). DOI:10.1016/j.medcli.2021.09.023. PMID:34879972. IF:3,9 (Q2/4D). Document type: Article.

Publications 2021

Calderon-Mediavilla M, Vila-Badia R, Dolz M, Butjosa A, Barajas A, Del Cacho N, Sánchez B, Pardo M, Baños I, Usall J, Ochoa S; GENIPE Group; PROFEP Group [Santos A, Nuñez C]. Depressive symptoms and their relationship with negative and other psychotic symptoms in early onset psychosis. EUROPEAN CHILD & ADOLESCENT PSYCHIATRY. 2021;30(9):1383-1390. DOI:10.1007/s00787-020-01618-0. PMID: 32865655. IF:5,349.
de La Piscina IM, Najera NP, Rica I, Gaztambide S, Webb SM, Santos A, Moure MD, Fano MP, Hernandez MI, Chueca MJ, Hernandez LC, Soto A, Valdes N, Castano L, Hispanic A. Clinical and genetic characteristics in patients under 30 years with sporadic pituitary adenomas. EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2021; 185(4). DOI:10.1530/EJE-21-0075. PMID:34313605. IF:6,558.
Gil J, Marques M, Jorda M, Fajardo C, Garcia A, Sampedro M, Serra G, Salinas I, Blanco A, Valassi E, Sesmilo G, Carrato C, Camara R, Lamas C, Casano P, Alvarez CV, Bernabeu I, Webb SM, Pico A, Marazuela M, Puig M, Santos A, Vida JI. Molecular determinants of enhanced response to somatostatin receptor ligands after debulking in large GH-producing adenomas. CLINICAL ENDOCRINOLOGY. 2021; 94(5). DOI:10.1111/cen.14339. PMID:32978826. IF:3,523.
Koller T, Ruiz AP, Diaz M, Caro A. Role of fibrinogen concentrates for treatment of critical perioperative hemorrhage. DRUGS OF TODAY. 2021; 57(3). DOI:10.1358/dot.2021.57.3.3250287. PMID:33729219. IF:2,436.
Lee RS, Zandi PP, Santos A, Aulinas A, Carey JL, Webb SM, McCaul ME, Resmini E, Wand GS. Cross-species Association Between Telomere Length and Glucocorticoid Exposure. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2021; 106(12). DOI:10.1210/clinem/dgab519. PMID:34265046. IF:6,134.
Santos A, Webb SM, Resmini E. Psychological complications of Cushing’s syndrome. Current Opinion in Endocrinology Diabetes and Obesity. 2021; 28(3). DOI:10.1097/MED.0000000000000633. PMID:33764929. IF:3,626.
Webb SM, Kristensen J, Vitali D, van S, van C, Santos A, Nordenstrom A. EndoERN patient survey on their perception of health care experience and of unmet needs for rare endocrine diseases. ENDOCRINE. 2021; 71(3). DOI:10.1007/s12020-021-02625-0. PMID:33544353. IF:3,925.

ASSOCIATED GROUPS

Pain and Neurosciences

Main lines of research

Challenges

Group coordination

Members

Publications 2023

Publications 2022

Publications 2021

Main lines of research

Challenges

Group coordination

Members

Publications 2023

Publications 2022

Publications 2021

Institut de Recerca de l’Hospital de la Santa Creu i Sant Pau