Chronic pain is an important clinical problem due to the low efficacy of conventional treatments and their numerous side effects.
Chronic pain is also accompanied by affective disorders such as depression, anxiety and memory deficits, which exert a negative influence on the perception of pain, creating a vicious circle that contributes to the impairment in the quality of life of patients.
At present, the treatment of chronic pain and the linked emotional disorders is a major challenge.
Our main objective is to find new treatments that effectively relieve chronic pain and the associated comorbidities by using pharmacological, molecular and genetic techniques.
Main research lines:
Chronic pain is an important clinical problem due to the low efficacy of conventional treatments and their numerous side effects.
Chronic pain is also accompanied by affective disorders such as depression, anxiety and memory deficits, which exert a negative influence on the perception of pain, creating a vicious circle that contributes to the impairment in the quality of life of patients.
At present, the treatment of chronic pain and the linked emotional disorders is a major challenge.
Our main objective is to find new treatments that effectively relieve chronic pain and the associated comorbidities by using pharmacological, molecular and genetic techniques.
Main research lines:
POL RIGAU, OLGA IR
opol@santpau.cat
Barcena Espla, Alejandra UAB
Kordikowski Boix, Rebecca UAB
Martinez Martel, Ignacio UAB
Negrini Ferrari, Sylmara Esther UAB
(JIF 2022)
-Bai X, Batalle G, Martinez I, OLGA R. Hydrogen Sulfide Interacting with Cannabinoid 2 Receptors during Sciatic Nerve Injury-Induced Neuropathic Pain. Antioxidants. 2023; 12(6):1179. DOI:10.3390/antiox12061179. PMID:37371911. IF:7,000 (Q1/1D). Document type: Article.
-Batallé G, Bai X, Balboni G, OLGA R. The Impact of UFP-512 in Mice with Osteoarthritis Pain: The Role of Hydrogen Sulfide. Antioxidants. 2023; 12(12):2085. DOI:10.3390/antiox12122085. PMID:38136204. IF:7,000 (Q1/1D). Document type: Article.
-Martinez I, OLGA R. A Novel Therapy for Cisplatin-Induced Allodynia and Dysfunctional and Emotional Impairments in Male and Female Mice. Antioxidants. 2023; 12(12):2063. DOI:10.3390/antiox12122063. PMID:38136183. IF:7,000 (Q1/1D). Document type: Article.
-Pérez M, Suárez I, Bai X, Martínez I, Ciaffaglione V, Pittalà V, Salerno L, OLGA R. Novel Heme Oxygenase-1 Inducers Palliate Inflammatory Pain and Emotional Disorders by Regulating NLRP3 Inflammasome and Activating the Antioxidant Pathway. Antioxidants. 2023; 12(10):1794. DOI:10.3390/antiox12101794. PMID:37891874. IF:7,000 (Q1/1D). Document type: Article.
-Suárez I, Pérez M, Bai X, Martínez I, Intagliata S, Pittalà V, Salerno L, OLGA R. The Inhibition of Neuropathic Pain Incited by Nerve Injury and Accompanying Mood Disorders by New Heme Oxygenase-1 Inducers: Mechanisms Implicated. Antioxidants. 2023; 12(10):1859. DOI:10.3390/antiox12101859. PMID:37891937. IF:7,000 (Q1/1D). Document type: Article.
(JIF 2022)