Sant Pau - Institut de Recerca

Main lines of research

Brain neurorepair after stroke.
Role of statins in ischemic and haemorrhagic stroke.
Prevention of cerebral haemorrhage with anticoagulants.
Endothelial progenitor cells in stroke.
Aetiological classification of brain haemorrhage.
Pathophysiology of hematoma growth in acute cerebral haemorrhage.
Benefits and risks of intravenous thrombolysis.
Sonothrombolysis.
Non-invasive monitoring of cerebral flow with applied optic methods.
Participation in clinical trials.

Challenges

Enhance cooperation with other groups in the framework of Spanish stroke research.
Network (RETICS/INVICTUS) and also intrahospital cooperation (the Catalan Institute of Cardiovascular Sciences and the Haemostasis-Thrombosis group) and extra-hospital cooperation (with groups managed by Dr. García-Verdugo in Valencia, Dr. Arús at the Autonomous University of Barcelona, Dr. Anna Planas at Clinic Hospital, Dr. Turgut Durduran at ICFO). To obtain funding from FIS, regional authorities and private companies.
Increase the number of contracted and grant-aided researchers and professionally develop existing researchers.

Group coordination

MARTI FABREGAS, JOAN FGS
jmarti@santpau.cat

Members

Aguilera Simon, Ana IR
Camps Renom, Pol FGS
Ezcurra Diaz, Garbiñe IR
Guasch Jimenez, Marina IR
Lambea Gil, Alvaro IR
Marin Bueno, Rebeca IR
Martinez Domeño, Alejandro FGS
Martinez Gonzalez, Jose Pablo FGS
Prats Sanchez, Luis Antonio FGS
Puig Grifol, Nuria IR
Ramos Pachon, Anna FGS
Yelamos Morales, Africa IR

Publications 2023

(JIF 2022)

-Benitez S, Puig N, Rives J, Sole A, Sanchez JL. Can Electronegative LDL Act as a Multienzymatic Complex?. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023; 24(8):7074. DOI:10.3390/ijms24087074. PMID:37108253. IF:5,600 (Q1/3D). Document type: Review.

-Bonaterra A, Benítez S, Pancorbo O, Rodríguez D, Vert C, Rovira A, Freijo MM, Tur S, Martínez M, Portela PC, Vera R, Lebrato L, Arenillas JF, Pérez S, Domínguez A, Fabregas JM, Mauri G, Montaner J, Sánchez JL, Hernández M. Association of candidate genetic variants and circulating levels of ApoE/ApoJ with common neuroimaging features of cerebral amyloid angiopathy. Frontiers in Aging Neuroscience. 2023; 15:1134399. DOI:10.3389/fnagi.2023.1134399. PMID:37113571. IF:4,800 (Q2/3D). Document type: Article.

-Garcia E, Camps P, Puig N, Fernández A, Aguilera A, Benitez A, Solé A, Vilades D, Sanchez JL, Martí J, Jiménez E, Benitez S, Llorente V. Soluble low-density lipoprotein receptor-related protein 1 as a surrogate marker of carotid plaque inflammation assessed by 18F-FDG PET in patients with a recent ischemic stroke. Journal of Translational Medicine. 2023; 21(1):131. DOI:10.1186/s12967-022-03867-w. PMID:36805772. IF:7,400 (Q1/3D). Document type: Article.

-Gorey S, McCabe JJ, Camps P, Giannotti N, McNulty JP, Barry M, Cassidy T, Cronin S, Dolan E, Fernández A, Foley S, Harbison J, O’Connell M, Williams DJ, Marnane M, Martí J, Kelly PJ. Symptomatic Carotid Atheroma Inflammation Lumen-stenosis score compared with Oxford and Essen risk scores to predict recurrent stroke in symptomatic carotid stenosis. European Stroke Journal. 2023:23969873231186911. DOI:10.1177/23969873231186911. PMID:37480278. IF:6,100 (Q1/2D). Document type: Article.

-Lambea A. Neurology teaching difficulties and the academic consequences of the COVID-19 pandemic. Reply. REVISTA DE NEUROLOGIA. 2023; 77(5). DOI:10.33588/rn.7705.2023189. PMID:37612831. IF:1,200 (Q4/10D). Document type: Letter.

-Lledós M, Prats L, Llucià L, Cárcel J, Muino E, Cullell N, Gallego C, Martín JM, Aguilera A, Guasch M, Guisado D, Ramos A, Martínez A, Izquierdo A, Marín R, Camps P, Martí J, Fernández I. Ischaemic stroke patients present sex differences in gut microbiota. EUROPEAN JOURNAL OF NEUROLOGY. 2023; 30(11). DOI:10.1111/ene.15931. PMID:37329328. IF:5,100 (Q1/3D). Document type: Article.

-Llucià L, Muiño E, Cullell N, Cárcel J, Lledós M, Gallego C, Martin J, Martí J, Aguilera A, Planas AM, DeDiego ML, de Felipe A, Masjuan J, García S, Segura T, González E, Serrano G, Domínguez A, Menéndez P, Montaner J, Migeotte I, Rahmouni S, Darcis G, Bernardo D, Rojo S, Schulte EC, Protzer U, Fricke L, Winter C, Niemi M, Cordioli M, Delgado P, Fernández I. Genetic Architecture of Ischaemic Strokes after COVID-19 Shows Similarities with Large Vessel Strokes. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023; 24(17):13452. DOI:10.3390/ijms241713452. PMID:37686257. IF:5,600 (Q1/3D). Document type: Article.

-Marti J, Camps P, Best JG, Ramos A, Guasch M, Martinez A, Guisado D, Gomez BM, Ambler G, Wilson D, Lee KJ, Lim JS, Bae HJ, Shiozawa M, Koga M, Toyoda K, Hennerici MG, Chabriat H, Jouvent E, Wong DYK, Mak H, Lau KK, Kim YD, Song TJ, Heo JH, Eppinger S, Gattringer T, Uysal E, Demirelli DS, Bornstein N, Ben E, Hallevi H, Molad JA, Nishihara M, Tanaka J, Hara H, Yakushiji Y, Coutts SB, Smith E, Polymeris AA, Wagner B, Seiffge D, Lyrer PA, Peters N, Engelter ST, Salman RA, Jager HR, Lip GYH, Goeldlin M, Panos L, Karayiannis CC, Phan TG, Srikanth VK, Christ N, Gunkel S, Fluri F, Leung TW, Soo Y, Chu WN, Abrigo J, Barbato C, Browning S, Simister R, Mendyk AM, Bordet R, Hilal S, Gyanwali B, Chen CSP, Jung SM, Orken DN, Werring D, Prats L, Microbleeds Int Collaborative N. Stroke Risk and Antithrombotic Treatment During Follow-up of Patients With Ischemic Stroke and Cortical Superficial Siderosis. NEUROLOGY. 2023; 100(12):e1267-e1281. DOI:10.1212/WNL.0000000000201723. PMID:36535778. IF:9,900 (Q1/1D). Document type: Article.

-Martinez A, Xuclà T, Collet R, Olmedo G, Martí J, Izquierdo A, Martínez A, Prats L, Guasch M, Guisado D, Ramos A, Camps P. Clinical characteristics and outcome of amaurosis fugax due to transient retinal ischemia: Results from a contemporary cohort. Journal of Stroke & Cerebrovascular Diseases. 2023; 32(11):107335. DOI:10.1016/j.jstrokecerebrovasdis.2023.107335. PMID:37748428. IF:2,500 (Q3/7D). Document type: Article.

-Meinel TR, Wilson D, Gensicke H, Scheitz JF, Ringleb P, Goganau I, Kaesmacher J, Bae H-J, Kim DY, Kermer P, Suzuki K, Kimura K, Macha K, Koga M, Wada S, Altersberger V, Salerno A, Palanikumar L, Zini A, Forlivesi S, Kellert L, Wischmann J, Kristoffersen ES, Beharry J, Barber PA, Hong JB, Cereda C, Schlemm E, Yakushiji Y, Poli S, Leker R, Romoli M, Zedde M, Curtze S, Ikenberg B, Uphaus T, Giannandrea D, Portela PC, Veltkamp R, Ranta A, Arnold M, Fischer U, Cha J-K, Wu TY, Purrucker JC, Seiffge DJ, Kägi G, Engelter S, Nolte CH, Kallmünzer B, Michel P, Kleinig TJ, Fink J, Rønning OM, Campbell B, Nederkoorn PJ, Thomalla G, Kunieda T, Poli K, Béjot Y, Soo Y, Garcia C, Ntaios G, Cordonnier C, Marto JP, Bigliardi G, Lun F, Choi PMC, Steiner T, Ustrell X, Werring D, Wegener S, Pezzini A, Du H, Martí J, Cánovas D, Strbian D, Padjen V, Yaghi S, Stretz C, Kim J-T. Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants. JAMA Neurology. 2023; 80(3)DOI:10.1001/jamaneurol.2022.4782. PMID:36807495. IF:29,000 (Q1/1D). Document type: Article.

-Munoz SS, Campillo M, Borrega CS, Azeli Y, Gil SQ, Ruiz A, Albacete G, Peral OM, Lluch S, Delgado SA, Blas YS, Urra X, Calderon DC, Fabregas JM, Jacobi MR, Portela PC, Garcia FP, Oller ED, Benitez VH, Flores A, Rubiera M, Palomeras E, Garcia A, Soler RS, Roquet DV, Salvat M, Pachon AR, Herrero NPD, Fabrega XJ. Prehospital care process and hospital outcomes in stroke-code cases: comparison of basic and advance life support ambulance attendance. Emergencias. 2023; 35(3). PMID:37350599. IF:5,500 (Q1/2D). Document type: Article.

-Olive M, de la Ossa NP, Jovin T, Abilleira S, Jimenez X, Cardona P, Chamorro A, Flores A, Silva Y, Purroy F, Marti J, Rodriguez A, Zaragoza J, Krupinski J, Canovas D, Choco MG, Mas N, Palomeras E, Cocho D, Aragones JM, Repullo C, Sanjurjo E, Carrion D, Catena E, Costa X, Almendros MC, Barcelo M, Monedero J, Rybyeva M, Diaz G, Ribo M, Catalan Stroke Code Reperfusion CO. Evolution of quality indicators in acute stroke during the RACECAT Trial: Impact in the general population. International Journal of Stroke. 2023; 18(2):17474930221093523. DOI:10.1177/17474930221093523. PMID:35373657. IF:6,700 (Q1/2D). Document type: Article.

-Puig N, Camps P, Sole A, Aguilera A, Jimenez E, Fernandez A, Camacho M, Guasch M, Marin R, Marti J, Martinez A, Prats L, Casoni F, Perez B, Jimenez F, Sanchez JL, Benitez S. Electronegative LDL Is Associated with Plaque Vulnerability in Patients with Ischemic Stroke and Carotid Atherosclerosis. Antioxidants. 2023; 12(2):438. DOI:10.3390/antiox12020438. PMID:36829998. IF:7,000 (Q1/1D). Document type: Article.

-Puig N, Rives J, Estruch M, Aguilera A, Rotllan N, Camacho M, Colomé N, Canals F, Sánchez JL, Benitez S. Presence of Ceramidase Activity in Electronegative LDL. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023; 24(1):165. DOI:10.3390/ijms24010165. PMID:36613609. IF:5,600 (Q1/3D). Document type: Article.

-Puig N, Solé A, Aguilera A, Griñán R, Rotllan N, Camps P, Benitez S. Novel Therapeutic Approaches to Prevent Atherothrombotic Ischemic Stroke in Patients with Carotid Atherosclerosis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023; 24(18):14325. DOI:10.3390/ijms241814325. PMID:37762627. IF:5,600 (Q1/3D). Document type: Review.

-Ramos A, Rodríguez D, Martí J, Millán M, Bustamante A, Martínez M, Serena J, Terceño M, Vera C, Camps P, Prats L, Rodríguez N, Cardona P, Urra X, Solà S, Del Mar M, Salvat M, Ribó M, Abilleira S, Pérez de la Ossa N, Silva Y, RACECAT I. Effect of Bypassing the Closest Stroke Center in Patients with Intracerebral Hemorrhage: A Secondary Analysis of the RACECAT Randomized Clinical Trial. JAMA Neurology. 2023; 80(10). DOI:10.1001/jamaneurol.2023.2754. PMID:37603325. IF:29,000 (Q1/1D). Document type: Article.

-Saldaña I, Cisneros AI, Lambea Á. Neurophobia among resident physicians in the emergency service. REVISTA DE NEUROLOGIA. 2023; 77(12). DOI:10.33588/rn.7712.2023249. IF:1,200 (Q4/10D). Document type: Article.

-Silva Y, Sanchez L, Terceno M, Dorado L, Valls A, Martinez M, Abilleira S, Rubiera M, Quesada H, Llull L, Rodriguez A, Marti J, Sero L, Purroy F, Payo I, Garcia S, Canovas D, Krupinski J, Mas N, Palomeras E, Cocho D, Font MA, Catena E, Puiggros E, Pedroza C, Marin G, Carrion D, Costa X, Almendros MC, Torres I, Colom C, Velasquez JA, Diaz G, JimTnez X, Subirats T, Deulofeu A, Hidalgo V, Salvat M, de la Ossa NP, Catalan Stroke Code R. Sex and gender differences in acute stroke care: metrics, access to treatment and outcome. A territorial analysis of the Stroke Code System of Catalonia. European Stroke Journal. 2023; 8(2). DOI:10.1177/23969873231156260. PMID:37231687. IF:6,100 (Q1/2D). Document type: Article.

-Soo Y, Zietz A, Yiu B, Mok VCT, Polymeris AA, Seiffge D, Ambler G, Wilson D, Leung TWH, Tsang SF, Chu W, Abrigo J, Cheng C, Lee KJ, Lim JS, Shiozawa M, Koga M, Chabriat H, Hennerici M, Wong YK, Mak H, Collet R, Inamura S, Yoshifuji K, Arsava EM, Horstmann S, Purrucker J, Lam BYK, Wong A, Kim YD, Song TJ, Lemmens R, Eppinger S, Gattringer T, Uysal E, Demirelli DS, Bornstein NM, Ben E, Hallevi H, Molad J, Nishihara M, Tanaka J, Coutts SB, Kappelle LJ, Salman RA, Jager R, Lip GYH, Goeldlin MB, Panos LD, Mas JL, Legrand L, Karayiannis C, Phan T, Bellut M, Chappell F, Makin S, Hayden D, Williams D, van Dam DHK, Nederkoorn PJ, Barbato C, Browning S, Wiegertjes K, Tuladhar AM, Mendyk AM, Kohler S, van R, Zhou Y, Xu C, Hilal S, Gyanwali B, Chen C, Lou M, Staals J, Bordet R, Kandiah N, de Leeuw FE, Simister R, Hendrikse J, Wardlaw J, Kelly P, Fluri F, Srikanth V, Calvet D, Jung S, Kwa V, Smith EE, Hara H, Yakushiji Y, Orken DN, Fazekas F, Thijs V, Heo JH, Veltkamp R, Ay H, Imaizumi T, Lau KK, Jouvent E, Toyoda K, Yoshimura S, Bae HJ, Marti J, Prats L, Lyrer P, Best J, Werring D, Engelter ST, Peters N, Microbleeds Int Collaborative N. Impact of Cerebral Microbleeds in Stroke Patients with Atrial Fibrillation. ANNALS OF NEUROLOGY. 2023; 94(1). DOI:10.1002/ana.26642. PMID:36928609. IF:11,200 (Q1/1D). Document type: Article.

-Terceno M, Silva Y, Bashir S, Chamorro A, de la Ossa NP, Hernandez M, Castano C, Camps P, Wenger D, Cardona P, Molina C, Rodriguez A, Canovas D, Purroy F, Salvat M, Serena J, Catalan Stroke Code Reperfusion CO. First pass effect in posterior circulation occlusions: Analysis from the CICAT registry. International Journal of Stroke. 2023; 18(2):17474930221089772. DOI:10.1177/17474930221089772. PMID:35272563. IF:6,700 (Q1/2D). Document type: Article.

-Toscano C, Martínez JP, Guasch M, Ramos A, Martí J, Blanco N, Coronel MF, Domine MC, Martínez A, Prats L, Marín R, Aguilera A, Lambea A, Ezcurra G, Camps P. Asymptomatic parenchymal haemorrhage following endovascular treatment: Impact on functional outcome in patients with acute ischaemic stroke. EUROPEAN JOURNAL OF NEUROLOGY. 2023; DOI:10.1111/ene.16112. PMID:37909802. IF:5,100 (Q1/3D). Document type: Article.

Publications 2022

(JIF 2022)

Camps-Renom P, McCabe J, Martí-Fàbregas J, Giannotti N, Fernandez A, McNulty JP, Baron JC, Barry M, Coutts SB, Cronin S, Delgado R, Dolan E, Foley S, Guasch M, Guisado D, Harbison JA, Horgan G, Kavanagh EC, Marnane M, Martinez A, McDonnell C, Sharma VK, Williams D, Connell MO, Murphy S, Prats L, Kelly PJ. Association of Plaque Inflammation With Stroke Recurrence in Patients With Unproven Benefit From Carotid Revascularization. NEUROLOGY. 2022; 99(2). DOI:10.1212/WNL.0000000000200525. PMID:35418461. IF:9,9 (Q1/1D). Document type: Article.
Carcel J, Muino E, Gallego C, Cullell N, Lledos M, Llucia L, Sobrino T, Campos F, Castillo J, Freijo M, Arenillas JF, Obach V, Alvarez J, Molina CA, Ribo M, Jimenez J, Roquer J, Munoz L, Lopez E, Millan M, Diaz R, Vives C, Serrano G, Segura T, Ibanez L, Heitsch L, Delgado P, Dhar R, Krupinski J, Delgado R, Prats L, Camps-Renom P, Blay N, Sumoy L, de Cid R, Montaner J, Cruchaga C, Lee JM, Martí-Fàbregas J, Fernández-Cadenas I. A Polygenic Risk Score Based on a Cardioembolic Stroke Multitrait Analysis Improves a Clinical Prediction Model for This Stroke Subtype. Frontiers in Cardiovascular Medicine. 2022; 9:940696. DOI:10.3389/fcvm.2022.940696. PMID:35872910. IF:3,6 (Q2/5D). Document type: Article.
Cullell N, Gallego C, Carcel J, Muino E, Llucia L, Lledos M, Martin JM, Molina J, Casas L, Almeria M, Fernández-Cadenas I, Krupinski J. ICA1L Is Associated with Small Vessel Disease: A Proteome-Wide Association Study in Small Vessel Stroke and Intracerebral Haemorrhage. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022; 23(6):3161. DOI:10.3390/ijms23063161. PMID:35328582. IF:5,6 (Q1/3D). Document type: Article.
Cullell N, Soriano C, Gallego C, Carcel J, Torres NP, Muino E, Lledos M, Llucia L, Esteller M, de Moura MC, Montaner J, Fernandez A, Elosua R, Delgado P, Martí-Fàbregas J, Krupinski J, Roquer J, Jimenez J, Fernández-Cadenas I. DNA Methylation and Ischemic Stroke Risk: An Epigenome-Wide Association Study. THROMBOSIS AND HAEMOSTASIS. 2022; 122(10). DOI:10.1055/s-0042-1749328. PMID:35717949. IF:6,7 (Q1/2D). Document type: Article.
Cullell N, Soriano C, Gallego C, Jara M, Muino E, Llucia L, Lledos M, Esteller M, de Moura MC, Montaner J, Rosell A, Delgado P, Martí-Fàbregas J, Krupinski J, Roquer J, Jimenez J, Fernandez I. Altered methylation pattern in EXOC4 is associated with stroke outcome: an epigenome-wide association study. Clinical Epigenetics. 2022; 14(1):124. DOI:10.1186/s13148-022-01340-5. PMID:36180927. IF:5,7 (Q1/2D). Document type: Article.
de la Ossa NP, Abilleira S, Jovin TG, Garcia A, Jimenez X, Urra X, Cardona P, Cocho D, Purroy F, Serena J, Manzanera LS, Vivanco RM, Salvat M, Chamorro A, Gallofre M, Molina CA, Cobo E, Davalos A, Ribo M, Martí J, RACECAT Trial Investigators [Martí-Fàbregas J]. Effect of Direct Transportation to Thrombectomy-Capable Center vs Local Stroke Center on Neurological Outcomes in Patients With Suspected Large-Vessel Occlusion Stroke in Nonurban Areas The RACECAT Randomized Clinical Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 2022; 327(18). DOI:10.1001/jama.2022.4404. PMID:35510397. IF:120,7 (Q1/1D). Document type: Article.
Flores A, Sero L, Gomez M, Ustrell X, Pellise A, Vinas J, Rodriguez P, Monterde A, Castilho G, Rubiera M, Amaro S, Padros M, Cardona P, Martí-Fàbregas J, Molina CA, Serena J, Jimenez FX, Purroy F, Zaragoza J, Cocho D, Palomeras E, Kuprinski J, Mas N, Hernandez M, Sanjurjo E, Carrion D, Costa X, Barcelo M, Monedero J, Catena E, Rybyeba M, Diaz G, de la Ossa NP, Ribo M. The Role of Vascular Imaging atReferral Centers in the Drip and Ship Paradigm. Journal of Stroke & Cerebrovascular Diseases. 2022; 31(1):106209. DOI:10.1016/j.jstrokecerebrovasdis.2021.106209. PMID:34794029. IF:2,5 (Q3/7D). Document type: Article.
Gallego C, Muino E, Carcel J, Llucia L, Lledos M, Martin JM, Cullell N, Fernández-Cadenas I. Genome-Wide Studies in Ischaemic Stroke: Are Genetics Only Useful for Finding Genes?. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022; 23(12):6840. DOI:10.3390/ijms23126840. PMID:35743317. IF:5,6 (Q1/3D). Document type: Review.
Gallego C, Muino E, Cullell N, Carcel J, Lazcano U, Soriano C, Lledos M, Llucia L, Aguilera A, Marin R, Prats L, Camps-Renom P, Delgado R, Martin JM, Delgado P, Martí-Fàbregas J, Montaner J, Krupinski J, Jimenez J, Roquer J, Fernández-Cadenas I. Biological Age Acceleration Is Lower in Women With Ischemic Stroke Compared to Men. STROKE. 2022; 53(7). DOI:10.1161/STROKEAHA.121.037419. PMID:35209739. IF:8,3 (Q1/1D). Document type: Article.
Guisado D, Camps-Renom P, Delgado R, Granell E, Prats L, Martinez A, Guasch M, Acosta MV, Ramos A, Martí-Fàbregas J. Automated scoring of collaterals, blood pressure, and clinical outcome after endovascular treatment in patients with acute ischemic stroke and large-vessel occlusion. Frontiers in Neurology. 2022; 13:944779. DOI:10.3389/fneur.2022.944779. PMID:36016546. IF:3,4 (Q2/5D). Document type: Article.
Ibanez L, Heitsch L, Carrera C, Farias FHG, Del Aguila JL, Dhar R, Budde J, Bergmann K, Bradley J, Harari O, Phuah CL, Lemmens R, Souza A, Moniche F, Cabezas A, Arenillas JF, Krupinksi J, Cullell N, Torres N, Muino E, Carcel J, Martí-Fàbregas J, Delgado R, Marin R, Hornick A, Vives C, Navarro RD, Tur S, Jimenez C, Obach V, Segura T, Serrano G, Chung JW, Roquer J, et al. Multi-ancestry GWAS reveals excitotoxicity associated with outcome after ischaemic stroke. 2022; 145(7). DOI:10.1093/brain/awac080. PMID:35213696. IF:14,5 (Q1/1D). Document type: Article.
Martí-Fàbregas J, Prats-Sánchez L, Ramos-Pachón A. Manejo médico de la hemorragia intracerebral. In: Trillo S, Llull L (Eds.). Manual de neurologia crítica para neurólogos. Ediciones SEN. ISBN: 978-84-124320-5-3. Document type: Book chapter.
Martínez JP, Guerrero R, Medina V, Branera J, Camps-Renom P. Dual-Stentriever technique for retrieval of an unusual middle cerebral artery embolus. 2022; 37(5). DOI:10.1016/j.nrl.2021.08.006. PMID:34509320. IF:3,9 (Q2/4D). Document type: Letter.
Medrano S, Capellades J, Jimenez J, Gonzalez S, Vilas M, Rodriguez A, Ois A, Cuadrado E, Avellaneda C, Fernández-Cadenas I, Merino E, Roquer J, Martí-Fàbregas J, Giralt E. Risk factors analysis according to regional distribution of white matter hyperintensities in a stroke cohort. EUROPEAN RADIOLOGY. 2022; 32(1). DOI:10.1007/s00330-021-08106-2. PMID:34117555. IF:5,9 (Q1/2D). Document type: Article.
Millán M, Ramos A, Dorado L, Bustamante A, Hernández M, Rodríguez L, Gomis M, Remollo S, Castaño C, Werner M, Wenger D, Rubio S, Domínguez M, Terceño M, Paipa AJ, Rodríguez A, Boned S, Camps-Renom P, Cánovas D, Giralt E, López E, Dávalos A, Ros J, Pérez de la Ossa N. Predictors of Functional Outcome After Thrombectomy in Patients With Prestroke Disability in Clinical Practice. 2022; 53(3). DOI:10.1161/STROKEAHA.121.034960. PMID:34702065. IF:8,3 (Q1/1D). Document type: Article.
Mishra A, Malik R, Hachiya T, Jurgenson T, Namba S, Posner DC, Kamanu FK, Koido M, Shi MY, He YY, Georgakis MK, Caro I, Krebs K, Liaw YC, Vaura FC, Lin K, Winsvold BS, Srinivasasainagendra V, Parodi L, Bae HJ, Chauhan G, Chong MCR, Tomppo L, Akinyemi R, Roshchupkin GV, Habib N, Jee YH, Thomassen JQ, Abedi V, Cárcel-Márquez J, Nygaard M, Leonard HL, et al. [Cullell N, Muiño E, Gallego-Fàbrega C, Lledós M, Delgado-Mederos R, Prats-Sánchez L, Camps-Renom P, Martí-Fàbregas J, Fernández-Cadenas I]. Stroke genetics informs drug discovery and risk prediction across ancestries. NATURE. 2022; 611(7934). DOI:10.1038/s41586-022-05165-3. PMID:36180795. IF:64,8 (Q1/1D). Document type: Article.
Pairo E, Rawlik K, Russell CD, Malinauskas T, Wu Y, Millar J, Shen X, Elliott KS, Griffiths F, Oosthuyzen W, Morrice K, Keating S, Wang B, Klaric L, Zechner M, Parkinson N, Siddiq A, Goddard P, Donovan S, Maslove D, Nichol A, Semple MG, Zainy T, Maleady F, Todd L, Salehi S, Knight J, Elgar G, Patch C, Bentley D, Kingsley C, Justice A, Oetjens M, Rader DJ, Fowler TA, et al. [Fernández-Cadenas I, Llucia-Carol M, Cullell N, Muiño E, Cárcel-Márquez J, Martí-Fàbregas J, Jiménez-Xarrié E], GenOMICC C, COVID I, 23andMe I. Whole-genome sequencing reveals host factors underlying critical COVID-19. NATURE. 2022; 607(7917). DOI:10.1038/s41586-022-04576-6. PMID:35255492. IF:64,8 (Q1/1D). Document type: Article.
Pathak GA, Polimanti R, Karjalainen J, Daly M, Ganna A, Daly MJ, Stevens C, Kanai M, Liao RG, Trankiem A, Balaconis MK, Nguyen H, Solomonson M, Veerapen K, Ripatti S, Nkambul L, Bryant S, Sankaran VG, Neale BM, Karczewski KJ, Martin AR, Atkinson EG, Tsuo K, Baya N, Turley P, Gupta R, Walters RK, Palmer DS, Sarma G, Cheng N, Lu W, Churchhouse C, Goldstein JI, King D, et al. [Fernández-Cadenas I, Llucia-Carol M, Cullell N, Muiño E, Cárcel-Márquez J, Martí-Fàbregas J, Jiménez-Xarrié E], COVID-19 Host Genetics Initiative. A first update on mapping the human genetic architecture of COVID-19. NATURE. 2022; 608(7921). DOI:10.1038/s41586-022-04826-7. PMID:35922517. IF:64,8 (Q1/1D). Document type: Editorial material.
Perera KS, Boasquevisque DD, Rao P, Taylor A, Cheng A, Hankey GJ, Lee S, Fabregas JM, Ameriso SF, Field TS, Arauz A, Coutts SB, Arnold M, Mikulik R, Toni D, Mandzia J, Veltkamp RC, Meseguer E, Haeusler KG, Hart RG, Young I. Evaluating Rates of Recurrent Ischemic Stroke Among Young Adults With Embolic Stroke of Undetermined Source The Young ESUS Longitudinal Cohort Study. JAMA Neurology. 2022; 79(5). DOI:10.1001/jamaneurol.2022.0048. PMID:35285869. IF:29 (Q1/1D). Document type: Article.
Prats L, Iruzubieta P, Vesperinas A, Collet R, Martínez A, Guisado D, Camps-Renom P, Delgado R, Guasch M, Ramos A, Rodríguez J, Campo D, Equiza J, de la Riva P, Martínez M, de Arce A, Martí-Fàbregas J. Frequency, Predictors, Etiology, and Outcomes for Deep Intracerebral Hemorrhage without Hypertension. Journal of Stroke & Cerebrovascular Diseases. 2022; 31(3):106293. DOI:10.1016/j.jstrokecerebrovasdis.2021.106293. PMID:35016096. IF:2,5 (Q3/7D). Document type: Article.
Puig N, Camps-Renom P, Camacho M, Aguilera A, Jimenez F, Fernandez A, Marin R, Martí-Fàbregas J, Sanchez JL, Jimenez E, Benitez S. Plasma sICAM-1 as a Biomarker of Carotid Plaque Inflammation in Patients with a Recent Ischemic Stroke. Translational Stroke Research. 2022; 13(5). DOI:10.1007/s12975-022-01002-x. PMID:35237947. IF:6,9 (Q1/1D). Document type: Article.
Renu A, Millan M, San Roman L, Blasco J, Martí-Fàbregas J, Terceno M, Amaro S, Serena J, Urra X, Laredo C, Barranco R, Camps-Renom P, Zarco F, Oleaga L, Cardona P, Castano C, Macho J, Cuadrado E, Vivas E, Lopez A, Guimaraens L, Ramos A, Roquer J, Muchada M, Tomasello A, Davalos A, Torres F, Chamorro A. Effect of Intra-arterial Alteplase vs Placebo Following Successful Thrombectomy on Functional Outcomes in Patients With Large Vessel Occlusion Acute Ischemic Stroke The CHOICE Randomized Clinical Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 2022; 327(9). DOI:10.1001/jama.2022.1645. PMID:35143603. IF:120,7 (Q1/1D). Document type: Article.
Ruiz I, Guisado D, Bulnes V, Green BT. Isolated dilated pupil. BMJ-British Medical Journal. 2022; 376:e069133. DOI:10.1136/bmj-2021-069133. PMID:35361677. IF:105,7 (Q1/1D). Document type: Editorial material.
Sharma M, Smith EE, Pearce LA, Shoamanesh A, Perera KS, Coutts SB, Damgaard D, Ameriso SF, Rha JH, Modrau B, Yoon BW, Romano M, Messe SR, Barlinn J, Lambeck J, Saad F, Berkowitz SD, Mundl H, Connolly SJ, Hart RG, Martí-Fàbregas J, O’Donnell MJ. Frequency and patterns of Brain Infarction in Patients With Embolic Stroke of Undetermined Source: NAVIGATE ESUS Trial. STROKE. 2022; 53(1). DOI:10.1161/STROKEAHA.120.032976. PMID:34538089. IF:8,3 (Q1/1D). Document type: Article.
Sol J, Colas L, Mauri G, Molina J, Galo JD, Torres C, Aymerich N, Ois A, Roquer J, Tur S, Garcia MD, Martí-Fàbregas J, Cruz A, Segura T, Pamplona R, Portero M, Arque G, Jove M, Purroy F. Ischemia preconditioning induces an adaptive response that defines a circulating metabolomic signature in ischemic stroke patients. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2022; 42(12). DOI:10.1177/0271678X221116288. PMID:35869638. IF:6,3 (Q1/2D). Document type: Article.

Publications 2021

Arranz MJ, Gallego C, Martin A, Soler J, Elices M, Dominguez E, Salazar J, Vega D, Briones L, Pascual JC. A genome-wide methylation study reveals X chromosome and childhood trauma methylation alterations associated with borderline personality disorder. Translational Psychiatry. 2021; 11(1):5. DOI:10.1038/s41398-020-01139-z. PMID:33414392. IF:7,989.
Best JG, Ambler G, Wilson D, Lee KJ, Lim JS, Shiozawa M, Koga M, Li LX, Lovelock C, Chabriat H, Hennerici M, Wong YK, Mak HKF, Prats L, Martinez A, Inamura S, Yoshifuji K, Arsava EM, Horstmann S, Purrucker J, Lam BYK, Wong A, Kim YD, Song TJ, Lemmens R, Eppinger S, Gattringer T, Uysal E, Tanriverdi Z, Bornstein NM, Ben E, Hallevi H, et al. [Gomez B, Marti J]. Development of imaging-based risk scores for prediction of intracranial haemorrhage and ischaemic stroke in patients taking antithrombotic therapy after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies. LANCET NEUROLOGY. 2021; 20(4). PMID:33743239. IF:59,935.
Bonaterra A, Fernandez S, Rivas A, Puig N, Benitez S, Pancorbo O, Rodriguez D, Pujadas F, Freijo MD, Tur S, Martinez M, Portela PC, Vera R, Lebrato L, Arenillas JF, Perez S, Montaner J, Sanchez JL, Hernandez M. Comparison of Plasma Lipoprotein Composition and Function in Cerebral Amyloid Angiopathy and Alzheimer’s Disease. Biomedicines. 2021; 9(1):72. DOI:10.3390/biomedicines9010072. PMID:33445800. IF: 4,757
Camps P, Jimenez E, Soler M, Puig N, Aguilera A, Marin R, Prats L, Delgado R, Martinez A, Guisado D, Guasch M, Marti J. Endothelial Progenitor Cells Count after Acute Ischemic Stroke Predicts Functional Outcome in Patients with Carotid Atherosclerosis. Journal of Stroke & Cerebrovascular Diseases. 2021; 30(12): 106144. DOI:10.1016/j.jstrokecerebrovasdis.2021.106144. PMID:34649037. IF: 2,677
Canyelles M, Garcia A, Junza A, Yanes O, Puig N, Ordonez J, Sionis A, Sans J, Alquezar A, Santos D, Rotllan N, Julve J, Tondo M, Escola JC, Blanco F. The Capacity of APOB-Depleted Plasma in Inducing ATP-Binding Cassette A1/G1-Mediated Macrophage Cholesterol Efflux-But Not Gut Microbial-Derived Metabolites-Is Independently Associated with Mortality in Patients with ST-Segment Elevation Myocardial Infarction. Biomedicines. 2021; 9(10):1336. DOI:10.3390/biomedicines9101336. PMID:34680453. IF: 4,757
Carcel J, Cullell N, Muino E, Gallego C, Lledos M, Ibanez L, Krupinski J, Montaner J, Cruchaga C, Lee JM, Gill D, Pare G, Mola M, Roquer J, Jimenez J, Marti J, Fernandez I. Causal Effect of MMP-1 (Matrix Metalloproteinase-1), MMP-8, and MMP-12 Levels on Ischemic Stroke A Mendelian Randomization Study. STROKE. 2021; 52(7). DOI:10.1161/STROKEAHA.120.033041. PMID:33902302. IF: 10,170
Carrera C, Carcel J, Cullell N, Torres N, Muino E, Castillo J, Sobrino T, Campos F, Rodriguez E, Llucia L, Millan M, Munoz L, Lopez E, Bustamante A, Ribo M, Alvarez J, Jimenez J, Roquer J, Giralt E, Soriano C, Mola M, Vives C, Navarro RD, Tur S, Obach V, Arenillas JF, Segura T, Serrano G, Marti J, Delgado R, Freijo MM, Moniche F, et al. [Gallego C, Fernandez I]. Single nucleotide variations in ZBTB46 are associated with post-thrombolytic parenchymal haematoma. BRAIN. 2021; 144. DOI:10.1093/brain/awab090. PMID:33723576. IF: 15,255
Cole JW, Adigun T, Akinyemi R, Akpa OM, Bell S, Chen BW, Conde JJ, Dobao UL, Fernandez I, Fornage M, Gallego C, Jern C, Krawczak M, Lindgren A, Markus HS, Melander O, Owolabi M, Schlicht K, Soderholm M, Srinivasasainagendra V, Tarraga CS, Stenman M, Tiwari H, Corasaniti M, Fecteau N, Guizzardi B, Lopez H, Nguyen K, Gaynor B, O’Connor T, et al. The copy number variation and stroke (CaNVAS) risk and outcome study. PLoS One. 2021; 16(4):e0248791. DOI:10.1371/journal.pone.0248791. PMID:33872305. IF: 3,752
Cullell N, Carcel J, Gallego C, Muino E, Llucia L, Lledos M, Amaut K, Krupinski J, Fernandez I. Sleep/wake cycle alterations as a cause of neurodegenerative diseases: a mendelian randomization study. NEUROBIOLOGY OF AGING. 2021; 106. DOI:10.1016/j.neurobiolaging.2021.05.008. PMID:34130902. IF: 5,133
Genua I, Puig N, Minambres I, Benitez S, Gil P, Grau M, Rivas A, Balague C, Fernandez S, Garcia A, Perez A, Sanchez JL. Changes in the Composition and Function of Lipoproteins after Bariatric Surgery in Patients with Severe Obesity. Journal of Clinical Medicine. 2021; 10(8):1716. DOI:10.3390/jcm10081716. PMID:33923393. IF: 4,964
Gomez A, Lazcano U, Vivanco RM, Prats L, Guisado D, Delgado R, Camps P, Domeno AM, Cuadrado E, Steinhauer EG, Jimenez J, Soriano C, Avellaneda C, Rodriguez A, Marti J, Ois A, Roquer J. Defining Minor Intracerebral Hemorrhage. CEREBROVASCULAR DISEASES. 2021; 50(4). DOI:10.1159/000515169. PMID:33831860. IF: 3,104
Gregori C, Mesquita RC, Favilla CG, Busch DR, Blanco I, Zirak P, Frisk LK, Avtzi S, Maruccia F, Giacalone G, Cotta G, Camps P, Mullen MT, Marti J, Prats L, Martinez A, Kasner SE, Greenberg JH, Zhou C, Edlow BL, Putt ME, Detre JA, Yodh AG, Durduran T, Delgado R. Blood flow response to orthostatic challenge identifies signatures of the failure of static cerebral autoregulation in patients with cerebrovascular disease. BMC Neurology. 2021; 21(1):154. DOI:10.1186/s12883-021-02179-8. PMID:33836684. IF: 2,903
Guasch M, Prats L, Martinez A, Delgado R, Camps P, Guisado D, Abilleira S, Marti J. Patterns of Admission and Outcomes for Patients with Intracranial Hemorrhage in Catalonia, Spain. World Neurosurgery. 2021; 149. DOI:10.1016/j.wneu.2020.12.129. PMID:33412328. IF: 2,210
Guisado-Alonso D, Edo MC, Estrada Alarcón PV, García-Sánchez SM, Font MÀ, Mena Romo L, Marrero-González P, Mengual JJ, Castrillo L, Montull C, Corominas H, Gómez-Choco M. Progression of Large Vessel Disease in Patients With Giant Cell Arteritis-Associated Ischemic Stroke: The Role of Vascular Imaging: A Case Series. JCR-JOURNAL OF CLINICAL RHEUMATOLOGY. 2021;27(8):e418-e424. DOI:10.1097/RHU.0000000000001498. PMID: 32732523. IF: 3,902
Guisado D, Martinez A, Prats L, Delgado R, Camps P, Abilleira S, De la Ossa NP, Ramos A, Cardona P, Rodriguez A, Molina CA, Rudilosso S, Marti J. Reasons for Not Performing Mechanical Thrombectomy A Population-Based Study of Stroke Codes. STROKE. 2021; 52(9). DOI:10.1161/STROKEAHA.120.032648. PMID:34289711. IF: 10,170
Heitsch L, Ibanez L, Carrera C, Binkley MM, Strbian D, Tatlisumak T, Bustamante A, Ribo M, Molina C, Davalos A, Lopez E, Munoz L, Soriano C, Giralt E, Obach V, Slowik A, Pera J, Lapicka K, Derbisz J, Sobrino T, Castillo J, Campos F, Rodriguez E, Arias S, Segura T, Serrano G, Vives C, Diaz R, Tur S, Jimenez C, Marti J, Delgado R, et al. [Cullell N, Muino E, Carcel J, Fernandez I]. Early Neurological Change After Ischemic Stroke Is Associated With 90-Day Outcome. STROKE. 2021; 52(1). DOI:10.1161/STROKEAHA.119.028687. PMID:33317415. IF: 10,170
Kim NY, Hsu J, Talmasov D, Joutsa J, Soussand L, Wu O, Rost NS, Morenas E, Marti J, Pascual A, Corlett PR, Fox MD. Lesions causing hallucinations localize to one common brain network. MOLECULAR PSYCHIATRY. 2021; 26(4). DOI:10.1038/s41380-019-0565-3. PMID:31659272. IF: 13,437
Llucia L, Muino E, Gallego C, Carcel J, Martin J, Lledos M, Cullell N, Fernandez I. Pharmacogenetics studies in stroke patients treated with rtPA: a review of the most interesting findings. PHARMACOGENOMICS. 2021; 22(16). DOI:10.2217/pgs-2021-0100. PMID:34698533. IF: 2,638
Marti J, Guisado D, Delgado R, Martinez A, Prats L, Guasch M, Cardona P, Nunez A, Requena M, Rubiera M, Olive M, Bustamante A, Gomis M, Amaro S, Llull L, Ustrell X, de Oliveira GC, Sero L, Gomez M, Mena L, Serena J, Viturro SB, Purroy F, Vicente M, Rodriguez A, Ois A, Catena E, Garcia MC, Barrachina O, Palomeras E, Krupinski J, et al. [Camps P]. Impact of COVID-19 Infection on the Outcome of Patients With Ischemic Stroke. STROKE. 2021; 52(12). DOI:10.1161/STROKEAHA.121.034883. PMID:34455823. IF: 10,170
Martin L, Camps P, Lleixa C, Pascual E, Diaz J, Rojas R, De Luna N, Gallardo E, Cortes E, Munoz L, Alcolea D, Lleo A, Casasnovas C, Homedes C, Gutierrez G, Jimeno MC, Berciano J, Sedano MJ, Garcia T, Pardo J, Marquez C, Rojas I, Jerico I, Martinez E, de la Tassa GM, Dominguez C, Illa I, Querol L. Serum neurofilament light chain predicts long-term prognosis in Guillain-Barre syndrome patients. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. 2021; 92(1). DOI:10.1136/jnnp-2020-323899. PMID:33154183. IF: 13,654
McCabe JJ, Camps P, Giannotti N, McNulty JP, Coveney S, Murphy S, Barry M, Harbison J, Cronin S, Williams D, Horgan G, Dolan E, Cassidy T, McDonnell C, Kavanagh E, Foley S, Collins S, O’Connell M, Fernandez A, Delgado R, Marnane M, Marti J, Kelly PJ. Carotid Plaque Inflammation Imaged by PET and Prediction of Recurrent Stroke at 5 Years. NEUROLOGY. 2021; 97(23). DOI:10.1212/WNL.0000000000012909. PMID:34610991. IF: 11,800
Millán M, Ramos A, Dorado L, Bustamante A, Hernández M, Rodríguez L, Gomis M, Remollo S, Castaño C, Werner M, Wenger D, Rubio S, Domínguez M, Terceño M, Paipa AJ, Rodríguez A, Boned S, Camps P, Cánovas D, Giralt E, López E, Dávalos A, Ros J, Pérez de la Ossa N. Predictors of Functional Outcome After Thrombectomy in Patients With Prestroke Disability in Clinical Practice. STROKE. 2022; 53(3). DOI:10.1161/STROKEAHA.121.034960. PMID:34702065. IF: 10,170
Muino E, Carcel J, Carrera C, Llucia L, Gallego C, Cullell N, Lledos M, Castillo J, Sobrino T, Campos F, Rodriguez E, Millan M, Munoz L, Bustamante A, Lopez E, Ribo M, Alvarez J, Jimenez J, Roquer J, Giralt E, Soriano C, Vives C, Navarro RD, Tur S, Obach V, Arenillas JF, Segura T, Serrano G, Marti J, Delgado R, Camps P, Prats L, Guisado D, et al., Int Stroke Genetic C, Spanish Stroke Genetic C [Guasch M, Marin R, Martinez A, Fernandez I]. RP11-362K2.2:RP11-767I20.1 Genetic Variation Is Associated with Post-Reperfusion Therapy Parenchymal Hematoma. A GWAS Meta-Analysis. Journal of Clinical Medicine. 2021; 10(14):3137. DOI:10.3390/jcm10143137. PMID:34300314. IF: 4,964
Muino E, Maisterra O, Jimenez J, Cullell N, Carrera C, Torres NP, Carcel J, Gallego C, Lledos M, Gonzalez J, Olmos F, Espejo E, March A, Pujol R, Rodriguez A, Romeral G, Krupinski J, Marti J, Montaner J, Roquer J, Fernandez I. Genome-wide transcriptome study in skin biopsies reveals an association of E2F4 with cadasil and cognitive impairment. Scientific Reports. 2021; 11(1):6846. DOI:10.1038/s41598-021-86349-1. PMID:33767277. IF: 4,996
Nogueira RG, Abdalkader M, Qureshi MM, Frankel MR, Mansour OY, Yamagami H, Qiu Z, Farhoudi M, Siegler JE, Yaghi S, Raz E, Sakai N, Ohara N, Piotin M, Mechtouff L, Eker O, Chalumeau V, Kleinig TJ, Pop R, Liu J, Winters HS, Shang X, Vasquez AR, Blasco J, Arenillas JF, Martinez-Galdamez M, Brehm A, Psychogios MN, Lylyk P, et al. [Ramos-Pachón A]. Global impact of COVID-19 on stroke care. International Journal of Stroke. 2021;16(5):573-584. DOI:10.1177/1747493021991652. PMID: 33459583. IF: 6,948
Pérez C, López A, Gómez C, Aguirre C, de Felipe A, de la Riva P, Calleja S, Arjona A, Serrano M, Navarro MP, Delgado R, Bashir S, Llul L, Egido J, García S, Díez N, Benavente L, de la Torre JD, Tejada H, Vesperinas A, Sánchez L, Trillo S. Management of cerebral venous thrombosis in Spain: MOTIVATE descriptive study. NEUROLOGIA. 2021. DOI:10.1016/j.nrl.2021.05.016. IF: 5,486
Ramos-Araque ME, Siegler JE, Ribo M, Requena M, López C, de Lera M, Arenillas JF, Pérez IH, Gómez-Vicente B, Talavera B, Portela PC, Guillen AN, Urra X, Llull L, Renú A, Nguyen TN, Jillella D, Nahab F, Nogueira R, Haussen D, Then R, Thon JM, Esparragoza LR, Hernández-Pérez M, Bustamante A, Mansour OY, Megahed M, Hassan T, Liebeskind DS, et al.; SVIN Multinational Registry and Task Force [Ramos A]. Stroke etiologies in patients with COVID-19: the SVIN COVID-19 multinational registry. BMC Neurology. 2021;21(1):43. DOI:10.1186/s12883-021-02075-1. PMID: 33514335. IF: 2,903
Ramos-Pachón A, López-Cancio E, Bustamante A, Pérez de la Ossa N, Millán M, Hernández-Pérez M, Garcia-Berrocoso T, Cardona P, Rubiera M, Serena J, Ustrell X, Garcés M, Terceño M, Dávalos A, Montaner J. D-Dimer as Predictor of Large Vessel Occlusion in Acute Ischemic Stroke. Stroke. 2021;52(3):852-858. DOI:10.1161/STROKEAHA.120.031657. PMID: 33563016. IF: 10,170
Ramos A, Garcia A, Millan M, Ribo M, Amaro S, Cardona P, Marti J, Roquer J, Silva Y, Ustrell X, Purroy F, Gomez M, Zaragoza J, Canovas D, Krupinski J, Sala NM, Palomeras E, Cocho D, Redondo L, Repullo C, Sanjurjo E, Carrion D, Lopez M, Almendros MC, Barcelo M, Monedero J, Catena E, Rybyeba M, Diaz G, Jimenez X, Sola S, Hidalgo V, Pueyo MJ, de la Ossa NP, Urra X. Bottlenecks in the Acute Stroke Care System during the COVID-19 Pandemic in Catalonia. CEREBROVASCULAR DISEASES. 2021; 50(5). DOI:10.1159/000516309. PMID:34023822. IF: 3,104
Renú A, Blasco J, Millán M, Martí-Fàbregas J, Cardona P, Oleaga L, Macho J, Molina C, Roquer J, Amaro S, Dávalos A, Zarco F, Laredo C, Tomasello A, Guimaraens L, Barranco R, Castaño C, Vivas E, Ramos A, López-Rueda A, Urra X, Muchada M, Cuadrado-Godía E, Camps-Renom P, Román LS, Ríos J, Leira EC, Jovin T, Torres F, Chamorro Á; CHOICE Investigators. The Chemical Optimization of Cerebral Embolectomy trial: Study protocol. International Journal of Stroke. 2021;16(1):110-116. DOI:10.1177/1747493019895656. PMID: 31852410. IF: 6,948
Rudilosso S, Laredo C, Amaro S, Renú A, Llull L, Obach V, Moreno J, Ribó M, Abilleira S, Cardona P, Martí-Fàbregas J, Pérez de la Ossa N, Ramos A, Roquer J, Serena J, Purroy F, Urra X, Chamorro Á. Clinical improvement within 24 hours from mechanical thrombectomy as a predictor of long-term functional outcome in a multicenter population-based cohort of patients with ischemic stroke. Journal of NeuroInterventional Surgery. 2021;13(2):119-123. DOI:10.1136/neurintsurg-2020-015934. PMID: 32461229. IF: 8,572
Rudilosso S, Rios J, Rodriguez A, Gomis M, Vera V, Gomez M, Renu A, Matos N, Llull L, Purroy F, Amaro S, Terceno M, Obach V, Serena J, Marti J, Cardona P, Molina C, Rodriguez A, Canovas D, Krupinski J, Ustrell X, Torres F, San Roman L, Salvat M, Jimenez FX, Palomeras E, Catena E, Colom C, Cocho D, Baiges J, Aragones JM, Diaz G, Costa X, Almendros MC, et al. Effectiveness of Thrombectomy in Stroke According to Baseline Prognostic Factors: Inverse Probability of Treatment Weighting Analysis of a Population-Based Registry. Journal of Stroke. 2021; 23(3). DOI:10.5853/jos.2021.00962. PMID:34649384. IF: 8,632
Sánchez van Kammen M, Aguiar de Sousa D, Poli S, Cordonnier C, Heldner MR, van de Munckhof A, Krzywicka K, van Haaps T, Ciccone A, Middeldorp S, Levi MM, Kremer Hovinga JA, Silvis S, Hiltunen S, Mansour M, Arauz A, Barboza MA, Field TS, Tsivgoulis G, Nagel S, Lindgren E, Tatlisumak T, Jood K, Putaala J, Ferro JM, Arnold M, et al. [Guisado-Alonso D]. Characteristics and Outcomes of Patients With Cerebral Venous Sinus Thrombosis in SARS-CoV-2 Vaccine-Induced Immune Thrombotic Thrombocytopenia. JAMA Neurology. 2021;78(11):1314-1323. DOI:10.1001/jamaneurol.2021.3619. PMID: 34581763. IF: 29,907
Shoamanesh A, Hart RG, Connolly SJ, Kasner SE, Smith EE, Martí-Fàbregas J, Liu YY, Uchiyama S, Mikulik R, Veltkamp R, O’Donnell MJ, Ntaios G, Muir KW, Field TS, Santo GC, Olavarria V, Mundl H, Lutsep H, Berkowitz SD, Sharma M. Microbleeds and the Effect of Anticoagulation in Patients With Embolic Stroke of Undetermined Source: An Exploratory Analysis of the NAVIGATE ESUS Randomized Clinical Trial. JAMA Neurology. 2021;78(1):11-20. DOI:10.1001/jamaneurol.2020.3836. Erratum in: JAMA Neurology. 2021;78(1):120. PMID: 33074284. IF: 29,907
Terceño M, Silva Y, Bashir S, Vera-Monge VA, Cardona P, Molina C, Chamorro Á, de la Ossa NP, Hernández-Pérez M, Werner M, Camps-Renom P, Rodríguez-Campello A, Cánovas D, Purroy F, Serena J; Catalan Stroke Code and Reperfusion Consortium (Cat-SCR). Impact of general anesthesia on posterior circulation large vessel occlusions after endovascular thrombectomy. International Journal of Stroke. 2021;16(7):792-797. DOI:10.1177/1747493020976247. PMID: 33573525. IF: 6,948
Wang YJ, Pan YS, Li H, Amarenco P, Denison H, Evans SR, Himmelmann A, James S, Birve F, Ladenvall P, Molina CA, Johnston SC, Martí J, Pham DD. Efficacy and Safety of Ticagrelor and Aspirin in Patients With Moderate Ischemic Stroke An Exploratory Analysis of the THALES Randomized Clinical Trial. JAMA Neurology. 2021; 78(9). DOI:10.1001/jamaneurol.2021.2440. PMID:34244703. IF: 29,907

2017 Scientific Report – Cerebrovascular Diseases

Introduction

Main lines of research

Brain neurorepair after stroke.
Role of statins in ischemic and haemorrhagic stroke.
Prevention of cerebral haemorrhage with anticoagulants.
Endothelial progenitor cells in stroke.
Aetiological classification of brain haemorrhage.
Pathophysiology of hematoma growth in acute cerebral haemorrhage.
Benefits and risks of intravenous thrombolysis.
Sonothrombolysis.
Non-invasive monitoring of cerebral flow with applied optic methods.
Participation in clinical trials.

Challenges

Enhance cooperation with other groups in the framework of Spanish stroke research.
Network (RETICS/INVICTUS) and also intrahospital cooperation (the Catalan Institute of Cardiovascular Sciences and the Haemostasis-Thrombosis group) and extra-hospital cooperation (with groups managed by Dr. García-Verdugo in Valencia, Dr. Arús at the Autonomous University of Barcelona, Dr. Anna Planas at Clinic Hospital, Dr. Turgut Durduran at ICFO). To obtain funding from FIS, regional authorities and private companies.
Increase the number of contracted and grant-aided researchers and professionally develop existing researchers.

Team

Group coordination

MARTI FABREGAS, JOAN FGS
jmarti@santpau.cat

Members

Scientific output

Publications 2023

(JIF 2022)

Publications 2022

(JIF 2022)

Camps-Renom P, McCabe J, Martí-Fàbregas J, Giannotti N, Fernandez A, McNulty JP, Baron JC, Barry M, Coutts SB, Cronin S, Delgado R, Dolan E, Foley S, Guasch M, Guisado D, Harbison JA, Horgan G, Kavanagh EC, Marnane M, Martinez A, McDonnell C, Sharma VK, Williams D, Connell MO, Murphy S, Prats L, Kelly PJ. Association of Plaque Inflammation With Stroke Recurrence in Patients With Unproven Benefit From Carotid Revascularization. NEUROLOGY. 2022; 99(2). DOI:10.1212/WNL.0000000000200525. PMID:35418461. IF:9,9 (Q1/1D). Document type: Article.
Carcel J, Muino E, Gallego C, Cullell N, Lledos M, Llucia L, Sobrino T, Campos F, Castillo J, Freijo M, Arenillas JF, Obach V, Alvarez J, Molina CA, Ribo M, Jimenez J, Roquer J, Munoz L, Lopez E, Millan M, Diaz R, Vives C, Serrano G, Segura T, Ibanez L, Heitsch L, Delgado P, Dhar R, Krupinski J, Delgado R, Prats L, Camps-Renom P, Blay N, Sumoy L, de Cid R, Montaner J, Cruchaga C, Lee JM, Martí-Fàbregas J, Fernández-Cadenas I. A Polygenic Risk Score Based on a Cardioembolic Stroke Multitrait Analysis Improves a Clinical Prediction Model for This Stroke Subtype. Frontiers in Cardiovascular Medicine. 2022; 9:940696. DOI:10.3389/fcvm.2022.940696. PMID:35872910. IF:3,6 (Q2/5D). Document type: Article.
Cullell N, Gallego C, Carcel J, Muino E, Llucia L, Lledos M, Martin JM, Molina J, Casas L, Almeria M, Fernández-Cadenas I, Krupinski J. ICA1L Is Associated with Small Vessel Disease: A Proteome-Wide Association Study in Small Vessel Stroke and Intracerebral Haemorrhage. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022; 23(6):3161. DOI:10.3390/ijms23063161. PMID:35328582. IF:5,6 (Q1/3D). Document type: Article.
Cullell N, Soriano C, Gallego C, Carcel J, Torres NP, Muino E, Lledos M, Llucia L, Esteller M, de Moura MC, Montaner J, Fernandez A, Elosua R, Delgado P, Martí-Fàbregas J, Krupinski J, Roquer J, Jimenez J, Fernández-Cadenas I. DNA Methylation and Ischemic Stroke Risk: An Epigenome-Wide Association Study. THROMBOSIS AND HAEMOSTASIS. 2022; 122(10). DOI:10.1055/s-0042-1749328. PMID:35717949. IF:6,7 (Q1/2D). Document type: Article.
Cullell N, Soriano C, Gallego C, Jara M, Muino E, Llucia L, Lledos M, Esteller M, de Moura MC, Montaner J, Rosell A, Delgado P, Martí-Fàbregas J, Krupinski J, Roquer J, Jimenez J, Fernandez I. Altered methylation pattern in EXOC4 is associated with stroke outcome: an epigenome-wide association study. Clinical Epigenetics. 2022; 14(1):124. DOI:10.1186/s13148-022-01340-5. PMID:36180927. IF:5,7 (Q1/2D). Document type: Article.
de la Ossa NP, Abilleira S, Jovin TG, Garcia A, Jimenez X, Urra X, Cardona P, Cocho D, Purroy F, Serena J, Manzanera LS, Vivanco RM, Salvat M, Chamorro A, Gallofre M, Molina CA, Cobo E, Davalos A, Ribo M, Martí J, RACECAT Trial Investigators [Martí-Fàbregas J]. Effect of Direct Transportation to Thrombectomy-Capable Center vs Local Stroke Center on Neurological Outcomes in Patients With Suspected Large-Vessel Occlusion Stroke in Nonurban Areas The RACECAT Randomized Clinical Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 2022; 327(18). DOI:10.1001/jama.2022.4404. PMID:35510397. IF:120,7 (Q1/1D). Document type: Article.
Flores A, Sero L, Gomez M, Ustrell X, Pellise A, Vinas J, Rodriguez P, Monterde A, Castilho G, Rubiera M, Amaro S, Padros M, Cardona P, Martí-Fàbregas J, Molina CA, Serena J, Jimenez FX, Purroy F, Zaragoza J, Cocho D, Palomeras E, Kuprinski J, Mas N, Hernandez M, Sanjurjo E, Carrion D, Costa X, Barcelo M, Monedero J, Catena E, Rybyeba M, Diaz G, de la Ossa NP, Ribo M. The Role of Vascular Imaging atReferral Centers in the Drip and Ship Paradigm. Journal of Stroke & Cerebrovascular Diseases. 2022; 31(1):106209. DOI:10.1016/j.jstrokecerebrovasdis.2021.106209. PMID:34794029. IF:2,5 (Q3/7D). Document type: Article.
Gallego C, Muino E, Carcel J, Llucia L, Lledos M, Martin JM, Cullell N, Fernández-Cadenas I. Genome-Wide Studies in Ischaemic Stroke: Are Genetics Only Useful for Finding Genes?. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022; 23(12):6840. DOI:10.3390/ijms23126840. PMID:35743317. IF:5,6 (Q1/3D). Document type: Review.
Gallego C, Muino E, Cullell N, Carcel J, Lazcano U, Soriano C, Lledos M, Llucia L, Aguilera A, Marin R, Prats L, Camps-Renom P, Delgado R, Martin JM, Delgado P, Martí-Fàbregas J, Montaner J, Krupinski J, Jimenez J, Roquer J, Fernández-Cadenas I. Biological Age Acceleration Is Lower in Women With Ischemic Stroke Compared to Men. STROKE. 2022; 53(7). DOI:10.1161/STROKEAHA.121.037419. PMID:35209739. IF:8,3 (Q1/1D). Document type: Article.
Guisado D, Camps-Renom P, Delgado R, Granell E, Prats L, Martinez A, Guasch M, Acosta MV, Ramos A, Martí-Fàbregas J. Automated scoring of collaterals, blood pressure, and clinical outcome after endovascular treatment in patients with acute ischemic stroke and large-vessel occlusion. Frontiers in Neurology. 2022; 13:944779. DOI:10.3389/fneur.2022.944779. PMID:36016546. IF:3,4 (Q2/5D). Document type: Article.
Ibanez L, Heitsch L, Carrera C, Farias FHG, Del Aguila JL, Dhar R, Budde J, Bergmann K, Bradley J, Harari O, Phuah CL, Lemmens R, Souza A, Moniche F, Cabezas A, Arenillas JF, Krupinksi J, Cullell N, Torres N, Muino E, Carcel J, Martí-Fàbregas J, Delgado R, Marin R, Hornick A, Vives C, Navarro RD, Tur S, Jimenez C, Obach V, Segura T, Serrano G, Chung JW, Roquer J, et al. Multi-ancestry GWAS reveals excitotoxicity associated with outcome after ischaemic stroke. 2022; 145(7). DOI:10.1093/brain/awac080. PMID:35213696. IF:14,5 (Q1/1D). Document type: Article.
Martí-Fàbregas J, Prats-Sánchez L, Ramos-Pachón A. Manejo médico de la hemorragia intracerebral. In: Trillo S, Llull L (Eds.). Manual de neurologia crítica para neurólogos. Ediciones SEN. ISBN: 978-84-124320-5-3. Document type: Book chapter.
Martínez JP, Guerrero R, Medina V, Branera J, Camps-Renom P. Dual-Stentriever technique for retrieval of an unusual middle cerebral artery embolus. 2022; 37(5). DOI:10.1016/j.nrl.2021.08.006. PMID:34509320. IF:3,9 (Q2/4D). Document type: Letter.
Medrano S, Capellades J, Jimenez J, Gonzalez S, Vilas M, Rodriguez A, Ois A, Cuadrado E, Avellaneda C, Fernández-Cadenas I, Merino E, Roquer J, Martí-Fàbregas J, Giralt E. Risk factors analysis according to regional distribution of white matter hyperintensities in a stroke cohort. EUROPEAN RADIOLOGY. 2022; 32(1). DOI:10.1007/s00330-021-08106-2. PMID:34117555. IF:5,9 (Q1/2D). Document type: Article.
Millán M, Ramos A, Dorado L, Bustamante A, Hernández M, Rodríguez L, Gomis M, Remollo S, Castaño C, Werner M, Wenger D, Rubio S, Domínguez M, Terceño M, Paipa AJ, Rodríguez A, Boned S, Camps-Renom P, Cánovas D, Giralt E, López E, Dávalos A, Ros J, Pérez de la Ossa N. Predictors of Functional Outcome After Thrombectomy in Patients With Prestroke Disability in Clinical Practice. 2022; 53(3). DOI:10.1161/STROKEAHA.121.034960. PMID:34702065. IF:8,3 (Q1/1D). Document type: Article.
Mishra A, Malik R, Hachiya T, Jurgenson T, Namba S, Posner DC, Kamanu FK, Koido M, Shi MY, He YY, Georgakis MK, Caro I, Krebs K, Liaw YC, Vaura FC, Lin K, Winsvold BS, Srinivasasainagendra V, Parodi L, Bae HJ, Chauhan G, Chong MCR, Tomppo L, Akinyemi R, Roshchupkin GV, Habib N, Jee YH, Thomassen JQ, Abedi V, Cárcel-Márquez J, Nygaard M, Leonard HL, et al. [Cullell N, Muiño E, Gallego-Fàbrega C, Lledós M, Delgado-Mederos R, Prats-Sánchez L, Camps-Renom P, Martí-Fàbregas J, Fernández-Cadenas I]. Stroke genetics informs drug discovery and risk prediction across ancestries. NATURE. 2022; 611(7934). DOI:10.1038/s41586-022-05165-3. PMID:36180795. IF:64,8 (Q1/1D). Document type: Article.
Pairo E, Rawlik K, Russell CD, Malinauskas T, Wu Y, Millar J, Shen X, Elliott KS, Griffiths F, Oosthuyzen W, Morrice K, Keating S, Wang B, Klaric L, Zechner M, Parkinson N, Siddiq A, Goddard P, Donovan S, Maslove D, Nichol A, Semple MG, Zainy T, Maleady F, Todd L, Salehi S, Knight J, Elgar G, Patch C, Bentley D, Kingsley C, Justice A, Oetjens M, Rader DJ, Fowler TA, et al. [Fernández-Cadenas I, Llucia-Carol M, Cullell N, Muiño E, Cárcel-Márquez J, Martí-Fàbregas J, Jiménez-Xarrié E], GenOMICC C, COVID I, 23andMe I. Whole-genome sequencing reveals host factors underlying critical COVID-19. NATURE. 2022; 607(7917). DOI:10.1038/s41586-022-04576-6. PMID:35255492. IF:64,8 (Q1/1D). Document type: Article.
Pathak GA, Polimanti R, Karjalainen J, Daly M, Ganna A, Daly MJ, Stevens C, Kanai M, Liao RG, Trankiem A, Balaconis MK, Nguyen H, Solomonson M, Veerapen K, Ripatti S, Nkambul L, Bryant S, Sankaran VG, Neale BM, Karczewski KJ, Martin AR, Atkinson EG, Tsuo K, Baya N, Turley P, Gupta R, Walters RK, Palmer DS, Sarma G, Cheng N, Lu W, Churchhouse C, Goldstein JI, King D, et al. [Fernández-Cadenas I, Llucia-Carol M, Cullell N, Muiño E, Cárcel-Márquez J, Martí-Fàbregas J, Jiménez-Xarrié E], COVID-19 Host Genetics Initiative. A first update on mapping the human genetic architecture of COVID-19. NATURE. 2022; 608(7921). DOI:10.1038/s41586-022-04826-7. PMID:35922517. IF:64,8 (Q1/1D). Document type: Editorial material.
Perera KS, Boasquevisque DD, Rao P, Taylor A, Cheng A, Hankey GJ, Lee S, Fabregas JM, Ameriso SF, Field TS, Arauz A, Coutts SB, Arnold M, Mikulik R, Toni D, Mandzia J, Veltkamp RC, Meseguer E, Haeusler KG, Hart RG, Young I. Evaluating Rates of Recurrent Ischemic Stroke Among Young Adults With Embolic Stroke of Undetermined Source The Young ESUS Longitudinal Cohort Study. JAMA Neurology. 2022; 79(5). DOI:10.1001/jamaneurol.2022.0048. PMID:35285869. IF:29 (Q1/1D). Document type: Article.
Prats L, Iruzubieta P, Vesperinas A, Collet R, Martínez A, Guisado D, Camps-Renom P, Delgado R, Guasch M, Ramos A, Rodríguez J, Campo D, Equiza J, de la Riva P, Martínez M, de Arce A, Martí-Fàbregas J. Frequency, Predictors, Etiology, and Outcomes for Deep Intracerebral Hemorrhage without Hypertension. Journal of Stroke & Cerebrovascular Diseases. 2022; 31(3):106293. DOI:10.1016/j.jstrokecerebrovasdis.2021.106293. PMID:35016096. IF:2,5 (Q3/7D). Document type: Article.
Puig N, Camps-Renom P, Camacho M, Aguilera A, Jimenez F, Fernandez A, Marin R, Martí-Fàbregas J, Sanchez JL, Jimenez E, Benitez S. Plasma sICAM-1 as a Biomarker of Carotid Plaque Inflammation in Patients with a Recent Ischemic Stroke. Translational Stroke Research. 2022; 13(5). DOI:10.1007/s12975-022-01002-x. PMID:35237947. IF:6,9 (Q1/1D). Document type: Article.
Renu A, Millan M, San Roman L, Blasco J, Martí-Fàbregas J, Terceno M, Amaro S, Serena J, Urra X, Laredo C, Barranco R, Camps-Renom P, Zarco F, Oleaga L, Cardona P, Castano C, Macho J, Cuadrado E, Vivas E, Lopez A, Guimaraens L, Ramos A, Roquer J, Muchada M, Tomasello A, Davalos A, Torres F, Chamorro A. Effect of Intra-arterial Alteplase vs Placebo Following Successful Thrombectomy on Functional Outcomes in Patients With Large Vessel Occlusion Acute Ischemic Stroke The CHOICE Randomized Clinical Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 2022; 327(9). DOI:10.1001/jama.2022.1645. PMID:35143603. IF:120,7 (Q1/1D). Document type: Article.
Ruiz I, Guisado D, Bulnes V, Green BT. Isolated dilated pupil. BMJ-British Medical Journal. 2022; 376:e069133. DOI:10.1136/bmj-2021-069133. PMID:35361677. IF:105,7 (Q1/1D). Document type: Editorial material.
Sharma M, Smith EE, Pearce LA, Shoamanesh A, Perera KS, Coutts SB, Damgaard D, Ameriso SF, Rha JH, Modrau B, Yoon BW, Romano M, Messe SR, Barlinn J, Lambeck J, Saad F, Berkowitz SD, Mundl H, Connolly SJ, Hart RG, Martí-Fàbregas J, O’Donnell MJ. Frequency and patterns of Brain Infarction in Patients With Embolic Stroke of Undetermined Source: NAVIGATE ESUS Trial. STROKE. 2022; 53(1). DOI:10.1161/STROKEAHA.120.032976. PMID:34538089. IF:8,3 (Q1/1D). Document type: Article.
Sol J, Colas L, Mauri G, Molina J, Galo JD, Torres C, Aymerich N, Ois A, Roquer J, Tur S, Garcia MD, Martí-Fàbregas J, Cruz A, Segura T, Pamplona R, Portero M, Arque G, Jove M, Purroy F. Ischemia preconditioning induces an adaptive response that defines a circulating metabolomic signature in ischemic stroke patients. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2022; 42(12). DOI:10.1177/0271678X221116288. PMID:35869638. IF:6,3 (Q1/2D). Document type: Article.

Publications 2021

Arranz MJ, Gallego C, Martin A, Soler J, Elices M, Dominguez E, Salazar J, Vega D, Briones L, Pascual JC. A genome-wide methylation study reveals X chromosome and childhood trauma methylation alterations associated with borderline personality disorder. Translational Psychiatry. 2021; 11(1):5. DOI:10.1038/s41398-020-01139-z. PMID:33414392. IF:7,989.
Best JG, Ambler G, Wilson D, Lee KJ, Lim JS, Shiozawa M, Koga M, Li LX, Lovelock C, Chabriat H, Hennerici M, Wong YK, Mak HKF, Prats L, Martinez A, Inamura S, Yoshifuji K, Arsava EM, Horstmann S, Purrucker J, Lam BYK, Wong A, Kim YD, Song TJ, Lemmens R, Eppinger S, Gattringer T, Uysal E, Tanriverdi Z, Bornstein NM, Ben E, Hallevi H, et al. [Gomez B, Marti J]. Development of imaging-based risk scores for prediction of intracranial haemorrhage and ischaemic stroke in patients taking antithrombotic therapy after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies. LANCET NEUROLOGY. 2021; 20(4). PMID:33743239. IF:59,935.
Bonaterra A, Fernandez S, Rivas A, Puig N, Benitez S, Pancorbo O, Rodriguez D, Pujadas F, Freijo MD, Tur S, Martinez M, Portela PC, Vera R, Lebrato L, Arenillas JF, Perez S, Montaner J, Sanchez JL, Hernandez M. Comparison of Plasma Lipoprotein Composition and Function in Cerebral Amyloid Angiopathy and Alzheimer’s Disease. Biomedicines. 2021; 9(1):72. DOI:10.3390/biomedicines9010072. PMID:33445800. IF: 4,757
Camps P, Jimenez E, Soler M, Puig N, Aguilera A, Marin R, Prats L, Delgado R, Martinez A, Guisado D, Guasch M, Marti J. Endothelial Progenitor Cells Count after Acute Ischemic Stroke Predicts Functional Outcome in Patients with Carotid Atherosclerosis. Journal of Stroke & Cerebrovascular Diseases. 2021; 30(12): 106144. DOI:10.1016/j.jstrokecerebrovasdis.2021.106144. PMID:34649037. IF: 2,677
Canyelles M, Garcia A, Junza A, Yanes O, Puig N, Ordonez J, Sionis A, Sans J, Alquezar A, Santos D, Rotllan N, Julve J, Tondo M, Escola JC, Blanco F. The Capacity of APOB-Depleted Plasma in Inducing ATP-Binding Cassette A1/G1-Mediated Macrophage Cholesterol Efflux-But Not Gut Microbial-Derived Metabolites-Is Independently Associated with Mortality in Patients with ST-Segment Elevation Myocardial Infarction. Biomedicines. 2021; 9(10):1336. DOI:10.3390/biomedicines9101336. PMID:34680453. IF: 4,757
Carcel J, Cullell N, Muino E, Gallego C, Lledos M, Ibanez L, Krupinski J, Montaner J, Cruchaga C, Lee JM, Gill D, Pare G, Mola M, Roquer J, Jimenez J, Marti J, Fernandez I. Causal Effect of MMP-1 (Matrix Metalloproteinase-1), MMP-8, and MMP-12 Levels on Ischemic Stroke A Mendelian Randomization Study. STROKE. 2021; 52(7). DOI:10.1161/STROKEAHA.120.033041. PMID:33902302. IF: 10,170
Carrera C, Carcel J, Cullell N, Torres N, Muino E, Castillo J, Sobrino T, Campos F, Rodriguez E, Llucia L, Millan M, Munoz L, Lopez E, Bustamante A, Ribo M, Alvarez J, Jimenez J, Roquer J, Giralt E, Soriano C, Mola M, Vives C, Navarro RD, Tur S, Obach V, Arenillas JF, Segura T, Serrano G, Marti J, Delgado R, Freijo MM, Moniche F, et al. [Gallego C, Fernandez I]. Single nucleotide variations in ZBTB46 are associated with post-thrombolytic parenchymal haematoma. BRAIN. 2021; 144. DOI:10.1093/brain/awab090. PMID:33723576. IF: 15,255
Cole JW, Adigun T, Akinyemi R, Akpa OM, Bell S, Chen BW, Conde JJ, Dobao UL, Fernandez I, Fornage M, Gallego C, Jern C, Krawczak M, Lindgren A, Markus HS, Melander O, Owolabi M, Schlicht K, Soderholm M, Srinivasasainagendra V, Tarraga CS, Stenman M, Tiwari H, Corasaniti M, Fecteau N, Guizzardi B, Lopez H, Nguyen K, Gaynor B, O’Connor T, et al. The copy number variation and stroke (CaNVAS) risk and outcome study. PLoS One. 2021; 16(4):e0248791. DOI:10.1371/journal.pone.0248791. PMID:33872305. IF: 3,752
Cullell N, Carcel J, Gallego C, Muino E, Llucia L, Lledos M, Amaut K, Krupinski J, Fernandez I. Sleep/wake cycle alterations as a cause of neurodegenerative diseases: a mendelian randomization study. NEUROBIOLOGY OF AGING. 2021; 106. DOI:10.1016/j.neurobiolaging.2021.05.008. PMID:34130902. IF: 5,133
Genua I, Puig N, Minambres I, Benitez S, Gil P, Grau M, Rivas A, Balague C, Fernandez S, Garcia A, Perez A, Sanchez JL. Changes in the Composition and Function of Lipoproteins after Bariatric Surgery in Patients with Severe Obesity. Journal of Clinical Medicine. 2021; 10(8):1716. DOI:10.3390/jcm10081716. PMID:33923393. IF: 4,964
Gomez A, Lazcano U, Vivanco RM, Prats L, Guisado D, Delgado R, Camps P, Domeno AM, Cuadrado E, Steinhauer EG, Jimenez J, Soriano C, Avellaneda C, Rodriguez A, Marti J, Ois A, Roquer J. Defining Minor Intracerebral Hemorrhage. CEREBROVASCULAR DISEASES. 2021; 50(4). DOI:10.1159/000515169. PMID:33831860. IF: 3,104
Gregori C, Mesquita RC, Favilla CG, Busch DR, Blanco I, Zirak P, Frisk LK, Avtzi S, Maruccia F, Giacalone G, Cotta G, Camps P, Mullen MT, Marti J, Prats L, Martinez A, Kasner SE, Greenberg JH, Zhou C, Edlow BL, Putt ME, Detre JA, Yodh AG, Durduran T, Delgado R. Blood flow response to orthostatic challenge identifies signatures of the failure of static cerebral autoregulation in patients with cerebrovascular disease. BMC Neurology. 2021; 21(1):154. DOI:10.1186/s12883-021-02179-8. PMID:33836684. IF: 2,903
Guasch M, Prats L, Martinez A, Delgado R, Camps P, Guisado D, Abilleira S, Marti J. Patterns of Admission and Outcomes for Patients with Intracranial Hemorrhage in Catalonia, Spain. World Neurosurgery. 2021; 149. DOI:10.1016/j.wneu.2020.12.129. PMID:33412328. IF: 2,210
Guisado-Alonso D, Edo MC, Estrada Alarcón PV, García-Sánchez SM, Font MÀ, Mena Romo L, Marrero-González P, Mengual JJ, Castrillo L, Montull C, Corominas H, Gómez-Choco M. Progression of Large Vessel Disease in Patients With Giant Cell Arteritis-Associated Ischemic Stroke: The Role of Vascular Imaging: A Case Series. JCR-JOURNAL OF CLINICAL RHEUMATOLOGY. 2021;27(8):e418-e424. DOI:10.1097/RHU.0000000000001498. PMID: 32732523. IF: 3,902
Guisado D, Martinez A, Prats L, Delgado R, Camps P, Abilleira S, De la Ossa NP, Ramos A, Cardona P, Rodriguez A, Molina CA, Rudilosso S, Marti J. Reasons for Not Performing Mechanical Thrombectomy A Population-Based Study of Stroke Codes. STROKE. 2021; 52(9). DOI:10.1161/STROKEAHA.120.032648. PMID:34289711. IF: 10,170
Heitsch L, Ibanez L, Carrera C, Binkley MM, Strbian D, Tatlisumak T, Bustamante A, Ribo M, Molina C, Davalos A, Lopez E, Munoz L, Soriano C, Giralt E, Obach V, Slowik A, Pera J, Lapicka K, Derbisz J, Sobrino T, Castillo J, Campos F, Rodriguez E, Arias S, Segura T, Serrano G, Vives C, Diaz R, Tur S, Jimenez C, Marti J, Delgado R, et al. [Cullell N, Muino E, Carcel J, Fernandez I]. Early Neurological Change After Ischemic Stroke Is Associated With 90-Day Outcome. STROKE. 2021; 52(1). DOI:10.1161/STROKEAHA.119.028687. PMID:33317415. IF: 10,170
Kim NY, Hsu J, Talmasov D, Joutsa J, Soussand L, Wu O, Rost NS, Morenas E, Marti J, Pascual A, Corlett PR, Fox MD. Lesions causing hallucinations localize to one common brain network. MOLECULAR PSYCHIATRY. 2021; 26(4). DOI:10.1038/s41380-019-0565-3. PMID:31659272. IF: 13,437
Llucia L, Muino E, Gallego C, Carcel J, Martin J, Lledos M, Cullell N, Fernandez I. Pharmacogenetics studies in stroke patients treated with rtPA: a review of the most interesting findings. PHARMACOGENOMICS. 2021; 22(16). DOI:10.2217/pgs-2021-0100. PMID:34698533. IF: 2,638
Marti J, Guisado D, Delgado R, Martinez A, Prats L, Guasch M, Cardona P, Nunez A, Requena M, Rubiera M, Olive M, Bustamante A, Gomis M, Amaro S, Llull L, Ustrell X, de Oliveira GC, Sero L, Gomez M, Mena L, Serena J, Viturro SB, Purroy F, Vicente M, Rodriguez A, Ois A, Catena E, Garcia MC, Barrachina O, Palomeras E, Krupinski J, et al. [Camps P]. Impact of COVID-19 Infection on the Outcome of Patients With Ischemic Stroke. STROKE. 2021; 52(12). DOI:10.1161/STROKEAHA.121.034883. PMID:34455823. IF: 10,170
Martin L, Camps P, Lleixa C, Pascual E, Diaz J, Rojas R, De Luna N, Gallardo E, Cortes E, Munoz L, Alcolea D, Lleo A, Casasnovas C, Homedes C, Gutierrez G, Jimeno MC, Berciano J, Sedano MJ, Garcia T, Pardo J, Marquez C, Rojas I, Jerico I, Martinez E, de la Tassa GM, Dominguez C, Illa I, Querol L. Serum neurofilament light chain predicts long-term prognosis in Guillain-Barre syndrome patients. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. 2021; 92(1). DOI:10.1136/jnnp-2020-323899. PMID:33154183. IF: 13,654
McCabe JJ, Camps P, Giannotti N, McNulty JP, Coveney S, Murphy S, Barry M, Harbison J, Cronin S, Williams D, Horgan G, Dolan E, Cassidy T, McDonnell C, Kavanagh E, Foley S, Collins S, O’Connell M, Fernandez A, Delgado R, Marnane M, Marti J, Kelly PJ. Carotid Plaque Inflammation Imaged by PET and Prediction of Recurrent Stroke at 5 Years. NEUROLOGY. 2021; 97(23). DOI:10.1212/WNL.0000000000012909. PMID:34610991. IF: 11,800
Millán M, Ramos A, Dorado L, Bustamante A, Hernández M, Rodríguez L, Gomis M, Remollo S, Castaño C, Werner M, Wenger D, Rubio S, Domínguez M, Terceño M, Paipa AJ, Rodríguez A, Boned S, Camps P, Cánovas D, Giralt E, López E, Dávalos A, Ros J, Pérez de la Ossa N. Predictors of Functional Outcome After Thrombectomy in Patients With Prestroke Disability in Clinical Practice. STROKE. 2022; 53(3). DOI:10.1161/STROKEAHA.121.034960. PMID:34702065. IF: 10,170
Muino E, Carcel J, Carrera C, Llucia L, Gallego C, Cullell N, Lledos M, Castillo J, Sobrino T, Campos F, Rodriguez E, Millan M, Munoz L, Bustamante A, Lopez E, Ribo M, Alvarez J, Jimenez J, Roquer J, Giralt E, Soriano C, Vives C, Navarro RD, Tur S, Obach V, Arenillas JF, Segura T, Serrano G, Marti J, Delgado R, Camps P, Prats L, Guisado D, et al., Int Stroke Genetic C, Spanish Stroke Genetic C [Guasch M, Marin R, Martinez A, Fernandez I]. RP11-362K2.2:RP11-767I20.1 Genetic Variation Is Associated with Post-Reperfusion Therapy Parenchymal Hematoma. A GWAS Meta-Analysis. Journal of Clinical Medicine. 2021; 10(14):3137. DOI:10.3390/jcm10143137. PMID:34300314. IF: 4,964
Muino E, Maisterra O, Jimenez J, Cullell N, Carrera C, Torres NP, Carcel J, Gallego C, Lledos M, Gonzalez J, Olmos F, Espejo E, March A, Pujol R, Rodriguez A, Romeral G, Krupinski J, Marti J, Montaner J, Roquer J, Fernandez I. Genome-wide transcriptome study in skin biopsies reveals an association of E2F4 with cadasil and cognitive impairment. Scientific Reports. 2021; 11(1):6846. DOI:10.1038/s41598-021-86349-1. PMID:33767277. IF: 4,996
Nogueira RG, Abdalkader M, Qureshi MM, Frankel MR, Mansour OY, Yamagami H, Qiu Z, Farhoudi M, Siegler JE, Yaghi S, Raz E, Sakai N, Ohara N, Piotin M, Mechtouff L, Eker O, Chalumeau V, Kleinig TJ, Pop R, Liu J, Winters HS, Shang X, Vasquez AR, Blasco J, Arenillas JF, Martinez-Galdamez M, Brehm A, Psychogios MN, Lylyk P, et al. [Ramos-Pachón A]. Global impact of COVID-19 on stroke care. International Journal of Stroke. 2021;16(5):573-584. DOI:10.1177/1747493021991652. PMID: 33459583. IF: 6,948
Pérez C, López A, Gómez C, Aguirre C, de Felipe A, de la Riva P, Calleja S, Arjona A, Serrano M, Navarro MP, Delgado R, Bashir S, Llul L, Egido J, García S, Díez N, Benavente L, de la Torre JD, Tejada H, Vesperinas A, Sánchez L, Trillo S. Management of cerebral venous thrombosis in Spain: MOTIVATE descriptive study. NEUROLOGIA. 2021. DOI:10.1016/j.nrl.2021.05.016. IF: 5,486
Ramos-Araque ME, Siegler JE, Ribo M, Requena M, López C, de Lera M, Arenillas JF, Pérez IH, Gómez-Vicente B, Talavera B, Portela PC, Guillen AN, Urra X, Llull L, Renú A, Nguyen TN, Jillella D, Nahab F, Nogueira R, Haussen D, Then R, Thon JM, Esparragoza LR, Hernández-Pérez M, Bustamante A, Mansour OY, Megahed M, Hassan T, Liebeskind DS, et al.; SVIN Multinational Registry and Task Force [Ramos A]. Stroke etiologies in patients with COVID-19: the SVIN COVID-19 multinational registry. BMC Neurology. 2021;21(1):43. DOI:10.1186/s12883-021-02075-1. PMID: 33514335. IF: 2,903
Ramos-Pachón A, López-Cancio E, Bustamante A, Pérez de la Ossa N, Millán M, Hernández-Pérez M, Garcia-Berrocoso T, Cardona P, Rubiera M, Serena J, Ustrell X, Garcés M, Terceño M, Dávalos A, Montaner J. D-Dimer as Predictor of Large Vessel Occlusion in Acute Ischemic Stroke. Stroke. 2021;52(3):852-858. DOI:10.1161/STROKEAHA.120.031657. PMID: 33563016. IF: 10,170
Ramos A, Garcia A, Millan M, Ribo M, Amaro S, Cardona P, Marti J, Roquer J, Silva Y, Ustrell X, Purroy F, Gomez M, Zaragoza J, Canovas D, Krupinski J, Sala NM, Palomeras E, Cocho D, Redondo L, Repullo C, Sanjurjo E, Carrion D, Lopez M, Almendros MC, Barcelo M, Monedero J, Catena E, Rybyeba M, Diaz G, Jimenez X, Sola S, Hidalgo V, Pueyo MJ, de la Ossa NP, Urra X. Bottlenecks in the Acute Stroke Care System during the COVID-19 Pandemic in Catalonia. CEREBROVASCULAR DISEASES. 2021; 50(5). DOI:10.1159/000516309. PMID:34023822. IF: 3,104
Renú A, Blasco J, Millán M, Martí-Fàbregas J, Cardona P, Oleaga L, Macho J, Molina C, Roquer J, Amaro S, Dávalos A, Zarco F, Laredo C, Tomasello A, Guimaraens L, Barranco R, Castaño C, Vivas E, Ramos A, López-Rueda A, Urra X, Muchada M, Cuadrado-Godía E, Camps-Renom P, Román LS, Ríos J, Leira EC, Jovin T, Torres F, Chamorro Á; CHOICE Investigators. The Chemical Optimization of Cerebral Embolectomy trial: Study protocol. International Journal of Stroke. 2021;16(1):110-116. DOI:10.1177/1747493019895656. PMID: 31852410. IF: 6,948
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Institut de Recerca de l’Hospital de la Santa Creu i Sant Pau