Sant Pau Hospital is a tertiary high complexity university hospital and, together with Fundació Puigvert, covers all specialities in medical care. This complexity leads to a high variety of biomedical translational research to improve patient’s care in multiple fields including inflammatory or immunological processes and on factors linked to the innate immune system, osteoporosis, nephrology, surgery, ageing-related macular degeneration, microbiology and infectious diseases, diabetes, pituitary and other endocrine diseases, respiratory diseases or perinatal health research and clinical approaches based on human cells and tissues. The main focus of this research area is evidence-based translational medicine to improve patients’ care.