Sant Pau - Institut de Recerca

Main lines of research

Off-pump coronary artery by-pass grafting surgery
Mitral repair surgery
Ascending aorta pathology
Pathogenesis of atrial fibrillation after cardiac surgery: electrophisiologic and mitochondrial analysis
Follow-up of sutureless aortic valve prosthesis: Perceval S
Follow-up of surgical check-list implementation
Use of erythropoietin before cardiac surgery
Participation in VISION study (Vascular events In Surgery patients cOhort evaluatioN)-Cardiac Surgery

Challenges

Consolidation as a research group in different cardiac surgery-related fields, specific utureless valve prosthesis
— Perioperative myocardial infarction
Participation in the assessment and validation of new products employed in cardiac surgery: haemostatics, sutures, systems for sternal closure…
Collaboration with different national and international research teams involved in our lines of study

Group coordination

GINEL IGLESIAS, ANTONINO FGS
aginel@santpau.cat

Members

Casellas Casanovas, Sandra FGS
Irabien Ortiz, Angela FGS
Montiel Serrano, Jose FGS
Rosello Diez, Elena FGS
Tauron Ferrer, Manel FGS

Publications 2023

(JIF 2022)

-Ballester C, Alonso J, Cañes L, Vázquez P, Puertas L, Fernández A, Taurón M, Rodríguez A, López N, Rodríguez C, Martínez J. Lysyl oxidase-dependent extracellular matrix crosslinking modulates calcification in atherosclerosis and aortic valve disease. BIOMEDICINE & PHARMACOTHERAPY. 2023; 167:115469. DOI:10.1016/j.biopha.2023.115469. PMID:37729730. IF:6,900 (Q1/1D). Document type: Article.

-Corominas L, Tauron M, Molina M, Tabilo JF, Leta R, Ginel A. Isolated congenital mitral leaflet perforation in a young adult: A case report. Cirugia Cardiovascular. 2023; 30(1). DOI:10.1016/j.circv.2022.06.010. IF:0,300 (Q4/10D). Document type: Article.

-Godoy H, Jimenez V, Tarifa C, Ginel A, Dos JL, Bentzen BH, Hove L, Ciruela F. Increased Density of Endogenous Adenosine A(2A) Receptors in Atrial Fibrillation: From Cellular and Porcine Models to Human Patients. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023; 24(4):3668. DOI:10.3390/ijms24043668. PMID:36835078. IF:4,900 (Q1/3D). Document type: Article.

-Jimenez V, Casabella S, Llach A, Gich I, Casellas S, Ciruela F, Chen SRW, Guerra JM, Ginel A, Benitez R, Cinca J, Tarifa C, Hove L. Beta-blocker treatment of patients with atrial fibrillation attenuates spontaneous calcium release-induced electrical activity. BIOMEDICINE & PHARMACOTHERAPY. 2023; 158:114169. DOI:10.1016/j.biopha.2022.114169. PMID:36592495. IF:6,900 (Q1/1D). Document type: Article.

-Rodríguez A, Tello C, Vergara AC, Fernández C, Moustafa AH, Pinilla CA, Ginel A, Barros AJ, Dilme JF. Case Report: Kommerell's diverticulum and left aberrant subclavian artery stenosis hybrid treatment with branched aortic stent-graft. Frontiers in Cardiovascular Medicine. 2023; 10:1309839. DOI:10.3389/fcvm.2023.1309839. PMID:38155991. IF:2,800 (Q2/4D). Document type: Article.

-Rufa M, Ursulescu A, Baumann P, Ferrer MT. A prospective, international, bicentric study to evaluate PremiCron suture material for cardiac valve surgery – PREMIVALVE a cohort study. Annals Of Medicine And Surgery. 2023; 85(4). DOI:10.1097/MS9.0000000000000442. PMID:37113912. IF:1,700 (Q2/4D). Document type: Article.

-Tarifa C, Jimenez V, Franco R, Montiel J, Guerra J, Ciruela F, Hove L. Expression and Impact of Adenosine A(3) Receptors on Calcium Homeostasis in Human Right Atrium. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023; 24(5):4404. DOI:10.3390/ijms24054404. PMID:36901835. IF:4,900 (Q1/3D). Document type: Article.

-Tarifa C, Vallmitjana A, Jiménez V, Marchena M, Llach A, Herraiz A, Godoy H, Nolla C, Ginel A, Viñolas X, Montiel J, Ciruela F, Echebarria B, Benítez R, Cinca J, Hove L. Spatial Distribution of Calcium Sparks Determines Their Ability to Induce Afterdepolarizations in Human Atrial Myocytes. Jacc-Basic To Translational Science. 2023; 8(1). DOI:10.1016/j.jacbts.2022.07.013. PMID:36777175. IF:8,400 (Q1/1D). Document type: Article.

Publications 2022

(JIF 2022)

Ballester C, Canes L, Alonso J, Puertas L, Tauron M, Rodriguez C, Martinez J. Nuclear receptor NOR-1 (Neuron-derived Orphan Receptor-1) in pathological vascular remodelling and vascular remodelling. Clinica E Investigacion En Arteriosclerosis. 2022; 34(4). DOI:10.1016/j.arteri.2022.03.002. PMID:35581107. Document type: Review.
Blanco R, de la Fuente H, Rodriguez C, Martin L, Sanchez R, Jimenez R, Rodriguez I, Curtabbi A, Garcia MM, Vera A, Rivero F, Cuesta J, Jimenez LJ, Cecconi A, Duran A, Tauron M, Alonso J, Bueno H, Villalba M, Enriquez JA, Robson SC, Alfonso F, Sanchez F, Martinez J, Martin P. CD69 expression on regulatory T cells protects from immune damage after myocardial infarction. JOURNAL OF CLINICAL INVESTIGATION. 2022; 132(21):e152418. DOI:10.1172/JCI152418. PMID:36066993. IF:15,9 (Q1/1D). Document type: Article.
Casabella S, Jimenez V, Tarifa C, Casellas S, Lu TT, Izquierdo P, Gich I, Jimenez M, Ginel A, Guerra JM, Chen SRW, Benitez R, Hove L. Impact of R-Carvedilol on beta 2-Adrenergic Receptor-Mediated Spontaneous Calcium Release in Human Atrial Myocytes. 2022; 10(7):1759. DOI:10.3390/biomedicines10071759. PMID:35885069. IF:4,7 (Q1/3D). Document type: Article.
Castano M, Sbraga F, de la Sota EP, Arribas JM, Camara ML, Voces R, Donado A, Sandoval E, Morales CA, Gonzalez JM, Barquero M, Fletcher D, Rodriguez J, Molina D, Bellido A, Vigil C, Tena MA, Reyes G, Gomez F, Rivas J, Guevara A, Tauron M, Borrego JM, Castillo L, Miralles A, Canovas S, Berastegui E, Aramendi JI, Aldamiz G, Pruna R, Silva J, de Ibarra J, Legarra JJ, Ballester C, Rodriguez R, Daroca T, Paredes F. Extracorporeal membrane oxigenation in COVID-19 patients: Results of the ECMO-COVID Registry of the Spanish Society of Cardiovascular and Endovascular Surgery. Cirugia Cardiovascular. 2022; 29(2). DOI:10.1016/j.circv.2022.01.007. Document type: Article.
Garcia C, Dominguez JN, Lodde V, Munk R, Abdelmohsen K, Gorospe M, Jimenez V, Ginel A, Hove L, Aranega AE, Franco D. Identification of atrial-enriched lncRNA Walras linked to cardiomyocyte cytoarchitecture and atrial fibrillation. FASEB JOURNAL. 2022; 36(1):e22051. DOI:10.1096/fj.202100844RR. PMID:34861058. IF:4,8 (Q1/2D). Document type: Article.
Herraiz A, Tarifa C, Jimenez V, Llach A, Godoy H, Colino H, Nolla C, Casabella S, Izquierdo P, Benitez I, Benitez R, Rosello E, Rodriguez E, Vinolas X, Ciruela F, Cinca J, Hove L. Influence of sex on intracellular calcium homoeostasis in patients with atrial fibrillation. CARDIOVASCULAR RESEARCH. 2022; 118(4). DOI:10.1093/cvr/cvab127. PMID:33788918. IF:10,8 (Q1/1D). Document type: Article.
Jimenez P, Nombela L, Munoz E, del Valle R, Trillo R, Hernandez JMD, Salido L, Elizaga J, Ojeda S, Gila JS, del Blanco BG, Berenguer A, Lasa G, Carrillo CU, Albarran A, Ruiz R, Moreu J, Gheorghe L, Arzamendi D, Yanes G, Diaz J, Perez I, Artaiz M, Vaquerizo B, Cruz I, Ruiz V, Blanco R, Baz JA, Villa M, de Salazar AO, Tascon V, Casellas S, Moreno R. Early clinical outcomes after transaxillary versus transfemoral TAVI. Data from the Spanish TAVI registry. REVISTA ESPANOLA DE CARDIOLOGIA. 2022; 75(6). DOI:10.1016/j.rec.2021.07.019. PMID:34711513. IF:5,9 (Q1/3D). Document type: Article.
Nolla C, Casabella S, Jimenez V, Vallmitjana A, Tarifa C, Herraiz A, Llach A, Tauron M, Montiel J, Cinca J, Chen SRW, Benitez R, Hove L. beta 2-adrenergic stimulation potentiates spontaneous calcium release by increasing signal mass and co-activation of ryanodine receptor clusters. Acta Physiologica. 2022; 234(4):e13736. DOI:10.1111/apha.13736. PMID:34709723. IF:6,3 (Q1/1D). Document type: Article.
Ruiz A, Li C-HP, Valdovinos P, Rodríguez Á, Bonet A, Tauron M, Ligero C, Millan X, Alegret JM, Viladés D, Arzamendi D. Hemolytic Anemia After Surgical Mitral Valve Repair Treated With Transcatheter Edge-to-Edge Device. Jacc: Case Reports. 2022; 4(12). DOI:10.1016/j.jaccas.2022.03.021. Document type: Article.

Publications 2021

Arbelo E, Angera I, Trucco E, Rivas N, Guerra JM, Bisbal F, Jauregui M, Valles E, Martin G, Sbraga F, Tolosana JM, Linhart M, Francisco J, Montiel J, Pereferrer D, Menendez D, Jimenez J, Elamrani A, Borras R, Dallaglio PD, Benito E, Santos A, Rodriguez E, Sarrias A, Gonzalez CE, Marti J, Cabrera S, Mont L. Reduction in new cardiac electronic device implantations in Catalonia during COVID-19. EUROPACE. 2021; 23(3). DOI:10.1093/europace/euab011. PMID:33595062. IF:5,486.
Baghai M, Glauber M, Fontaine R, Castillo JC, Walker AH, Livi U, Montiel J, Royse A, Bisleri G, Pacini D, Argano V, Roumy A, Asimakopoulos G, Solinas M, SURE I. Clinical outcomes after implantation of a sutureless aortic bioprosthesis with concomitant mitral valve surgery: the SURE-AVR registry. Journal of Cardiothoracic Surgery. 2021; 16(1):154. DOI:10.1186/s13019-021-01523-w. PMID:34053453. IF:1,522.
Godoy-Marín H, Duroux R, Jacobson KA, Soler C, Colino-Lage H, Jiménez-Sábado V, Montiel J, Hove-Madsen L, Ciruela F. Adenosine A2A Receptors Are Upregulated in Peripheral Blood Mononuclear Cells from Atrial Fibrillation Patients. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(7):3467. DOI:10.3390/ijms22073467. PMID: 33801676. IF:6,208.
Rosello E, Hove L, Perez V, Munoz C, Artigas V, Padro JM, Dominguez E. Mitochondrial genetic effect on atrial fibrillation: A case-control study. MITOCHONDRION. 2021; 56. DOI:10.1016/j.mito.2020.11.007. PMID:33171269. IF:4,534.

Introduction

Main lines of research

Off-pump coronary artery by-pass grafting surgery
Mitral repair surgery
Ascending aorta pathology
Pathogenesis of atrial fibrillation after cardiac surgery: electrophisiologic and mitochondrial analysis
Follow-up of sutureless aortic valve prosthesis: Perceval S
Follow-up of surgical check-list implementation
Use of erythropoietin before cardiac surgery
Participation in VISION study (Vascular events In Surgery patients cOhort evaluatioN)-Cardiac Surgery

Challenges

Consolidation as a research group in different cardiac surgery-related fields, specific utureless valve prosthesis
— Perioperative myocardial infarction
Participation in the assessment and validation of new products employed in cardiac surgery: haemostatics, sutures, systems for sternal closure…
Collaboration with different national and international research teams involved in our lines of study

Team

Group coordination

GINEL IGLESIAS, ANTONINO FGS
aginel@santpau.cat

Members

Casellas Casanovas, Sandra FGS
Irabien Ortiz, Angela FGS
Montiel Serrano, Jose FGS
Rosello Diez, Elena FGS
Tauron Ferrer, Manel FGS

Scientific output

Publications 2023

(JIF 2022)

Publications 2022

(JIF 2022)

Ballester C, Canes L, Alonso J, Puertas L, Tauron M, Rodriguez C, Martinez J. Nuclear receptor NOR-1 (Neuron-derived Orphan Receptor-1) in pathological vascular remodelling and vascular remodelling. Clinica E Investigacion En Arteriosclerosis. 2022; 34(4). DOI:10.1016/j.arteri.2022.03.002. PMID:35581107. Document type: Review.
Blanco R, de la Fuente H, Rodriguez C, Martin L, Sanchez R, Jimenez R, Rodriguez I, Curtabbi A, Garcia MM, Vera A, Rivero F, Cuesta J, Jimenez LJ, Cecconi A, Duran A, Tauron M, Alonso J, Bueno H, Villalba M, Enriquez JA, Robson SC, Alfonso F, Sanchez F, Martinez J, Martin P. CD69 expression on regulatory T cells protects from immune damage after myocardial infarction. JOURNAL OF CLINICAL INVESTIGATION. 2022; 132(21):e152418. DOI:10.1172/JCI152418. PMID:36066993. IF:15,9 (Q1/1D). Document type: Article.
Casabella S, Jimenez V, Tarifa C, Casellas S, Lu TT, Izquierdo P, Gich I, Jimenez M, Ginel A, Guerra JM, Chen SRW, Benitez R, Hove L. Impact of R-Carvedilol on beta 2-Adrenergic Receptor-Mediated Spontaneous Calcium Release in Human Atrial Myocytes. 2022; 10(7):1759. DOI:10.3390/biomedicines10071759. PMID:35885069. IF:4,7 (Q1/3D). Document type: Article.
Castano M, Sbraga F, de la Sota EP, Arribas JM, Camara ML, Voces R, Donado A, Sandoval E, Morales CA, Gonzalez JM, Barquero M, Fletcher D, Rodriguez J, Molina D, Bellido A, Vigil C, Tena MA, Reyes G, Gomez F, Rivas J, Guevara A, Tauron M, Borrego JM, Castillo L, Miralles A, Canovas S, Berastegui E, Aramendi JI, Aldamiz G, Pruna R, Silva J, de Ibarra J, Legarra JJ, Ballester C, Rodriguez R, Daroca T, Paredes F. Extracorporeal membrane oxigenation in COVID-19 patients: Results of the ECMO-COVID Registry of the Spanish Society of Cardiovascular and Endovascular Surgery. Cirugia Cardiovascular. 2022; 29(2). DOI:10.1016/j.circv.2022.01.007. Document type: Article.
Garcia C, Dominguez JN, Lodde V, Munk R, Abdelmohsen K, Gorospe M, Jimenez V, Ginel A, Hove L, Aranega AE, Franco D. Identification of atrial-enriched lncRNA Walras linked to cardiomyocyte cytoarchitecture and atrial fibrillation. FASEB JOURNAL. 2022; 36(1):e22051. DOI:10.1096/fj.202100844RR. PMID:34861058. IF:4,8 (Q1/2D). Document type: Article.
Herraiz A, Tarifa C, Jimenez V, Llach A, Godoy H, Colino H, Nolla C, Casabella S, Izquierdo P, Benitez I, Benitez R, Rosello E, Rodriguez E, Vinolas X, Ciruela F, Cinca J, Hove L. Influence of sex on intracellular calcium homoeostasis in patients with atrial fibrillation. CARDIOVASCULAR RESEARCH. 2022; 118(4). DOI:10.1093/cvr/cvab127. PMID:33788918. IF:10,8 (Q1/1D). Document type: Article.
Jimenez P, Nombela L, Munoz E, del Valle R, Trillo R, Hernandez JMD, Salido L, Elizaga J, Ojeda S, Gila JS, del Blanco BG, Berenguer A, Lasa G, Carrillo CU, Albarran A, Ruiz R, Moreu J, Gheorghe L, Arzamendi D, Yanes G, Diaz J, Perez I, Artaiz M, Vaquerizo B, Cruz I, Ruiz V, Blanco R, Baz JA, Villa M, de Salazar AO, Tascon V, Casellas S, Moreno R. Early clinical outcomes after transaxillary versus transfemoral TAVI. Data from the Spanish TAVI registry. REVISTA ESPANOLA DE CARDIOLOGIA. 2022; 75(6). DOI:10.1016/j.rec.2021.07.019. PMID:34711513. IF:5,9 (Q1/3D). Document type: Article.
Nolla C, Casabella S, Jimenez V, Vallmitjana A, Tarifa C, Herraiz A, Llach A, Tauron M, Montiel J, Cinca J, Chen SRW, Benitez R, Hove L. beta 2-adrenergic stimulation potentiates spontaneous calcium release by increasing signal mass and co-activation of ryanodine receptor clusters. Acta Physiologica. 2022; 234(4):e13736. DOI:10.1111/apha.13736. PMID:34709723. IF:6,3 (Q1/1D). Document type: Article.
Ruiz A, Li C-HP, Valdovinos P, Rodríguez Á, Bonet A, Tauron M, Ligero C, Millan X, Alegret JM, Viladés D, Arzamendi D. Hemolytic Anemia After Surgical Mitral Valve Repair Treated With Transcatheter Edge-to-Edge Device. Jacc: Case Reports. 2022; 4(12). DOI:10.1016/j.jaccas.2022.03.021. Document type: Article.

Publications 2021

Arbelo E, Angera I, Trucco E, Rivas N, Guerra JM, Bisbal F, Jauregui M, Valles E, Martin G, Sbraga F, Tolosana JM, Linhart M, Francisco J, Montiel J, Pereferrer D, Menendez D, Jimenez J, Elamrani A, Borras R, Dallaglio PD, Benito E, Santos A, Rodriguez E, Sarrias A, Gonzalez CE, Marti J, Cabrera S, Mont L. Reduction in new cardiac electronic device implantations in Catalonia during COVID-19. EUROPACE. 2021; 23(3). DOI:10.1093/europace/euab011. PMID:33595062. IF:5,486.
Baghai M, Glauber M, Fontaine R, Castillo JC, Walker AH, Livi U, Montiel J, Royse A, Bisleri G, Pacini D, Argano V, Roumy A, Asimakopoulos G, Solinas M, SURE I. Clinical outcomes after implantation of a sutureless aortic bioprosthesis with concomitant mitral valve surgery: the SURE-AVR registry. Journal of Cardiothoracic Surgery. 2021; 16(1):154. DOI:10.1186/s13019-021-01523-w. PMID:34053453. IF:1,522.
Godoy-Marín H, Duroux R, Jacobson KA, Soler C, Colino-Lage H, Jiménez-Sábado V, Montiel J, Hove-Madsen L, Ciruela F. Adenosine A2A Receptors Are Upregulated in Peripheral Blood Mononuclear Cells from Atrial Fibrillation Patients. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(7):3467. DOI:10.3390/ijms22073467. PMID: 33801676. IF:6,208.
Rosello E, Hove L, Perez V, Munoz C, Artigas V, Padro JM, Dominguez E. Mitochondrial genetic effect on atrial fibrillation: A case-control study. MITOCHONDRION. 2021; 56. DOI:10.1016/j.mito.2020.11.007. PMID:33171269. IF:4,534.

ASSOCIATED GROUPS

Cardiac Surgery

Main lines of research

Challenges

Group coordination

Members

Publications 2023

Publications 2022

Publications 2021

Main lines of research

Challenges

Group coordination

Members

Publications 2023

Publications 2022

Publications 2021

Institut de Recerca de l’Hospital de la Santa Creu i Sant Pau