A group of Catalan researchers, led by the director of the Digestive Endoscopy Unit of the Digestive Pathology Service of the Hospital de Sant Pau – IIB Sant Pau, Carlos Guarner Argente, have published an article in Gastroenterology which demonstrates that antibiotic prophylaxis is not necessary for ultrasound-guided endoscopic puncture of pancreatic cystic lesions.
You can read the article here
The work consisted of a clinical trial with a group of 226 patients who underwent an evaluation of cystic lesions of their pancreas and required puncture through ultrasound-guided endoscopy. The incidence of infections was shown to be less than 1% and, in addition, did not vary significantly between patients receiving a placebo and the control group, which was given ciprofloxacin prophylaxis. These results may change the established standard procedure in these cases, thus avoiding prophylactic administration of the antibiotic, possible side effects and possible resistances associated with these drugs. The multicenter study involves the Digestive Pathology Service of Sant Pau – IIB Sant Pau, the Autonomous University of Barcelona, the Hospital Clínic – IDIBAPS, the University of Barcelona, the Digestive Pathology Service of the Hospital Universitari Mutua de Terrassa – Terrassa Mutual Research Foundation, the Hospital Joan XXIII of Tarragona, the Hospital de Bellvitge – IDIBELL, and the Center for Networked Biomedical Research on Liver and Digestive Diseases (CIBERehd). This work has been supported by the Carlos III Health Institute, the Spanish Society of Digestive Endoscopy and the Catalan Society of Digestology.
